Elucidating Mechanisms of Pain in Adolescent and Adult Fibrous Dysplasia Patients

Status: Enrolling by invitation
Location: See location...
Intervention Type: Diagnostic Test
Study Type: Interventional
Study Phase: Not Applicable

Pain remains a common and frequently debilitating symptom, particularly during adulthood of Fibrous Dysplasia/McCune-Albright Syndrome (FD/MAS). For many FD/MAS patients, the amount of pain perceived is not commensurate with the level of detectable musculoskeletal pathology. Using a combination of clinical and biological assessments, this investigation aims to understand what drives pain in FD/MAS.

Participation Requirements
Sex: All
Minimum Age: 10
Maximum Age: 45
Healthy Volunteers: Accepts Healthy Volunteers

• Male and Female subjects

• 10-45 years of age

• English Speaking ability sufficient to comprehend consent (with parental assistance if minor)

• Diagnosis of Fibrous Dysplasia

United States
Boston Children's Hospital
Time Frame
Start Date: January 5, 2021
Estimated Completion Date: December 31, 2022
Target number of participants: 40
Other: Fibrous Dysplasia/McCune-Albright Syndrome
20, Fibrous Dysplasia/McCune-Albright Syndrome Patients with or without pain
Other: Healthy Controls
20, matched healthy controls
Related Therapeutic Areas
Collaborators: National Institutes of Health (NIH)
Leads: Boston Children's Hospital

This content was sourced from clinicaltrials.gov

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