MRI-guided Personalized Targeting of the Ventral Intermediate Nucleus (VIM)/Dentato-rubro-thalamic Tract (DRT) for the MRgFUS Tremor Treatment

Status: Completed
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this investigation is to determine the optimal DRT/VIM target location and its safety margins based on MR-SISET imaging features by comparing with postoperative lesions and clinical outcomes in patients with tremor who will undergo the MRgFUS tremor therapy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:

• Male or female

• 18 years of age or older

• Any ethnic background

• History of a primary diagnosis of essential tremor or Parkinson's disease

• Present for the MRgFUS tremor treatment

• Ability to understand and agree to informed consent as determined by referring physician

Locations
United States
New York
NYU Langone
New York
Time Frame
Start Date: September 10, 2020
Completion Date: June 15, 2022
Participants
Target number of participants: 6
Treatments
Experimental: Investigational Scan
The proposed sequence (<15 minutes) will be added as a supplementary sequence only for the preoperative imaging if subjects agree to participate.
Active Comparator: Current Clinical Practice
All patients will undergo a routine clinical preoperative MRI of the brain under general anesthesia to reduce movement artifacts.
Authors
Timothy Shepherd, Sohae Chung
Sponsors
Leads: NYU Langone Health

This content was sourced from clinicaltrials.gov

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