Effect of Vitamin D Supplementation on Autoimmunity and Thyroid Function in Subjects With Hashimoto's Thyroiditis and Vitamin D Deficiency: Clinical Pilot Trial.

Status: Recruiting
Location: See location...
Intervention Type: Dietary Supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this study is to evaluate the effect of vitamin D supplementation on thyroid autoimmunity, thyroid function, and other metabolic and clinical variables associated with the thyroid axis in patients with Hashimoto's thyroiditis and vitamin D deficiency.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: Accepts Healthy Volunteers
View:

• women between 18-45 years old (pre-menopausal stage)

• men between 18-60 years old

• BMI between 18.5-34.9 kg/ m2

• medical diagnosis of Hashimoto's thyroiditis

• treatment with levothyroxine (LT4) with stable dose (from four months from the start of the intervention)

• positive antithyroid antibody (peroxidase and/or thyroglobulin)

• serum 25 (OH) D levels <20 ng / ml.

Locations
Other Locations
Chile
Escuela de Nutrición. Facultad de Farmacia. Universidad de Valparaíso.
Recruiting
Valparaíso
Contact Information
Primary
Isabella A Vicuña, Master
isabella.vicuna@uv.cl
56-976614192
Backup
Claudia A Vega, Master
claudia.vega@uv.cl
5632-2508440
Time Frame
Start Date: November 20, 2020
Estimated Completion Date: December 2021
Participants
Target number of participants: 50
Treatments
Experimental: Vitamin D-correction
Subjects will receive one capsule with 50.000 IU cholecalciferol weekly for 3 months.
Active Comparator: Vitamin D-RDA
Subjects will receive one capsule with 4.200 IU cholecalciferol weekly for 3 months.
Sponsors
Leads: Universidad de Valparaiso

This content was sourced from clinicaltrials.gov

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