Quality of Life and Dynamic Visual Acuity in Patients With Bilateral Vestibulopathy: the Impact of Covert-saccades

Status: Completed
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable

Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia. Visual consequence of vestibular deficit can lead to a severe impairment of their quality of life. However, correcting saccades during rapid head movement, called covert-saccades, have been more recently identified. These saccades, which occur during the head movement in patients with vestibular hypofunction, present a very short latency. They could compensate for the lack of vestibular-ocular reflex and greatly decrease oscillopsia and visual impairment. The objective of this study is to evaluate the potential functional benefice of these compensatory movements in a population of 20 patients with chronic bilateral areflexia, in a cross-sectional study.

Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: No

• Bilateral Vestibular Hypofunction (BVH) with at least two of the tree following criteria

• Mean peak slow phase velocity of 5°/s or less in bilateral bithermal (30 and 44°C) caloric irrigations

• Pathologic Head-impulse test

• VOR gain of <0.25 on rotatory chair tests

• Disorder present for over 6 month

• Comprehension of the experiments instructions

• Patient consent

Other Locations
Unité de Neuro-Ophtalmologie Hôpital Neurologique
Time Frame
Start Date: May 2016
Completion Date: January 2017
Target number of participants: 20
Experimental: Bilateral vestibular hypofunction
Patients suffering from chronic bilateral vestibular hypofunction.
Leads: Hospices Civils de Lyon

This content was sourced from clinicaltrials.gov

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