A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

Who is this study for? Patients with Breast Cancer
What treatments are being studied? Axillary Lymph Node Dissection+Nodal Radiation Therapy
Status: Active, not recruiting
Location: See all (1246) locations...
Intervention Type: Radiation, Procedure
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x rays or protons to kill tumor cells. It is not yet known if radiation therapy works better alone or with lymph node dissection in treating patients with breast cancer previously treated with chemotherapy and surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:

⁃ Pre-Registration Eligibility Criteria:

⁃ Clinical stage T1-3 N1 M0 breast cancer at diagnosis (prior to the start of neoadjuvant chemotherapy) by American Joint Committee on Cancer (AJCC) staging 7th edition

⁃ No inflammatory breast cancer

⁃ No other malignancy within 5 years of registration with the exception of basal cell or squamous cell carcinoma of the skin treated with local resection only or carcinoma in situ of the cervix

⁃ All patients must have had an axillary ultrasound with fine needle aspiration (FNA) or core needle biopsy of axillary lymph nodes documenting axillary metastasis at the time of diagnosis, prior to or at most 14 days after starting neoadjuvant chemotherapy

• Note: Biopsy of intramammary nodes does not fulfill eligibility criteria

⁃ Patients must have had estrogen receptor, progesterone receptor and HER2 status (by immunohistochemistry [IHC] and/or in situ hybridization [ISH]) evaluated on diagnostic core biopsy prior to start of neoadjuvant chemotherapy

• Note: If HER2 status has not been clearly determined (i.e. equivocal/indeterminate), then patients should not be enrolled

⁃ Patients must have completed all planned neoadjuvant chemotherapy prior to surgery; sandwich chemotherapy is not allowed (i.e. anthracycline/cytoxan or taxane chemotherapy planned to be given after surgery); patients must have completed at least 4 cycles of neoadjuvant chemotherapy consisting of an anthracycline and/or taxane-based regimen without evidence of disease progression in the breast or the lymph nodes

• Note: Delays/dose modifications due to toxicities/adverse events are allowed as long as a minimum of 4 cycles of neoadjuvant chemotherapy is administered; more than 4 cycles of neoadjuvant chemotherapy (NAC) may be administered at the discretion of the treating medical oncologist

⁃ Patients with HER-2 positive tumors must have received neoadjuvant trastuzumab, or trastuzumab + pertuzumab, or other approved anti-HER-2 therapy (either with all or with a portion of the neoadjuvant chemotherapy regimen); therapy must be Food and Drug Administration (FDA)-approved targeted anti-HER2 therapy, but additional therapies are allowed as are non-trastuzumab regimens if administered in the context of an Institutional Review Board (IRB)-approved clinical trial

⁃ All patients must have a clinically negative axilla (no bulky adenopathy) on physical examination documented at the completion of neoadjuvant chemotherapy

• Note: an ultrasound of the axilla is not required at completion of neoadjuvant chemotherapy; if performed, its findings do NOT impact eligibility

⁃ No more than 8 weeks of neoadjuvant endocrine therapy prior to the start of neoadjuvant chemotherapy

⁃ No neoadjuvant radiation therapy

⁃ No SLN surgery/excisional biopsy for pathological confirmation of axillary status prior to or during neoadjuvant chemotherapy

⁃ No prior history of ipsilateral breast cancer (invasive disease or ductal carcinoma in situ [DCIS]); lobular carcinoma in situ (LCIS) and benign breast disease is allowed

⁃ No prior ipsilateral axillary surgery, such as excisional biopsy of lymph node(s) or treatment of hidradenitis

⁃ No history of prior or concurrent contralateral invasive breast cancer; benign breast disease; LCIS or DCIS of contralateral breast is allowed

⁃ Patients must not be pregnant or nursing

• Note: Peri-menopausal women must be amenorrheic for > 12 months to be considered not of childbearing potential

⁃ Eastern Cooperative Oncology Group (ECOG) (Zubrod) performance status 0-1

⁃ Intra-Operative Registration/Randomization Criteria:

⁃ Breast surgery (lumpectomy or mastectomy) and sentinel lymph node surgery must be completed within 56 days of the completion of the last dose of neoadjuvant chemotherapy

⁃ A minimum of 1 sentinel node and a maximum of 8 total nodes (sentinel + non-sentinel) are identified and excised; more than 8 nodes identified by either surgeon or pathologist is NOT allowed Note: Patients who do not have an identifiable sentinel lymph node will not proceed to registration/randomization

⁃ At least one lymph node (sentinel or non-sentinel) excised during sentinel lymph node surgery with a metastasis greater than 0.2 mm in greatest dimension identified on intra-operative pathologic assessment

⁃ Note: Isolated tumor cells (metastases less than or equal to 0.2 mm) will be treated as node negative disease (N0i+)

⁃ Note: If on final pathology, more than 8 lymph nodes are seen pathologically, then the patient should discontinue study

⁃ Axillary lymph node dissection (ALND) is not to be performed prior to registration/randomization

⁃ Note: Patients for whom no positive lymph nodes (sentinel or non-sentinel) are found during sentinel lymph node surgery will not proceed to registration/randomization and can be considered for discussion of the NRG NSABP B-51/RTOG 1304 study A Randomized Phase III Clinical Trial Evaluating the Role of Post-mastectomy Chest Wall and Regional Nodal XRT and Post-lumpectomy Regional Nodal XRT in Patients with Documented Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

⁃ Post-Operative Registration/Randomization Criteria:

⁃ For cases where ALND has not been performed and one of the following is true: 1) intra-operative evaluation of sentinel lymph node could not be/was not performed and final pathology identified a positive lymph node (sentinel or non-sentinel) with metastasis greater than 0.2 mm OR 2) lymph node (sentinel or non-sentinel) considered negative on intra-operative evaluation was found to be positive on final pathology (with metastasis greater than 0.2 mm)

⁃ Breast surgery (lumpectomy or mastectomy) and sentinel lymph node surgery must be completed within 56 days of the completion of the last dose of neoadjuvant chemotherapy; negative margin (by either breast conservation or mastectomy) on final pathology where negative margin is defined as no tumor on ink

⁃ At least one lymph node (sentinel or non-sentinel) with a metastasis greater than 0.2 mm in greatest dimension identified on final pathology (for cases where intra-operative evaluation was not performed, or was negative and completion dissection was not performed)

⁃ At least one and no more than 8 lymph nodes (sentinel and non-sentinel) were found by the pathologists to have been actually excised during sentinel lymph node procedure Note: Isolated tumor cells (metastases less than or equal to 0.2 mm) will be treated as node negative disease (N0i+)

⁃ For those patients who also undergo contralateral breast surgery, if invasive disease is found in the contralateral breast, the patient is not eligible for registration /randomization

Locations
United States
Alaska
Alaska Breast Care and Surgery LLC
Anchorage
Alaska Oncology and Hematology LLC
Anchorage
Alaska Regional Hospital
Anchorage
Alaska Women's Cancer Care
Anchorage
Anchorage Associates in Radiation Medicine
Anchorage
Anchorage Oncology Centre
Anchorage
Anchorage Radiation Therapy Center
Anchorage
Katmai Oncology Group
Anchorage
Providence Alaska Medical Center
Anchorage
Fairbanks Memorial Hospital
Fairbanks
Alabama
Southern Cancer Center PC-Daphne
Daphne
Mobile Infirmary Medical Center
Mobile
Southern Cancer Center PC-Mobile
Mobile
Southern Cancer Center PC-Providence
Mobile
Southern Cancer Center PC-Springhill
Mobile
University of South Alabama Mitchell Cancer Institute
Mobile
Arkansas
Mercy Hospital Fort Smith
Fort Smith
CHI Saint Vincent Cancer Center Hot Springs
Hot Springs
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro
University of Arkansas for Medical Sciences
Little Rock
Arizona
Arizona Breast Cancer Specialists-Gilbert
Gilbert
Virginia G Piper Cancer Care-Glendale
Glendale
Arizona Center for Cancer Care-Peoria
Peoria
Arizona Breast Cancer Specialists-Phoenix
Phoenix
Cancer Center at Saint Joseph's
Phoenix
Arizona Breast Cancer Specialists
Scottsdale
Arizona Breast Cancer Specialists-Scottsdale
Scottsdale
Virginia G Piper Cancer Care-Del Camino
Scottsdale
Arizona Center for Cancer Care-Surprise
Surprise
Banner University Medical Center - Tucson
Tucson
University of Arizona Cancer Center-North Campus
Tucson
California
Kaiser Permanente-Deer Valley Medical Center
Antioch
PCR Oncology
Arroyo Grande
Sutter Auburn Faith Hospital
Auburn
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn
AIS Cancer Center at San Joaquin Community Hospital
Bakersfield
Alta Bates Summit Medical Center-Herrick Campus
Berkeley
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank
Mills-Peninsula Medical Center
Burlingame
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park
East Bay Radiation Oncology Center
Castro Valley
Eden Hospital Medical Center
Castro Valley
Community Cancer Institute
Clovis
University Oncology Associates
Clovis
John Muir Medical Center-Concord Campus
Concord
City of Hope Corona
Corona
City of Hope Comprehensive Cancer Center
Duarte
Epic Care-Dublin
Dublin
Kaiser Permanente Dublin
Dublin
Bay Area Breast Surgeons Inc
Emeryville
Epic Care Partners in Cancer Care
Emeryville
Kaiser Permanente-Fremont
Fremont
Fresno Cancer Center
Fresno
Kaiser Permanente-Fresno
Fresno
Saint Jude Medical Center
Fullerton
UC San Diego Moores Cancer Center
La Jolla
Loma Linda University Medical Center
Loma Linda
Cedars Sinai Medical Center
Los Angeles
Kaiser Permanente Los Angeles Medical Center
Los Angeles
Los Angeles County-USC Medical Center
Los Angeles
USC / Norris Comprehensive Cancer Center
Los Angeles
Contra Costa Regional Medical Center
Martinez
Fremont - Rideout Cancer Center
Marysville
Kaiser Permanente-Modesto
Modesto
Memorial Medical Center
Modesto
Community Hospital of Monterey Peninsula
Monterey
El Camino Hospital
Mountain View
Palo Alto Medical Foundation-Camino Division
Mountain View
Sutter Cancer Research Consortium
Novato
Alta Bates Summit Medical Center - Summit Campus
Oakland
Bay Area Tumor Institute
Oakland
Hematology and Oncology Associates-Oakland
Oakland
Highland General Hospital
Oakland
Kaiser Permanente Oakland-Broadway
Oakland
Kaiser Permanente-Oakland
Oakland
Saint Joseph Hospital - Orange
Orange
Desert Regional Medical Center
Palm Springs
Palo Alto Medical Foundation Health Care
Palo Alto
Stanford Cancer Institute Palo Alto
Palo Alto
Huntington Memorial Hospital
Pasadena
Valley Medical Oncology Consultants
Pleasanton
Pomona Valley Hospital Medical Center
Pomona
Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova
Kaiser Permanente- Marshall Medical Offices
Redwood City
Kaiser Permanente-Redwood City
Redwood City
Kaiser Permanente-Richmond
Richmond
Rohnert Park Cancer Center
Rohnert Park
Kaiser Permanente-Roseville
Roseville
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville
Sutter Roseville Medical Center
Roseville
The Permanente Medical Group-Roseville Radiation Oncology
Roseville
Kaiser Permanente - Sacramento
Sacramento
Kaiser Permanente Downtown Commons
Sacramento
Kaiser Permanente-South Sacramento
Sacramento
South Sacramento Cancer Center
Sacramento
Sutter Medical Center Sacramento
Sacramento
University of California Davis Comprehensive Cancer Center
Sacramento
Saint Helena Hospital
Saint Helena
Salinas Valley Memorial
Salinas
Naval Medical Center -San Diego
San Diego
Sharp Memorial Hospital
San Diego
California Pacific Medical Center-Pacific Campus
San Francisco
Kaiser Permanente-San Francisco
San Francisco
Kaiser Permanente-Santa Teresa-San Jose
San Jose
Kaiser Permanente San Leandro
San Leandro
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo
Mills Health Center
San Mateo
Doctors Medical Center- JC Robinson Regional Cancer Center
San Pablo
Kaiser Permanente-San Rafael
San Rafael
Kaiser San Rafael-Gallinas
San Rafael
Kaiser Permanente Medical Center - Santa Clara
Santa Clara
Dominican Santa Cruz Hospital
Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz
Mission Hope Medical Oncology - Santa Maria
Santa Maria
Kaiser Permanente-Santa Rosa
Santa Rosa
Providence Medical Foundation - Santa Rosa
Santa Rosa
City of Hope South Pasadena
South Pasadena
Kaiser Permanente Cancer Treatment Center
South San Francisco
Kaiser Permanente-South San Francisco
South San Francisco
Kaiser Permanente-Stockton
Stockton
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale
Cedars-Sinai Cancer - Tarzana
Tarzana
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee
City of Hope Upland
Upland
Kaiser Permanente Medical Center-Vacaville
Vacaville
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville
Kaiser Permanente-Vallejo
Vallejo
Sutter Solano Medical Center/Cancer Center
Vallejo
Epic Care Cyberknife Center
Walnut Creek
John Muir Medical Center-Walnut Creek
Walnut Creek
Kaiser Permanente-Walnut Creek
Walnut Creek
Presbyterian Intercommunity Hospital
Whittier
Colorado
Rocky Mountain Cancer Centers-Aurora
Aurora
The Medical Center of Aurora
Aurora
University of Colorado Hospital
Aurora
Boulder Community Foothills Hospital
Boulder
Boulder Community Hospital
Boulder
Rocky Mountain Cancer Centers-Boulder
Boulder
Memorial Hospital North
Colorado Springs
Penrose-Saint Francis Healthcare
Colorado Springs
Rocky Mountain Cancer Centers-Penrose
Colorado Springs
Saint Francis Cancer Center
Colorado Springs
UCHealth Memorial Hospital Central
Colorado Springs
Colorado Blood Cancer Institute
Denver
Denver Health Medical Center
Denver
National Jewish Health-Main Campus
Denver
Porter Adventist Hospital
Denver
Presbyterian - Saint Lukes Medical Center - Health One
Denver
Rocky Mountain Cancer Centers-Midtown
Denver
Rocky Mountain Cancer Centers-Rose
Denver
Rose Medical Center
Denver
SCL Health Saint Joseph Hospital
Denver
The Women's Imaging Center
Denver
Mercy Medical Center
Durango
Southwest Oncology PC
Durango
Shaw Cancer Center
Edwards
Mountain Blue Cancer Care Center - Swedish
Englewood
Swedish Medical Center
Englewood
The Melanoma and Skin Cancer Institute
Englewood
Cancer Care and Hematology-Fort Collins
Fort Collins
Poudre Valley Hospital
Fort Collins
Mountain Blue Cancer Care Center
Golden
National Jewish Health-Western Hematology Oncology
Golden
Grand Valley Oncology
Grand Junction
Saint Mary's Hospital and Regional Medical Center
Grand Junction
North Colorado Medical Center
Greeley
UCHealth Greeley Hospital
Greeley
Rocky Mountain Cancer Centers-Greenwood Village
Greenwood Village
Rocky Mountain Cancer Centers-Lakewood
Lakewood
Saint Anthony Hospital
Lakewood
Littleton Adventist Hospital
Littleton
Rocky Mountain Cancer Centers-Littleton
Littleton
Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree
Sky Ridge Medical Center
Lone Tree
Longmont United Hospital
Longmont
Rocky Mountain Cancer Centers-Longmont
Longmont
McKee Medical Center
Loveland
Medical Center of the Rockies
Loveland
Parker Adventist Hospital
Parker
Rocky Mountain Cancer Centers-Parker
Parker
Rocky Mountain Cancer Centers - Pueblo
Pueblo
Saint Mary Corwin Medical Center
Pueblo
National Jewish Health-Northern Hematology Oncology
Thornton
Rocky Mountain Cancer Centers-Thornton
Thornton
SCL Health Lutheran Medical Center
Wheat Ridge
Connecticut
Smilow Cancer Hospital Care Center-Fairfield
Fairfield
Greenwich Hospital
Greenwich
Smilow Cancer Hospital Care Center at Greenwich
Greenwich
Smilow Cancer Hospital Care Center - Guiford
Guilford
Hartford Hospital
Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Hartford
Middlesex Hospital
Middletown
The Hospital of Central Connecticut
New Britain
Smilow Cancer Center/Yale-New Haven Hospital
New Haven
Yale University
New Haven
Yale-New Haven Hospital North Haven Medical Center
North Haven
Norwalk Hospital
Norwalk
Stamford Hospital/Bennett Cancer Center
Stamford
Smilow Cancer Hospital Care Center-Trumbull
Trumbull
Smilow Cancer Hospital Care Center - Waterford
Waterford
Washington, D.c.
MedStar Georgetown University Hospital
Washington
MedStar Washington Hospital Center
Washington
Sibley Memorial Hospital
Washington
Delaware
Beebe South Coastal Health Campus
Frankford
Beebe Medical Center
Lewes
Christiana Care Health System-Christiana Hospital
Newark
Christiana Gynecologic Oncology LLC
Newark
Delaware Clinical and Laboratory Physicians PA
Newark
Helen F Graham Cancer Center
Newark
Medical Oncology Hematology Consultants PA
Newark
Beebe Health Campus
Rehoboth Beach
TidalHealth Nanticoke / Allen Cancer Center
Seaford
Christiana Care Health System-Wilmington Hospital
Wilmington
Florida
AdventHealth Altamonte
Altamonte Springs
John Fitzgerald Kennedy Medical Center
Atlantis
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura
Morton Plant Hospital
Clearwater
Holy Cross Hospital
Fort Lauderdale
University of Florida Health Science Center - Gainesville
Gainesville
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood
Mayo Clinic in Florida
Jacksonville
Jupiter Medical Center
Jupiter
AdventHealth Kissimmee
Kissimmee
Lakeland Regional Health Hollis Cancer Center
Lakeland
Mount Sinai Medical Center
Miami Beach
AdventHealth East Orlando
Orlando
AdventHealth Medical Group Urology at Orlando
Orlando
AdventHealth Orlando
Orlando
Orlando Health Cancer Institute
Orlando
Memorial Hospital West
Pembroke Pines
Martin Medical Center
Stuart
Robert and Carol Weissman Cancer Center at Martin Health
Stuart
Moffitt Cancer Center
Tampa
Moffitt Cancer Center - McKinley Campus
Tampa
Moffitt Cancer Center-International Plaza
Tampa
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa
AdventHealth Winter Park
Winter Park
Georgia
University Cancer and Blood Center LLC
Athens
Emory Saint Joseph's Hospital
Atlanta
Emory University Hospital Midtown
Atlanta
Emory University Hospital/Winship Cancer Institute
Atlanta
Grady Health System
Atlanta
Piedmont Hospital
Atlanta
Augusta University Medical Center
Augusta
John B Amos Cancer Center
Columbus
Dekalb Medical Center
Decatur
Piedmont Fayette Hospital
Fayetteville
Northeast Georgia Medical Center-Gainesville
Gainesville
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah
Low Country Cancer Care
Savannah
Memorial Health University Medical Center
Savannah
Summit Cancer Care-Memorial
Savannah
Hawaii
Hawaii Cancer Care - Savio
'aiea
Pali Momi Medical Center
'aiea
Queen's Cancer Center - Pearlridge
'aiea
The Cancer Center of Hawaii-Pali Momi
'aiea
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu
Hawaii Cancer Care Inc-Liliha
Honolulu
Island Urology
Honolulu
Kaiser Permanente Moanalua Medical Center
Honolulu
Kapiolani Medical Center for Women and Children
Honolulu
Kuakini Medical Center
Honolulu
Queen's Cancer Cenrer - POB I
Honolulu
Queen's Cancer Center - Kuakini
Honolulu
Queen's Medical Center
Honolulu
Straub Clinic and Hospital
Honolulu
The Cancer Center of Hawaii-Liliha
Honolulu
University of Hawaii Cancer Center
Honolulu
Castle Medical Center
Kailua
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue
Iowa
Saint Anthony Regional Hospital
Carroll
Mercy Hospital
Cedar Rapids
Oncology Associates at Mercy Medical Center
Cedar Rapids
Physicians' Clinic of Iowa PC
Cedar Rapids
Medical Oncology and Hematology Associates-West Des Moines
Clive
Mercy Cancer Center-West Lakes
Clive
Greater Regional Medical Center
Creston
Broadlawns Medical Center
Des Moines
Iowa Lutheran Hospital
Des Moines
Iowa Methodist Medical Center
Des Moines
Medical Oncology and Hematology Associates-Des Moines
Des Moines
Medical Oncology and Hematology Associates-Laurel
Des Moines
Mercy Medical Center - Des Moines
Des Moines
University of Iowa/Holden Comprehensive Cancer Center
Iowa City
Mercy Medical Center-Sioux City
Sioux City
Saint Luke's Regional Medical Center
Sioux City
Siouxland Regional Cancer Center
Sioux City
Mercy Medical Center-West Lakes
West Des Moines
Methodist West Hospital
West Des Moines
Idaho
Saint Alphonsus Cancer Care Center-Boise
Boise
Saint Luke's Cancer Institute - Boise
Boise
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell
Kootenai Health - Coeur d'Alene
Coeur D'alene
Walter Knox Memorial Hospital
Emmett
Saint Luke's Cancer Institute - Fruitland
Fruitland
Saint Joseph Regional Medical Center
Lewiston
Idaho Urologic Institute-Meridian
Meridian
Saint Luke's Cancer Institute - Meridian
Meridian
Saint Alphonsus Medical Center-Nampa
Nampa
Saint Luke's Cancer Institute - Nampa
Nampa
Kootenai Clinic Cancer Services - Post Falls
Post Falls
Kootenai Cancer Clinic
Sandpoint
Saint Luke's Cancer Institute - Twin Falls
Twin Falls
Illinois
Rush - Copley Medical Center
Aurora
Illinois CancerCare-Bloomington
Bloomington
Saint Joseph Medical Center
Bloomington
Illinois CancerCare-Canton
Canton
Memorial Hospital of Carbondale
Carbondale
SIH Cancer Institute
Carterville
Illinois CancerCare-Carthage
Carthage
Centralia Oncology Clinic
Centralia
Advocate Illinois Masonic Medical Center
Chicago
John H Stroger Jr Hospital of Cook County
Chicago
Mount Sinai Hospital Medical Center
Chicago
Rush University Medical Center
Chicago
Swedish Covenant Hospital
Chicago
University of Chicago Comprehensive Cancer Center
Chicago
Carle on Vermilion
Danville
Cancer Care Specialists of Illinois - Decatur
Decatur
Decatur Memorial Hospital
Decatur
Northwestern Medicine Cancer Center Kishwaukee
Dekalb
Carle Physician Group-Effingham
Effingham
Crossroads Cancer Center
Effingham
Elmhurst Memorial Hospital
Elmhurst
Illinois CancerCare-Eureka
Eureka
NorthShore University HealthSystem-Evanston Hospital
Evanston
Saint Francis Hospital
Evanston
Illinois CancerCare-Galesburg
Galesburg
Western Illinois Cancer Treatment Center
Galesburg
Northwestern Medicine Cancer Center Delnor
Geneva
NorthShore University HealthSystem-Glenbrook Hospital
Glenview
Ingalls Memorial Hospital
Harvey
Advocate South Suburban Hospital
Hazel Crest
NorthShore University HealthSystem-Highland Park Hospital
Highland Park
Presence Saint Mary's Hospital
Kankakee
Illinois CancerCare-Kewanee Clinic
Kewanee
Condell Memorial Hospital
Libertyville
Illinois CancerCare-Macomb
Macomb
Carle Physician Group-Mattoon/Charleston
Mattoon
Good Samaritan Regional Health Center
Mount Vernon
Edward Hospital/Cancer Center
Naperville
UC Comprehensive Cancer Center at Silver Cross
New Lenox
Cancer Care Center of O'Fallon
O'fallon
Advocate Christ Medical Center
Oak Lawn
University of Chicago Medicine-Orland Park
Orland Park
Illinois CancerCare-Ottawa Clinic
Ottawa
Radiation Oncology of Northern Illinois
Ottawa
Advocate Lutheran General Hospital
Park Ridge
Illinois CancerCare-Pekin
Pekin
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin
Illinois CancerCare-Peoria
Peoria
Methodist Medical Center of Illinois
Peoria
OSF Saint Francis Medical Center
Peoria
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria
Illinois CancerCare-Peru
Peru
Valley Radiation Oncology
Peru
Edward Hospital/Cancer Center?Plainfield
Plainfield
Illinois CancerCare-Princeton
Princeton
SwedishAmerican Regional Cancer Center/ACT
Rockford
Central Illinois Hematology Oncology Center
Springfield
Memorial Medical Center
Springfield
Southern Illinois University School of Medicine
Springfield
Springfield Clinic
Springfield
Southwest Illinois Health Services LLP
Swansea
Carle Cancer Center
Urbana
The Carle Foundation Hospital
Urbana
Northwestern Medicine Cancer Center Warrenville
Warrenville
Illinois CancerCare - Washington
Washington
Rush-Copley Healthcare Center
Yorkville
Indiana
Saint Vincent Anderson Regional Hospital/Cancer Center
Anderson
IU Health West Hospital
Avon
IU Health North Hospital
Carmel
Elkhart Clinic
Elkhart
Elkhart General Hospital
Elkhart
Michiana Hematology Oncology PC-Elkhart
Elkhart
Parkview Hospital Randallia
Fort Wayne
Parkview Regional Medical Center
Fort Wayne
Radiation Oncology Associates PC
Fort Wayne
Goshen Center for Cancer Care
Goshen
Community Cancer Center East
Indianapolis
Community Cancer Center North
Indianapolis
Community Cancer Center South
Indianapolis
Franciscan Health Indianapolis
Indianapolis
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis
IU Health Methodist Hospital
Indianapolis
Saint Vincent Hospital and Health Care Center
Indianapolis
Sidney and Lois Eskenazi Hospital
Indianapolis
Community Howard Regional Health
Kokomo
IU Health La Porte Hospital
La Porte
Franciscan Saint Elizabeth Health - Lafayette East
Lafayette
Franciscan Saint Anthony Health-Michigan City
Michigan City
Woodland Cancer Care Center
Michigan City
Memorial Regional Cancer Center Day Road
Mishawaka
Michiana Hematology Oncology PC-Mishawaka
Mishawaka
Saint Joseph Regional Medical Center-Mishawaka
Mishawaka
Chancellor Center for Oncology
Newburgh
Michiana Hematology Oncology PC-Plymouth
Plymouth
Reid Health
Richmond
Memorial Hospital of South Bend
South Bend
Michiana Hematology Oncology PC-South Bend
South Bend
South Bend Clinic
South Bend
Michiana Hematology Oncology PC-Westville
Westville
Kansas
Cancer Center of Kansas - Chanute
Chanute
Cancer Center of Kansas - Dodge City
Dodge City
Cancer Center of Kansas - El Dorado
El Dorado
Newman Regional Health
Emporia
Cancer Center of Kansas - Fort Scott
Fort Scott
Central Care Cancer Center - Garden City
Garden City
Saint Catherine Hospital
Garden City
Central Care Cancer Center - Great Bend
Great Bend
Saint Rose Ambulatory and Surgery Center
Great Bend
HaysMed University of Kansas Health System
Hays
Cancer Center of Kansas-Independence
Independence
University of Kansas Cancer Center
Kansas City
Cancer Center of Kansas-Kingman
Kingman
Lawrence Memorial Hospital
Lawrence
Kansas Institute of Medicine Cancer and Blood Center
Lenexa
Minimally Invasive Surgery Hospital
Lenexa
Cancer Center of Kansas-Liberal
Liberal
Cancer Center of Kansas-Manhattan
Manhattan
Cancer Center of Kansas - McPherson
Mcpherson
Cancer Center of Kansas - Newton
Newton
Olathe Health Cancer Center
Olathe
Menorah Medical Center
Overland Park
Saint Luke's South Hospital
Overland Park
University of Kansas Cancer Center-Overland Park
Overland Park
University of Kansas Hospital-Indian Creek Campus
Overland Park
Cancer Center of Kansas - Parsons
Parsons
Ascension Via Christi - Pittsburg
Pittsburg
Cancer Center of Kansas - Pratt
Pratt
Cancer Center of Kansas - Salina
Salina
Salina Regional Health Center
Salina
Cotton O'Neil Cancer Center / Stormont Vail Health
Topeka
University of Kansas Health System Saint Francis Campus
Topeka
Cancer Center of Kansas - Wellington
Wellington
University of Kansas Hospital-Westwood Cancer Center
Westwood
Ascension Via Christi Hospitals Wichita
Wichita
Associates In Womens Health
Wichita
Cancer Center of Kansas - Wichita
Wichita
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita
Wesley Medical Center
Wichita
Cancer Center of Kansas - Winfield
Winfield
Kentucky
Oncology Hematology Care Inc-Crestview
Crestview Hills
Saint Elizabeth Medical Center South
Edgewood
Saint Elizabeth Fort Thomas
Fort Thomas
Saint Joseph Hospital East
Lexington
Saint Joseph Radiation Oncology Resource Center
Lexington
University of Kentucky/Markey Cancer Center
Lexington
Jewish Hospital
Louisville
Norton Hospital Pavilion and Medical Campus
Louisville
Norton Suburban Hospital and Medical Campus
Louisville
The James Graham Brown Cancer Center at University of Louisville
Louisville
UofL Health Medical Center Northeast
Louisville
Owensboro Health Mitchell Memorial Cancer Center
Owensboro
Louisiana
Baton Rouge General Medical Center
Baton Rouge
Hematology/Oncology Clinic PLLC
Baton Rouge
Mary Bird Perkins Cancer Center
Baton Rouge
Medical Center of Baton Rouge
Baton Rouge
Ochsner Health Center-Summa
Baton Rouge
Ochsner High Grove
Baton Rouge
Woman's Hospital
Baton Rouge
Ochsner Medical Center Kenner
Kenner
Louisiana State University Health Science Center
New Orleans
Ochsner Baptist Medical Center
New Orleans
Ochsner Medical Center Jefferson
New Orleans
Tulane University Health Sciences Center
New Orleans
University Medical Center New Orleans
New Orleans
LSU Health Sciences Center at Shreveport
Shreveport
Massachusetts
Boston Medical Center
Boston
Brigham and Women's Hospital
Boston
Dana-Farber Cancer Institute
Boston
Lahey Hospital and Medical Center
Burlington
Simonds-Sinon Regional Cancer Center
Fitchburg
Lahey Medical Center-Peabody
Peabody
Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth
Baystate Medical Center
Springfield
UMass Memorial Medical Center - University Campus
Worcester
Maryland
Anne Arundel Medical Center
Annapolis
Greater Baltimore Medical Center
Baltimore
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore
MedStar Good Samaritan Hospital
Baltimore
MedStar Union Memorial Hospital
Baltimore
Saint Agnes Hospital
Baltimore
Sinai Hospital of Baltimore
Baltimore
University of Maryland/Greenebaum Cancer Center
Baltimore
UM Upper Chesapeake Medical Center
Bel Air
Suburban Hospital
Bethesda
Central Maryland Radiation Oncology in Howard County
Columbia
UM Baltimore Washington Medical Center/Tate Cancer Center
Glen Burnie
Northwest Hospital Center
Randallstown
Holy Cross Hospital
Silver Spring
UM Saint Joseph Medical Center
Towson
William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster
Maine
Harold Alfond Center for Cancer Care
Augusta
Eastern Maine Medical Center
Bangor
Lafayette Family Cancer Center-EMMC
Brewer
Central Maine Medical Center
Lewiston
Penobscot Bay Medical Center
Rockport
Michigan
Bixby Medical Center
Adrian
Hickman Cancer Center
Adrian
Saint Joseph Mercy Hospital
Ann Arbor
Bronson Battle Creek
Battle Creek
McLaren Cancer Institute-Bay City
Bay City
IHA Hematology Oncology Consultants-Brighton
Brighton
Saint Joseph Mercy Brighton
Brighton
Henry Ford Cancer Institute-Downriver
Brownstown
IHA Hematology Oncology Consultants-Canton
Canton
Saint Joseph Mercy Canton
Canton
Caro Cancer Center
Caro
IHA Hematology Oncology Consultants-Chelsea
Chelsea
Saint Joseph Mercy Chelsea
Chelsea
Hematology Oncology Consultants-Clarkston
Clarkston
Newland Medical Associates-Clarkston
Clarkston
Henry Ford Macomb Hospital-Clinton Township
Clinton Township
Beaumont Hospital - Dearborn
Dearborn
Ascension Saint John Hospital
Detroit
Henry Ford Hospital
Detroit
Wayne State University/Karmanos Cancer Institute
Detroit
Great Lakes Cancer Management Specialists-Doctors Park
East China Township
Beaumont Hospital - Farmington Hills
Farmington Hills
Weisberg Cancer Treatment Center
Farmington Hills
Genesee Cancer and Blood Disease Treatment Center
Flint
Genesee Hematology Oncology PC
Flint
Genesys Hurley Cancer Institute
Flint
Hurley Medical Center
Flint
McLaren Cancer Institute-Flint
Flint
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids
Mercy Health Saint Mary's
Grand Rapids
Spectrum Health at Butterworth Campus
Grand Rapids
Academic Hematology Oncology Specialists
Grosse Pointe Woods
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods
Michigan Breast Specialists-Grosse Pointe Woods
Grosse Pointe Woods
Allegiance Health
Jackson
Borgess Medical Center
Kalamazoo
Bronson Methodist Hospital
Kalamazoo
West Michigan Cancer Center
Kalamazoo
Sparrow Hospital
Lansing
Hope Cancer Clinic
Livonia
Saint Mary Mercy Hospital
Livonia
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb
Michigan Breast Specialists-Macomb Township
Macomb
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette
Mid-Michigan Medical Center - Midland
Midland
Mercy Memorial Hospital
Monroe
Toledo Clinic Cancer Centers-Monroe
Monroe
McLaren Cancer Institute-Central Michigan
Mount Pleasant
Mercy Health Mercy Campus
Muskegon
Lakeland Hospital Niles
Niles
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores
Ascension Providence Hospitals - Novi
Novi
21st Century Oncology-Pontiac
Pontiac
Hope Cancer Center
Pontiac
Newland Medical Associates-Pontiac
Pontiac
Saint Joseph Mercy Oakland
Pontiac
Lake Huron Medical Center
Port Huron
Spectrum Health Reed City Hospital
Reed City
Great Lakes Cancer Management Specialists-Rochester Hills
Rochester Hills
Michigan Cancer Specialists
Roseville
Cancer Care Associates PC
Royal Oak
Comprehensive Medical Center PLLC
Royal Oak
Hematology Oncology Consultants PC
Royal Oak
Oakland Colon Rectal Associates
Royal Oak
Oakland Medical Group
Royal Oak
William Beaumont Hospital-Royal Oak
Royal Oak
Ascension Saint Mary's Hospital
Saginaw
Oncology Hematology Associates of Saginaw Valley PC
Saginaw
Lakeland Medical Center Saint Joseph
Saint Joseph
Marie Yeager Cancer Center
Saint Joseph
Ascension Providence Hospitals - Southfield
Southfield
Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights
Mitchell Folbe MD PC
Sterling Heights
Premier Hematology Oncology Care
Sterling Heights
Ascension Saint Joseph Hospital
Tawas City
Munson Medical Center
Traverse City
Claudia BR Herke MD PC
Troy
Hematology Oncology Consultants PC-Troy
Troy
Michigan Institute of Urology-Town Center
Troy
William Beaumont Hospital - Troy
Troy
Advanced Breast Care Center PLLC
Warren
Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren
Macomb Hematology Oncology PC
Warren
Michigan Breast Specialists-Warren
Warren
Saint John Macomb-Oakland Hospital
Warren
Henry Ford West Bloomfield Hospital
West Bloomfield
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch
Henry Ford Wyandotte Hospital
Wyandotte
Metro Health Hospital
Wyoming
Huron Gastroenterology PC
Ypsilanti
IHA Hematology Oncology Consultants-Ann Arbor
Ypsilanti
Minnesota
Mayo Clinic Health System in Albert Lea
Albert Lea
Sanford Joe Lueken Cancer Center
Bemidji
Fairview Ridges Hospital
Burnsville
Minnesota Oncology - Burnsville
Burnsville
Mercy Hospital
Coon Rapids
Saint Luke's Hospital of Duluth
Duluth
Fairview Southdale Hospital
Edina
Unity Hospital
Fridley
Hutchinson Area Health Care
Hutchinson
Mayo Clinic Health Systems-Mankato
Mankato
Fairview Clinics and Surgery Center Maple Grove
Maple Grove
Minnesota Oncology Hematology PA-Maplewood
Maplewood
Saint John's Hospital - Healtheast
Maplewood
Abbott-Northwestern Hospital
Minneapolis
Health Partners Inc
Minneapolis
Hennepin County Medical Center
Minneapolis
Monticello Cancer Center
Monticello
New Ulm Medical Center
New Ulm
Mayo Clinic Radiation Therapy-Northfield
Northfield
North Memorial Medical Health Center
Robbinsdale
Mayo Clinic in Rochester
Rochester
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud
Saint Cloud Hospital
Saint Cloud
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park
Regions Hospital
Saint Paul
United Hospital
Saint Paul
Saint Francis Regional Medical Center
Shakopee
Lakeview Hospital
Stillwater
Ridgeview Medical Center
Waconia
Rice Memorial Hospital
Willmar
Minnesota Oncology Hematology PA-Woodbury
Woodbury
Fairview Lakes Medical Center
Wyoming
Missouri
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin
Central Care Cancer Center - Bolivar
Bolivar
Parkland Health Center-Bonne Terre
Bonne Terre
Cox Cancer Center Branson
Branson
Saint Francis Medical Center
Cape Girardeau
Southeast Cancer Center
Cape Girardeau
Saint Luke's Hospital
Chesterfield
University of Missouri - Ellis Fischel
Columbia
Siteman Cancer Center at West County Hospital
Creve Coeur
Parkland Health Center - Farmington
Farmington
Centerpoint Medical Center LLC
Independence
Capital Region Southwest Campus
Jefferson City
Freeman Health System
Joplin
Mercy Hospital Joplin
Joplin
Heartland Hematology and Oncology Associates Incorporated
Kansas City
North Kansas City Hospital
Kansas City
Research Medical Center
Kansas City
Saint Luke's Hospital of Kansas City
Kansas City
The University of Kansas Cancer Center-South
Kansas City
University of Kansas Cancer Center - North
Kansas City
Saint Luke's East - Lee's Summit
Lee's Summit
University of Kansas Cancer Center - Lee's Summit
Lee's Summit
Liberty Radiation Oncology Center
Liberty
University of Kansas Cancer Center at North Kansas City Hospital
North Kansas City
Delbert Day Cancer Institute at PCRMC
Rolla
Mercy Clinic-Rolla-Cancer and Hematology
Rolla
Heartland Regional Medical Center
Saint Joseph
Saint Joseph Oncology Inc
Saint Joseph
Barnes-Jewish Hospital
Saint Louis
Mercy Hospital Saint Louis
Saint Louis
Mercy Hospital South
Saint Louis
Missouri Baptist Medical Center
Saint Louis
Saint Louis Cancer and Breast Institute-South City
Saint Louis
Siteman Cancer Center-South County
Saint Louis
Washington University School of Medicine
Saint Louis
Siteman Cancer Center at Saint Peters Hospital
Saint Peters
Sainte Genevieve County Memorial Hospital
Sainte Genevieve
CoxHealth South Hospital
Springfield
Mercy Hospital Springfield
Springfield
Missouri Baptist Sullivan Hospital
Sullivan
Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills
Mississippi
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus
Baptist Cancer Center-Grenada
Grenada
University of Mississippi Medical Center
Jackson
Baptist Memorial Hospital and Cancer Center-Union County
New Albany
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven
Montana
Community Hospital of Anaconda
Anaconda
Billings Clinic Cancer Center
Billings
Saint Vincent Healthcare
Billings
Bozeman Deaconess Hospital
Bozeman
Saint James Community Hospital and Cancer Treatment Center
Butte
Benefis Healthcare- Sletten Cancer Institute
Great Falls
Great Falls Clinic
Great Falls
Saint Peter's Community Hospital
Helena
Kalispell Regional Medical Center
Kalispell
Community Medical Hospital
Missoula
Saint Patrick Hospital - Community Hospital
Missoula
North Carolina
Randolph Hospital
Asheboro
AdventHealth Infusion Center Asheville
Asheville
Hope Women's Cancer Centers-Asheville
Asheville
Messino Cancer Centers
Asheville
Mission Hospital
Asheville
Cone Health Cancer Center at Alamance Regional
Burlington
Atrium Health Pineville/LCI-Pineville
Charlotte
Atrium Health University City/LCI-University
Charlotte
Carolinas Medical Center/Levine Cancer Institute
Charlotte
Levine Cancer Institute-Ballantyne
Charlotte
Levine Cancer Institute-SouthPark
Charlotte
Novant Health Presbyterian Medical Center
Charlotte
Oncology Specialists of Charlotte
Charlotte
Southern Oncology Specialists-Charlotte
Charlotte
Southeastern Medical Oncology Center-Clinton
Clinton
Atrium Health Cabarrus/LCI-Concord
Concord
Duke University Medical Center
Durham
Southeastern Medical Oncology Center-Goldsboro
Goldsboro
Wayne Memorial Hospital
Goldsboro
Cone Health Cancer Center
Greensboro
Novant Health Breast Surgery - Greensboro
Greensboro
East Carolina University
Greenville
AdventHealth Hendersonville
Hendersonville
Margaret R Pardee Memorial Hospital
Hendersonville
Novant Health Cancer Institute - Huntersville
Huntersville
Southern Oncology Specialists-Huntersville
Huntersville
Onslow Memorial Hospital
Jacksonville
Southeastern Medical Oncology Center-Jacksonville
Jacksonville
Novant Health Cancer Institute - Kernersville
Kernersville
Matthews Radiation Oncology Center
Matthews
Novant Health Cancer Institute - Matthews
Matthews
Cone Heath Cancer Center at Mebane
Mebane
Atrium Health Union/LCI-Union
Monroe
Novant Health Cancer Institute - Mooresville
Mooresville
Novant Health Cancer Institute - Mount Airy
Mount Airy
Annie Penn Memorial Hospital
Reidsville
Atrium Health Cleveland/LCI-Cleveland
Shelby
Iredell Memorial Hospital
Statesville
Novant Health Cancer Institute - Statesville
Statesville
NHRMC Radiation Oncology - Supply
Supply
Novant Health Cancer Institute - Thomasville
Thomasville
Novant Health Cancer Institute - Wilkesboro
Wilkesboro
New Hanover Regional Medical Center/Zimmer Cancer Center
Wilmington
Novant Health Cancer Institute Radiation Oncology - Wilmington
Wilmington
Novant Health Forsyth Medical Center
Winston-salem
Wake Forest University Health Sciences
Winston-salem
North Dakota
Sanford Bismarck Medical Center
Bismarck
Sanford Broadway Medical Center
Fargo
Sanford Clinic North-Fargo
Fargo
Sanford Roger Maris Cancer Center
Fargo
Nebraska
CHI Health Saint Francis
Grand Island
CHI Health Good Samaritan
Kearney
Cancer Partners of Nebraska - Pine Lake
Lincoln
Southeast Nebraska Cancer Center - 68th Street Place
Lincoln
Alegent Health Bergan Mercy Medical Center
Omaha
Alegent Health Immanuel Medical Center
Omaha
Alegent Health Lakeside Hospital
Omaha
Creighton University Medical Center
Omaha
University of Nebraska Medical Center
Omaha
Midlands Community Hospital
Papillion
New Hampshire
Exeter Hospital
Exeter
Dartmouth Hitchcock Medical Center
Lebanon
New Jersey
Memorial Sloan Kettering Basking Ridge
Basking Ridge
Englewood Hospital and Medical Center
Englewood
Hackensack University Medical Center
Hackensack
The Cancer Institute of New Jersey Hamilton
Hamilton
Memorial Sloan Kettering Monmouth
Middletown
Memorial Sloan Kettering Bergen
Montvale
Morristown Medical Center
Morristown
Virtua Memorial
Mount Holly
Jersey Shore Medical Center
Neptune
Rutgers Cancer Institute of New Jersey
New Brunswick
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
New Brunswick
Newark Beth Israel Medical Center
Newark
Saint Joseph's Regional Medical Center
Paterson
Capital Health Medical Center-Hopewell
Pennington
Riverview Medical Center/Booker Cancer Center
Red Bank
Sidney Kimmel Cancer Center Washington Township
Sewell
Robert Wood Johnson University Hospital Somerset
Somerville
Overlook Hospital
Summit
Holy Name Hospital
Teaneck
Virtua Voorhees
Voorhees
New Mexico
Lovelace Women's Hospital
Albuquerque
Presbyterian Kaseman Hospital
Albuquerque
University of New Mexico Cancer Center
Albuquerque
Memorial Medical Center - Las Cruces
Las Cruces
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho
Christus Saint Vincent Regional Cancer Center
Santa Fe
Nevada
Carson Tahoe Regional Medical Center
Carson City
Cancer and Blood Specialists-Henderson
Henderson
Comprehensive Cancer Centers of Nevada - Henderson
Henderson
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson
GenesisCare USA - Henderson
Henderson
Las Vegas Cancer Center-Henderson
Henderson
OptumCare Cancer Care at Seven Hills
Henderson
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas
Ann M Wierman MD LTD
Las Vegas
Cancer and Blood Specialists-Shadow
Las Vegas
Cancer and Blood Specialists-Tenaya
Las Vegas
Cancer Therapy and Integrative Medicine
Las Vegas
Comprehensive Cancer Centers of Nevada
Las Vegas
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas
GenesisCare USA - Fort Apache
Las Vegas
GenesisCare USA - Las Vegas
Las Vegas
GenesisCare USA - Vegas Tenaya
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-San Martin
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Tenaya
Las Vegas
Las Vegas Cancer Center-Medical Center
Las Vegas
OptumCare Cancer Care at Charleston
Las Vegas
OptumCare Cancer Care at Fort Apache
Las Vegas
OptumCare Cancer Care at MountainView
Las Vegas
Radiation Oncology Centers of Nevada Central
Las Vegas
Radiation Oncology Centers of Nevada Southeast
Las Vegas
Summerlin Hospital Medical Center
Las Vegas
University Cancer Center
Las Vegas
University Medical Center of Southern Nevada
Las Vegas
Radiation Oncology Associates
Reno
Renown Regional Medical Center
Reno
Saint Mary's Regional Medical Center
Reno
New York
Montefiore Medical Center - Moses Campus
Bronx
Montefiore Medical Center-Einstein Campus
Bronx
Montefiore Medical Center-Weiler Hospital
Bronx
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn
Roswell Park Cancer Institute
Buffalo
Sands Cancer Center
Canandaigua
Putnam Hospital Center
Carmel
Memorial Sloan Kettering Commack
Commack
Vassar Brothers Fishkill Radiation Oncology Center
Fishkill
The New York Hospital Medical Center of Queens
Flushing
Glens Falls Hospital
Glens Falls
Memorial Sloan Kettering Westchester
Harrison
Ulster Radiation Oncology Center
Kingston
Memorial Sloan Kettering Cancer Center
New York
Mount Sinai Hospital
New York
Mount Sinai Union Square
New York
Mount Sinai West
New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York
NYP/Weill Cornell Medical Center
New York
Vassar Brothers Medical Center
Poughkeepsie
Pluta Cancer Center
Rochester
University of Rochester
Rochester
Memorial Sloan Kettering Sleepy Hollow
Sleepy Hollow
Stony Brook University Medical Center
Stony Brook
State University of New York Upstate Medical University
Syracuse
SUNY Upstate Medical Center-Community Campus
Syracuse
Memorial Sloan Kettering Nassau
Uniondale
Ohio
Cleveland Clinic Akron General
Akron
UHHS-Chagrin Highlands Medical Center
Beachwood
Strecker Cancer Center-Belpre
Belpre
Toledo Clinic Cancer Centers-Bowling Green
Bowling Green
Dayton Physicians LLC-Miami Valley South
Centerville
Miami Valley Hospital South
Centerville
Geauga Hospital
Chardon
Adena Regional Medical Center
Chillicothe
Bethesda North Hospital
Cincinnati
Good Samaritan Hospital - Cincinnati
Cincinnati
Oncology Hematology Care Inc-Anderson
Cincinnati
Oncology Hematology Care Inc-Blue Ash
Cincinnati
Oncology Hematology Care Inc-Eden Park
Cincinnati
Oncology Hematology Care Inc-Kenwood
Cincinnati
Oncology Hematology Care Inc-Mercy West
Cincinnati
The Christ Hospital
Cincinnati
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati
Case Western Reserve University
Cleveland
MetroHealth Medical Center
Cleveland
Columbus Oncology and Hematology Associates Inc
Columbus
Doctors Hospital
Columbus
Grant Medical Center
Columbus
Mount Carmel East Hospital
Columbus
Mount Carmel Health Center West
Columbus
Ohio State University Comprehensive Cancer Center
Columbus
Riverside Methodist Hospital
Columbus
The Mark H Zangmeister Center
Columbus
Dayton Physician LLC-Miami Valley Hospital North
Dayton
Good Samaritan Hospital - Dayton
Dayton
Miami Valley Hospital
Dayton
Miami Valley Hospital North
Dayton
Delaware Health Center-Grady Cancer Center
Delaware
Delaware Radiation Oncology
Delaware
Grady Memorial Hospital
Delaware
Dublin Methodist Hospital
Dublin
Mercy Cancer Center-Elyria
Elyria
Oncology Hematology Care Inc-Healthplex
Fairfield
Armes Family Cancer Center
Findlay
Blanchard Valley Hospital
Findlay
Orion Cancer Care
Findlay
Atrium Medical Center-Middletown Regional Hospital
Franklin
Dayton Physicians LLC-Atrium
Franklin
Dayton Physicians LLC-Wayne
Greenville
Wayne Hospital
Greenville
Mount Carmel Grove City Hospital
Grove City
Greater Dayton Cancer Center
Kettering
Kettering Medical Center
Kettering
Fairfield Medical Center
Lancaster
Lima Memorial Hospital
Lima
Saint Rita's Medical Center
Lima
OhioHealth Mansfield Hospital
Mansfield
Marietta Memorial Hospital
Marietta
OhioHealth Marion General Hospital
Marion
Toledo Clinic Cancer Centers-Maumee
Maumee
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor
UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights
Dayton Physicians LLC-Signal Point
Middletown
Knox Community Hospital
Mount Vernon
Licking Memorial Hospital
Newark
Newark Radiation Oncology
Newark
Saint Charles Hospital
Oregon
Toledo Clinic Cancer Centers-Oregon
Oregon
University Hospitals Parma Medical Center
Parma
Mercy Health Perrysburg Cancer Center
Perrysburg
Southern Ohio Medical Center
Portsmouth
University Hospitals Portage Medical Center
Ravenna
UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky
Dayton Physicians LLC-Wilson
Sidney
Springfield Regional Cancer Center
Springfield
Springfield Regional Medical Center
Springfield
ProMedica Flower Hospital
Sylvania
Mercy Hospital of Tiffin
Tiffin
Mercy Health - Saint Anne Hospital
Toledo
Saint Vincent Mercy Medical Center
Toledo
Toledo Clinic Cancer Centers-Toledo
Toledo
Toledo Community Hospital Oncology Program CCOP
Toledo
University of Toledo
Toledo
Dayton Physicians LLC-Upper Valley
Troy
Upper Valley Medical Center
Troy
Fulton County Health Center
Wauseon
University of Cincinnati Cancer Center-West Chester
West Chester
Saint Ann's Hospital
Westerville
UH Seidman Cancer Center at Saint John Medical Center
Westlake
UHHS-Westlake Medical Center
Westlake
Wright-Patterson Medical Center
Wright-patterson Air Force Base
Genesis Healthcare System Cancer Care Center
Zanesville
Oklahoma
Integris Cancer Institute of Oklahoma
Oklahoma City
Mercy Hospital Oklahoma City
Oklahoma City
University of Oklahoma Health Sciences Center
Oklahoma City
Oregon
Saint Alphonsus Medical Center-Baker City
Baker City
Saint Charles Health System
Bend
Clackamas Radiation Oncology Center
Clackamas
Providence Cancer Institute Clackamas Clinic
Clackamas
Bay Area Hospital
Coos Bay
Providence Milwaukie Hospital
Milwaukie
Providence Newberg Medical Center
Newberg
Saint Alphonsus Medical Center-Ontario
Ontario
Providence Willamette Falls Medical Center
Oregon City
Compass Oncology Rose Quarter
Portland
Oregon Health and Science University
Portland
Providence Portland Medical Center
Portland
Providence Saint Vincent Medical Center
Portland
Salem Hospital
Salem
Pennsylvania
Lehigh Valley Hospital-Cedar Crest
Allentown
UPMC-Heritage Valley Health System Beaver
Beaver
Lehigh Valley Hospital - Muhlenberg
Bethlehem
Crozer-Keystone Regional Cancer Center at Broomall
Broomall
Christiana Care Health System-Concord Health Center
Chadds Ford
Geisinger Medical Center
Danville
Doylestown Hospital
Doylestown
Delaware County Memorial Hospital
Drexel Hill
Pocono Medical Center
East Stroudsburg
Ephrata Cancer Center
Ephrata
Ephrata Community Hospital
Ephrata
Saint Vincent Hospital
Erie
UPMC Hamot
Erie
UPMC Hillman Cancer Center Erie
Erie
Adams Cancer Center
Gettysburg
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg
Cherry Tree Cancer Center
Hanover
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg
Geisinger Medical Center-Cancer Center Hazleton
Hazleton
Penn State Milton S Hershey Medical Center
Hershey
Jefferson Hospital
Jefferson Hills
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown
Armstrong Center for Medicine and Health
Kittanning
Lancaster General Hospital
Lancaster
Sechler Family Cancer Center
Lebanon
Evangelical Community Hospital
Lewisburg
Geisinger Medical Oncology-Lewisburg
Lewisburg
Lewistown Hospital
Lewistown
UPMC Cancer Center at UPMC McKeesport
Mckeesport
Holy Redeemer Hospital and Medical Center
Meadowbrook
Forbes Hospital
Monroeville
UPMC Cancer Center - Monroeville
Monroeville
UPMC-Coraopolis/Heritage Valley Radiation Oncology
Moon
Allegheny Valley Hospital
Natrona Heights
Drexel University School of Medicine
Philadelphia
Thomas Jefferson University Hospital
Philadelphia
Allegheny General Hospital
Pittsburgh
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh
UPMC Jefferson Regional Radiation Oncology
Pittsburgh
UPMC-Magee Womens Hospital
Pittsburgh
UPMC-Passavant Hospital
Pittsburgh
UPMC-Presbyterian Hospital
Pittsburgh
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh
UPMC-Saint Margaret
Pittsburgh
UPMC-Shadyside Hospital
Pittsburgh
West Penn Hospital
Pittsburgh
Guthrie Medical Group PC-Robert Packer Hospital
Sayre
UPMC Cancer Center at UPMC Northwest
Seneca
UPMC Uniontown Hospital Radiation Oncology
Uniontown
UPMC Washington Hospital Radiation Oncology
Washington
Wexford Health and Wellness Pavilion
Wexford
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-barre
Asplundh Cancer Pavilion
Willow Grove
UPMC Memorial
York
WellSpan Health-York Cancer Center
York
WellSpan Health-York Hospital
York
Rhode Island
Miriam Hospital
Providence
Radiation Oncology Associates Incorporated
Providence
Rhode Island Hospital
Providence
Women and Infants Hospital
Providence
Kent Hospital
Warwick
South Carolina
AnMed Health Cancer Center
Anderson
Prisma Health Cancer Institute - Spartanburg
Boiling Springs
Bon Secours Saint Francis Hospital
Charleston
Charleston Oncology - Roper
Charleston
Charleston Oncology - Saint Francis
Charleston
Lowcountry Hematology Oncology PA-North Charleston
Charleston
Lowcountry Hematology Oncology PA-West Ashley
Charleston
Medical University of South Carolina
Charleston
Roper Hospital
Charleston
Prisma Health Cancer Institute - Easley
Easley
Tidelands Georgetown Memorial Hospital
Georgetown
Greenville Health System Cancer Institute-Andrews
Greenville
Prisma Health Cancer Institute - Butternut
Greenville
Prisma Health Cancer Institute - Eastside
Greenville
Prisma Health Cancer Institute - Faris
Greenville
Prisma Health Greenville Memorial Hospital
Greenville
Saint Francis Cancer Center
Greenville
Saint Francis Hospital
Greenville
Self Regional Healthcare
Greenwood
Gibbs Cancer Center-Pelham
Greer
Prisma Health Cancer Institute - Greer
Greer
Carolina Blood and Cancer Care Associates PA-Lancaster
Lancaster
Lancaster Radiation Therapy Center
Lancaster
Lowcountry Hematology Oncology PA-Mount Pleasant
Mount Pleasant
Carolina Blood and Cancer Care Associates PA
Rock Hill
Levine Cancer Institute-Rock Hill
Rock Hill
Rock Hill Radiation Therapy Center
Rock Hill
Prisma Health Cancer Institute - Seneca
Seneca
Spartanburg Medical Center
Spartanburg
South Dakota
Sanford Cancer Center Oncology Clinic
Sioux Falls
Sanford USD Medical Center - Sioux Falls
Sioux Falls
Tennessee
Erlanger Medical Center
Chattanooga
Memorial Hospital
Chattanooga
The West Clinic - Wolf River
Germantown
Jackson-Madison County General Hospital
Jackson
University of Tennessee - Knoxville
Knoxville
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis
Baptist Memorial Hospital for Women
Memphis
Methodist Hospital
Memphis
The West Clinic - Mid-Town
Memphis
University of Tennessee Health Science Center
Memphis
Meharry Medical College
Nashville
Nashville Breast Center
Nashville
Vanderbilt Breast Center at One Hundred Oaks
Nashville
Vanderbilt University/Ingram Cancer Center
Nashville
Texas
The Don and Sybil Harrington Cancer Center
Amarillo
Texas Oncology-Arlington South
Arlington
Texas Oncology PA Beaumont
Beaumont
Texas Oncology Bedford
Bedford
Saint Joseph Regional Cancer Center
Bryan
MD Anderson in The Woodlands
Conroe
Baylor University Medical Center
Dallas
Parkland Memorial Hospital
Dallas
UT Southwestern/Simmons Cancer Center-Dallas
Dallas
Texas Oncology - Denison Cancer Center
Denison
Texas Oncology-Flower Mound
Flower Mound
University of Texas Medical Branch
Galveston
Texas Oncology-Grapevine
Grapevine
M D Anderson Cancer Center
Houston
MD Anderson West Houston
Houston
Baylor Medical Center at Irving
Irving
Doctor's Hospital of Laredo
Laredo
MD Anderson League City
League City
UTMB Cancer Center at Victory Lakes
League City
Texas Tech University Health Sciences Center-Lubbock
Lubbock
UMC Cancer Center / UMC Health System
Lubbock
Texas Oncology-McKinney
Mckinney
West Texas Cancer Center
Odessa
Texas Oncology-Plano West
Plano
Scott and White Healthcare Round Rock
Round Rock
MD Anderson in Sugar Land
Sugar Land
Texas Oncology Cancer Center Sugar Land
Sugar Land
Scott and White Memorial Hospital
Temple
Utah
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork
Sandra L Maxwell Cancer Center
Cedar City
Farmington Health Center
Farmington
Logan Regional Hospital
Logan
Intermountain Medical Center
Murray
McKay-Dee Hospital Center
Ogden
Utah Valley Regional Medical Center
Provo
Riverton Hospital
Riverton
Dixie Medical Center Regional Cancer Center
Saint George
Huntsman Cancer Institute/University of Utah
Salt Lake City
LDS Hospital
Salt Lake City
University of Utah Sugarhouse Health Center
Salt Lake City
Utah Cancer Specialists-Salt Lake City
Salt Lake City
South Jordan Health Center
South Jordan
Virginia
Inova Alexandria Hospital
Alexandria
Sentara Martha Jefferson Hospital
Charlottesville
University of Virginia Cancer Center
Charlottesville
Inova Fair Oaks Hospital
Fairfax
Inova Fairfax Hospital
Falls Church
Fredericksburg Oncology Inc
Fredericksburg
Hematology Oncology Associates of Fredericksburg Inc
Fredericksburg
Mary Washington Hospital
Fredericksburg
Sentara Cancer Institute at Sentara CarePlex Hospital
Hampton
Bon Secours Memorial Regional Medical Center
Mechanicsville
Bon Secours Saint Francis Medical Center
Midlothian
Sentara Leigh Hospital
Norfolk
Sentara Norfolk General Hospital
Norfolk
Naval Medical Center - Portsmouth
Portsmouth
Bon Secours Cancer Institute at Reynolds Crossing
Richmond
Bon Secours Saint Mary's Hospital
Richmond
VCU Massey Cancer Center at Stony Point
Richmond
Virginia Commonwealth University/Massey Cancer Center
Richmond
Sentara Princess Anne Hospital
Virginia Beach
Sentara Virginia Beach General Hospital
Virginia Beach
Vermont
Central Vermont Medical Center/National Life Cancer Treatment
Berlin
University of Vermont and State Agricultural College
Burlington
University of Vermont Medical Center
Burlington
Rutland Regional Medical Center
Rutland
Norris Cotton Cancer Center-North
Saint Johnsbury
Washington
Providence Regional Cancer System-Aberdeen
Aberdeen
Cancer Care Center at Island Hospital
Anacortes
MultiCare Auburn Medical Center
Auburn
Virginia Mason Bainbridge Island Medical Center
Bainbridge Island
Overlake Medical Center
Bellevue
Swedish Cancer Institute-Eastside Oncology Hematology
Bellevue
PeaceHealth Saint Joseph Medical Center
Bellingham
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton
Harrison Medical Center
Bremerton
Highline Medical Center-Main Campus
Burien
Providence Regional Cancer System-Centralia
Centralia
Swedish Cancer Institute-Edmonds
Edmonds
Providence Regional Cancer Partnership
Everett
Virginia Mason Federal Way Medical Center
Federal Way
MultiCare Gig Harbor Medical Park
Gig Harbor
Tacoma/Valley Radiation Oncology Centers-Gig Harbor
Gig Harbor
Swedish Cancer Institute-Issaquah
Issaquah
Kadlec Clinic Hematology and Oncology
Kennewick
Northwest Cancer Clinic
Kennewick
Tri-Cities Cancer Center
Kennewick
Providence Regional Cancer System-Lacey
Lacey
PeaceHealth Saint John Medical Center
Longview
Virginia Mason Lynnwood Medical Center
Lynnwood
Jefferson Healthcare
Port Townsend
Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo
Peninsula Cancer Center
Poulsbo
MultiCare Good Samaritan Hospital
Puyallup
Tacoma/Valley Radiation Oncology Centers-Puyallup
Puyallup
Valley Medical Center
Renton
Fred Hutchinson Cancer Research Center
Seattle
Kaiser Permanente Washington
Seattle
Minor and James Medical PLLC
Seattle
Pacific Gynecology Specialists
Seattle
Seattle Cancer Care Alliance
Seattle
Seattle Cancer Care Alliance at Northwest Hospital
Seattle
Swedish Medical Center-Ballard Campus
Seattle
Swedish Medical Center-Cherry Hill
Seattle
Swedish Medical Center-First Hill
Seattle
University of Washington Medical Center - Montlake
Seattle
Virginia Mason Medical Center
Seattle
PeaceHealth United General Medical Center
Sedro-woolley
Providence Regional Cancer System-Shelton
Shelton
Evergreen Hematology and Oncology PS
Spokane
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
Spokane
MultiCare Deaconess Cancer and Blood Specialty Center - North
Spokane
MultiCare Deaconess Cancer and Blood Specialty Center - Valley
Spokane Valley
MultiCare Tacoma General Hospital
Tacoma
Northwest Medical Specialties PLLC
Tacoma
Saint Joseph Medical Center
Tacoma
Tacoma/Valley Radiation Oncology Centers-Jackson Hall
Tacoma
Tacoma/Valley Radiation Oncology Centers-Saint Joe's
Tacoma
Compass Oncology Vancouver
Vancouver
PeaceHealth Southwest Medical Center
Vancouver
Providence Saint Mary Regional Cancer Center
Walla Walla
Wenatchee Valley Hospital and Clinics
Wenatchee
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima
Providence Regional Cancer System-Yelm
Yelm
Wisconsin
Ascension Saint Elizabeth Hospital
Appleton
Fox Valley Surgical Associates Limited
Appleton
ThedaCare Regional Cancer Center
Appleton
ThedaCare Regional Medical Center - Appleton
Appleton
Ascension Southeast Wisconsin Hospital - Elmbrook Campus
Brookfield
Aurora Cancer Care-Southern Lakes VLCC
Burlington
Ascension Calumet Hospital
Chilton
HSHS Sacred Heart Hospital
Eau Claire
Marshfield Medical Center-EC Cancer Center
Eau Claire
Aurora Health Center-Fond du Lac
Fond Du Lac
Ascension Saint Francis - Reiman Cancer Center
Franklin
Ascension Southeast Wisconsin Hospital - Franklin
Franklin
Aurora Health Care Germantown Health Center
Germantown
Aurora Cancer Care-Grafton
Grafton
Aurora BayCare Medical Center
Green Bay
Bellin Memorial Hospital
Green Bay
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay
Saint Vincent Hospital Cancer Center Green Bay
Green Bay
UW Cancer Center Johnson Creek
Johnson Creek
Aurora Cancer Care-Kenosha South
Kenosha
Gundersen Lutheran Medical Center
La Crosse
University of Wisconsin Carbone Cancer Center
Madison
Aurora Bay Area Medical Group-Marinette
Marinette
Bay Area Medical Center
Marinette
Marshfield Medical Center
Marshfield
Marshfield Medical Center-Marshfield
Marshfield
Froedtert Menomonee Falls Hospital
Menomonee Falls
Ascension Southeast Wisconsin Hospital - Saint Joseph Campus
Milwaukee
Aurora Cancer Care-Milwaukee
Milwaukee
Aurora Saint Luke's Medical Center
Milwaukee
Aurora Sinai Medical Center
Milwaukee
Medical College of Wisconsin
Milwaukee
Marshfield Clinic-Minocqua Center
Minocqua
Surgical Associates of Neenah SC
Neenah
Cancer Center of Western Wisconsin
New Richmond
Drexel Town Square Health Center
Oak Creek
Ascension Mercy Hospital
Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh
Ascension All Saints Hospital
Racine
Aurora Cancer Care-Racine
Racine
Ascension Saint Mary's Hospital
Rhinelander
Marshfield Medical Center-Rice Lake
Rice Lake
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan
Ascension Saint Michael's Hospital
Stevens Point
Marshfield Clinic Stevens Point Center
Stevens Point
Aurora Medical Center in Summit
Summit
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers
Aurora Cancer Care-Waukesha
Waukesha
Marshfield Clinic-Wausau Center
Wausau
Aurora Cancer Care-Milwaukee West
Wauwatosa
Aurora West Allis Medical Center
West Allis
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend
Diagnostic and Treatment Center
Weston
Marshfield Medical Center - Weston
Weston
West Virginia
United Hospital Center
Bridgeport
Edwards Comprehensive Cancer Center
Huntington
Saint Mary's Medical Center
Huntington
West Virginia University Healthcare
Morgantown
Camden Clark Medical Center
Parkersburg
Wyoming
Cheyenne Regional Medical Center-West
Cheyenne
Big Horn Basin Cancer Center
Cody
Billings Clinic-Cody
Cody
Welch Cancer Center
Sheridan
Other Locations
Canada
Royal Victoria Regional Health Centre
Barrie
Cross Cancer Institute
Edmonton
London Regional Cancer Program
London
CIUSSSEMTL-Hopital Maisonneuve-Rosemont
Montreal
Jewish General Hospital
Montreal
The Research Institute of the McGill University Health Centre (MUHC)
Montreal
Ottawa Hospital and Cancer Center-General Campus
Ottawa
CHU de Quebec-Hopital du Saint-Sacrement (HSS)
Quebec City
Allan Blair Cancer Centre
Regina
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John
North York General Hospital
Toronto
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto
University Health Network-Princess Margaret Hospital
Toronto
CancerCare Manitoba
Winnipeg
Puerto Rico
Cancer Center-Metro Medical Center Bayamon
Bayamon
Doctors Cancer Center
Manati
San Juan City Hospital
San Juan
San Juan Community Oncology Group
San Juan
Time Frame
Start Date: February 7, 2014
Estimated Completion Date: January 1, 2024
Participants
Target number of participants: 2012
Treatments
Other: Arm 1: ALND + nodal radiation therapy
Surgery: For patients randomized to axillary lymph node dissection (ALND), it is recommended that a complete level I and II dissection with resection of minimum of a total of 8 lymph nodes (SLN and ALND together) be done. Level III dissection is not required, but may be performed at the discretion of the surgeon. If fewer than 8 lymph nodes (SLN and ALND together) are resected, then the patient will discontinue protocol treatment.~Radiation Therapy: Radiation is delivered to the breast/chest wall, undissected axilla, supraclavicular nodes and internal mammary nodes in the first 3 intercostal spaces. Treatment will be given 5 days a week over 5-6 weeks.
Other: Arm 2: Axillary radiation and nodal radiation therapy
Radiation Therapy: Radiation is delivered to the breast/chest wall, full axilla including Levels I, II, III, supraclavicular nodes and internal mammary nodes in the first 3 intercostal spaces. Treatment will be given 5 days a week over 5-6 weeks.
Authors
Steven J. Feigenberg, Deborah W. Wilbur, Richard E. Fine, Shawna C. Willey, Constance Stoehr, Ethan S. Rogers, William R. Robinson, Aimee D. Kohn, Nicolas Ajkay, Jennifer Slim, Thomas B. Julian, Priscilla F. McAuliffe, Jessica A. Wernberg, Benjamin J. George, Georges F. Hatoum, Gary V. Burton, Sarah L. Blair, Preeti D. Subhedar, Kristine L. Widders, Vivian J. Bea, Amy E. Cyr, Kathryn M. Leininger, Thomas J. Gergel, Lynn T. Dengel, Barbara S. Craft, Kenneth L. Smith, Adam W. Nowlan, Stephanie G. Fine, David M. Dubin, Christy M. Kesslering, Ana Maria Lopez, Robert J. Behrens, Nancy DeMore, Gregory J. Zanieski, Mahvish Muzaffar, Vasudha Lingareddy, Kelly K. Hunt, William E. Lawler, Brett W. Cox, Thomas H. Openshaw, Harvey B. Wilds, Adam C. Berger, Ashley A. Hendrix, Jessica M. Bensenhaver, Judy A. Tjoe, Timothy J. Pluard, Joni A. Tilford, Dawn J. Leonard, Philip J. Stella, Connie D. Uzel, Bachir J. Sakr, Roger S. Wilson, Bryan A. Faller, Roberto Diaz, Alan P. Mullins, Nora T. Jaskowiak, Muhammad A. Salamat, Nicole Kounalakis, Sonali Rudra, Alicia M. Terando, Eleanor E. Harris, William M. Sikov, Thomas J. Reid, Janet K. Ihde, Lori F. Gentile, Kendra M. Harris, Sharon S. Lum, Madhavi K. Toke, Shirnett K. Williamson, Louis Fehrenbacher, Bruce J. Averbook, Rebecca L. Aft, Anna B. Katz, Dona C. Hobart, Arpana M. Naik, Edward J. Clifford, Jay W. Carlson, Michael Maroules, Barbara A. Ward, Marissa M. Howard-McNatt, Jeffrey L. Berenberg, Brian J. O'Hea, Peter W. Blumencranz, Costanza Cocilovo, Elizabeth A. Shaughnessy, Mehmet S. Copur, William J. Irvin, Robert R. Shenk, Doreen M. Agnese, Michael J. Schultz, Ralph L. Corsetti, Mona Karim, Michael A. Schwartz, Jennifer B. Manders, Yadyra Rivera, Naveed A. Rana, Howard A. Zaren, James E. Radford, Samer S. Kasbari, Donald J. Jurgens, Gretchen M. Ahrendt, Sarah J. Sinclair, Jessica F. Partin, Linda K. Han, Jeffrey K. Giguere, Parul N. Barry, Thomas E. Lad, Mehra Golshan, Addison R. Tolentino, Robin T. Zon, Timothy D. Moore, Jeffrey P. Lamont, Paul M. Barr, Susan K. Boolbol, Robert B. Donegan, Judy C. Boughey, John M. Schallenkamp, Ellis G. Levine, Angela J. Keleher, Amanda L. Kong, James N. Atkins, Richard J. Bold, Lisa Bailey, Harry D. Bear, Lora L. Hebert, Gregory A. Masters, Nibal Saad, Matthew M. Poppe, Keren Sturtz, Mary E. Young, Arvinder S. Bir, Bethany M. Anderson, Diana C. Medgyesy, Anna M. Leung, Brian K. Chang, Brian J. Heller, Joseph M. Guenther, Douglas A. Miller, Lindi H. VanderWalde, Maureen T. Kavanah, Kellie S. Condra, John Hausdorff, Steven A. Akman, David J. Tate, Patricia H. Hardenbergh, Thomas Kim, Carlos A. Alemany, Jeffrey Crawford, Laura K. Pomerenke, Samuel J. Wang, Paul D. Crossan, Dustin E. Stevenson, Lisa R. Korff, Richard S. Hudes, Julie E. Lang, James J. Vopal, Joshua Lukenbill, Sarah P. Cate, Raymond Thertulien, Janice N. Kim, Kurt Oettel, Jack J. Hong, Deborah A. Lue, Hong Zhao, Timothy E. Byun, Donald F. Busiek, Helen A. Pass, Laura S. Dominici, Timothy A. Goedde, Puja Nistala, Lynn J. Howie, Elise Gates, Alison K. Conlin, Steven R. Bonin, Robert D. Siegel, Jeannie Shen, Jonathan D. Grant, Nicholas DiBella, Ron S. Smith, Donald B. Wender, Michelle Sowden, Bruce G. Haffty, Lisa S. Wang, Shayna L. Showalter, Archie W. Wright, Ki Y. Chung, Luis Baez-Diaz, Steven E. Sckolnik, Lee M. Zehngebot, Ranveer Nand, Jillian M. Lloyd, James E. Liebmann, Fiona N. Denham, Honnie R. Bermas, Daniel Arsenault, Donna L. Dyess, Scott P. Albert, M. G. Fort, Ronda S. Henry-Tillman, Eric A. Brown, Robert H. Liebross, Philip E. Lammers, Paul H. Schmidt, Sanjeev Sharma, Kara L. Leonard, Candice A. Sauder, Shaker R. Dakhil, Dean J. Conterato, Daniel D. Kirchoff, Victor G. Vogel, Erica V. Bloomquist, Seth A. Kaufman, Caroline J. McGugin, Samantha A. Seaward, Mark E. Bernard, Brian D. Stoll, Courtney A. Jensen, Keith S. Lanier, Joseph J. Weber, Jamie L. Wagner, Catherine E. Pesce, Jana L. Fox, Michael P. Alexander, Elke Aippersbach, Lisa M. Lai, Ruby A. Grimm, Elizabeth M. Nichols, Nasfat Shehadeh, Madhu Chaudhry, Danielle M. Bertoni, Rebecca K. Viscusi, Ingrid M. Lizarraga, Ann M. Leitch, Jon M. Greif, Charlie C. Pan, Courtney A. Vito, Ann M. Mauer, Uzair B. Chaudhary, Lori Schleicher, Leah Bassin, Edward R. Sauter, Bret Taback, Daniel M. Anderson, Lisa D. Yee, Eric C. Feliberti, James L. Wade, Benjamin T. Marchello, Monica Morrow, Gary W. Unzeitig, Leslye L. Ingersoll, Toan T. Nguyen, Amy E. Rivere, William C. Dooley, Elyse A. Lambiase, Elizabeth Cathcart-Rake, Anthony J. Jaslowski, Harvey E. Einhorn, Katherine L. Glover-Collins, Mark V. Mishra, Richard C. Frank, Jodi L. Brehm, Kari M. Rosenkranz, Christina M. Casteel, Lisa K. Jacobs, Susanna Hong, Elizabeth A. Mittendorf, Michelle M. Fillion, Richard D. Lovett, Richard L. White, Vivek S. Kavadi, Richard L. Deming, Chantal R. Reyna, Lucas Wong, James M. Granfortuna, Mark F. Kozloff, Armando E. Giuliano, Erika L. Rager, Pavani Chalasani, Robert R. Kohl, Tara M. Balija, Nakhle S. Saba, Edmund W. Tai, Esther H. Rehmus, Andrew S. Camarata, Michel R. Hurtubise, Yallapragada S. Rao, Oh-Hoon Kwon, William P. Fusselman, Lisa Wiechmann, Joella E. Wilson-Dagar, Mohammed Amine Achhal El Kadmiri, Richard J. Barth, Susan E. Lyons, Muhammad Salim, Roderick S. McKee, Heidi C. Memmel Mitidiero, Andrea B. McKee, Jennifer L. Marti, Ayemoethu Ma, Steven Latosinsky, Christine A. Koch, Sheena K. Jain, Robert C. Gabordi, Lydia T. Komarnicky, Rakesh Gaur, Christine Lambert, Lisa R. Spiguel, Pam G. Khosla, Fahima A. Osman, Maria T. Grosse-Perdekamp, Christine Desbiens, Lydia W. Choi, Amit B. Shah, Anuradha B. Chakravarthy, Mohamed Ali M. Akra, Maria R. Tria Tirona, Sharad A. Ghamande, Mark Basik, Angel Arnaout, Heather R. Macdonald, Rakhshanda L. Rahman, Christiaan S. Stevens, Kendal P. Dixon, Marissa M. Howard-M cNatt, Mindy W. Bowie, Giles Fort, Elizabeth Min Hui Kim, Manmeet Malik, Sylvia V. Velinova Falls, Michael R. Cassidy, Zsolt Gabos, Frances C. Wright, Kathleen J. Yost, John A. Ellerton, Lucas Sideris, Ursa A. Brown-Glaberman, James H. Feusner, Vinay K. Gudena, William E. Burak, John A. Keech, Hanadi BuAli, Mohamed A. Akra, Farah Naz, Aye M. Ma, William Tse, Eleftherios (Terry) P. Mamounas, Elizabeth C. Reed, Hannah W. Hazard, V. S. Klimberg, Hannah W. Hazard-Jenkins
Related Therapeutic Areas
Sponsors
Collaborators: Canadian Cancer Trials Group, National Cancer Institute (NCI)
Leads: Alliance for Clinical Trials in Oncology

This content was sourced from clinicaltrials.gov

Similar Clinical Trials