Long-Term Chamomile Therapy for Generalized Anxiety Disorder (GAD)
Status: Completed
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
Prior research has shown that chamomile may be an effective, short-term anti-anxiety treatment. This study will examine the initial and long-term benefits of chamomile extract therapy for the prevention of recurrent anxiety disorder.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: No
View:
• Men and women at least 18 years old (all races and ethnicity)
• DSM IV diagnosis of GAD as the primary anxiety disorder
• Baseline GAD-7 score ≥ 10
• Baseline CGI/S score at least 4
• Not taking anti-anxiety medication (e.g., Benzodiazepines, buspirone, antidepressants)
• Not taking antidepressant, mood stabilizer, or tranquilizer therapy for a prior DSM IV Axis I mood disorder that is in remission
• Able to understand and provide informed consent
• Able to participate in a 38-week study
Locations
United States
Pennsylvania
Depression Research Unit
Philadelphia
Time Frame
Start Date: February 2010
Completion Date: June 2015
Participants
Target number of participants: 180
Treatments
Experimental: Chamomile Extract
Pharmaceutical grade oral chamomile extract.
Placebo Comparator: Placebo
Pharmaceutical grade lactose monohydrate.
Authors
Related Therapeutic Areas
Sponsors
Leads: University of Pennsylvania