Endoscopic Buccal Mucosal Graft Urethroplasty or Bladder Neck Reconstruction

Who is this study for? Patients with Urethral Stricture
What treatments are being studied? Direct Vision Internal Urethrotomy Treated with Liquid Buccal Mucosal Graft
Status: Unknown status
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

Study Objectives The current definitive treatment options for urethral stricture disease include endoscopic urethrotomy known as Direct Vision Internal Urethrotomy (DVIU) or open reconstruction known as urethroplasty (1-6). The purpose of this study is to determine feasibility of endoscopic-only repair of urethral stricture or bladder neck contracture using a combination of existing surgical techniques of internal urethrotomy (or bladder neck incision) augmented by buccal mucosal graft.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: No
View:

• Male >18 years of age

• bulbar urethral stricture

• bladder neck contracture

Locations
United States
New York
SUNY Upstate Medical University
Syracuse
Contact Information
Primary
Dmitriy Nikolavsky, MD
nikolavd@upstate.edu
315-464-1500
Backup
Janice Sell
sellj@upstate.edu
315-464-6114
Time Frame
Start Date: February 2017
Completion Date: October 2021
Participants
Target number of participants: 10
Treatments
Experimental: liquid buccal mucosa graft
DVIU treated with liquid buccal mucosal graft; endoscopic injection of morcellated buccal mucosal graft mixed with fibrin glue
Related Therapeutic Areas
Sponsors
Leads: State University of New York - Upstate Medical University

This content was sourced from clinicaltrials.gov

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