Improving Clinical PET/CT Image Quality in Retrospectively Reconstructed Breath-Hold Images

Status: Terminated
Location: See location...
Intervention Type: Other
Study Type: Observational

The patient has been referred for an FDG PET/CT scan. FDG is a form of sugar that contains a small amount of radioactivity; it is used to see the size and possible spread of cancer in the body. Pictures of the body are taken on a machine called a PET/CT scanner. The purpose of this current study is to see if we, the investigators, can take clearer pictures of the tumor than we could with our routine scan method. This would allow us to better see how FDG is picked up by the tumor. PET/CT is presently one of the best tools for detecting cancer and determining its spread in the body. However, due to breathing motion, PET and CT images may become blurred and the location of the tumor on CT and PET images may not match. We have developed a new method that enables us to reduce image blurring and to measure the tumor more accurately on PET images. In this study we want to compare two kinds of images: those from the standard PET/CT scan, and the PET/CT scan pictures taken with our new method. If successful, we may use this new method for clinical routine in the future.

Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No

• Participant is capable of providing written consent.

• 18 years of age or older.

• Patient with a known or suspected FDG-avid malignancy in the torso

United States
New York
Memorial Sloan-Kettering Cancer Center
New York
Time Frame
Start Date: April 2010
Completion Date: March 2012
Target number of participants: 6
Breath-Hold PET/CT image
In addition to the standard clinical PET/CT images, we will provide a breath-hold PET/CT image set, using the same PET data for both.
Related Therapeutic Areas
Leads: Memorial Sloan Kettering Cancer Center

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