Research Tissue Bank

Status: Completed
Location: See all (11) locations...
Study Type: Observational
SUMMARY

This study that will allow for the preservation and/or storage of a small portion one or more of the following tissues: Peripheral blood Bone marrow Bone marrow biopsy A phlebotomized unit of blood Spleen cells Toenail clippings This material will be used for the study of Myeloproliferative Disorders (MPD) by researchers. The goals of this research study are to understand the causes of MPDs, how to diagnose them more easily and how to treat them better. MPD is a disease affecting hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These stem cells grow in the center portion of the bones called bone marrow. Under some conditions, these cells are also found in blood. There are several diseases, which are classified as MPD. These include polycythemia vera (too many red blood cells), essential thrombocythemia (too many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in the bone marrow). These syndromes carry a high risk of developing leukemia. It is important to continue to learn more about these blood cancers and to learn more about the effectiveness and potential side effects of various treatments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:

• Patients diagnosed with Philadelphia chromosome negative myeloproliferative disorders (MPD) polycythemia vera (PV), idiopathic myelofibrosis (IM), and essential thrombocythemia (ET) are eligible.

• Newly diagnose MPD patients as well as previously treated for a MPD are eligible.

• Signed informed consent is required from each patient at the time of enrollment.

Locations
United States
California
Palo Alto Medical Foundation Research Institute
Palo Alto
Washington, D.c.
University of Georgetown
Washington
Weill Cornell University
Washington
Illinois
University of Illinois at Chicago
Chicago
Maryland
Johns Hopkins
Baltimore
New York
Roswell Park
Buffalo
Mount Sinai Medical Center
New York
Pennsylvania
University of Pennsylvania
Philadelphia
Utah
University of Utah
Salt Lake City
Other Locations
Italy
Ospedali Riuniti di Bergamo
Bergamo
University of Florence
Florence
Time Frame
Start Date: September 2007
Completion Date: March 27, 2017
Participants
Target number of participants: 963
Sponsors
Collaborators: Myeloproliferative Disorders-Research Consortium, National Cancer Institute (NCI)
Leads: Icahn School of Medicine at Mount Sinai

This content was sourced from clinicaltrials.gov

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