The Validity of the Quick Renal MRI in Pediatric Kidney Disease

Trial Information
Status: Suspended
Location: See location...
Intervention Type: Diagnostic Test
Study Type: Interventional
Study Phase: Not Applicable

The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology. Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).

Am I eligible for this trial?
Participation Requirements
Maximum Age:
Healthy Volunteers:

• Aim 1:

• Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis

• Undergoing clinical DMSA scan

• Aim 2:

• Undergoing DMSA scans as a part of their routine clinical care

• History of more than one UTI in the past year

Where is this trial taking place?
United States
American Family Children's Hospital
When is this trial taking place?
Start Date: May 7, 2019
Completion Date: May 2023
How many participants will be in this trial?
Target number of participants: 100
What treatment is being studied in this trial?
Other: DMSA/Quick MRI
All participants will go through DMSA and Quick MRI scan to help determine the validity of the Quick Renal MRI in pediatric kidney disease.
Who are the authors of this trial?
Ruthie Su
What other conditions are being studied in this trial?

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