A Prospective Study of Pregnant and Postpartum Women With and Without Mood Disorders

Trial Information
Status: Recruiting
Location: See location...
Study Type: Observational
Summary

This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes. Participants will have psychiatric histories taken and will be monitored throughout pregnancy and during the postpartum period for the development of depressive or other mood episodes. Biological measures, including hormone levels, immunological measures, and growth factors will be collected. Environmental factors such as sleep deprivation and stress will also be measured. These factors will be considered in the setting of genetic and epigenetic data with the hope that investigators will ultimately be able to predict the onset of postpartum mood episodes in this vulnerable population.

Am I eligible for this trial?
Participation Requirements
Sex:
All
Minimum Age:
18
Maximum Age:
50
Healthy Volunteers:
Accepts Healthy Volunteers

• Pregnant women with singleton pregnancies

• With or without a history of a mood disorder (MDD, Bipolar I, Bipolar II or Bipolar NOS)

Where is this trial taking place?
United States
Maryland
550 North Broadway
Recruiting
Baltimore
Who do I contact about this trial?
Primary
Jennifer Payne, MD
jpayne5@jhmi.edu
410-502-0050
When is this trial taking place?
Start Date: October 1, 2017
Estimated Completion Date: October 2022
How many participants will be in this trial?
Target number of participants: 400
What treatment is being studied in this trial?
Pregnant women with Mood Disorders
Pregnant women with a history or current diagnosis of Major Depressive Disorder or Bipolar Disorder
Healthy controls
Pregnant women without a history or current diagnosis of a mood disorder.
Who are the authors of this trial?
Jennifer Payne

This content was sourced from clinicaltrials.gov

An Endocrine Model for Postpartum Mood Disorders
Who is this study for:Patients with postpartum mood disorders
Status:Recruiting
Start Date:April 26, 1996
Study Drug:Estradiol+Progesterone
Study Type:Other, Drug
Phase: Phase 2