Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme Response to Treatment With Bevacizumab for Progressive Disease

Status: Completed

Location: See location...

Intervention Type: Radiation

Study Type: Observational

SUMMARY

This study is for subjects with a diagnosis of a brain tumor called glioblastoma that is being treated with bevacizumab. This study will use a new MRI technique to compare the images of blood vessels and tumor structure to the effectiveness of bevacizumab.

Eligibility

Participation Requirements

Sex: All

Minimum Age: 18

Maximum Age: 80

Healthy Volunteers: No

View:

• Age between 18 and 80 years of age

• Progressive glioblastoma patients who have been planned to receive bevacizumab

• Karnofsky Performance Status 50 or above (vd. Appendix A)

• Established pathologic diagnosis of glioblastoma

• Prior treatment with radiation and chemotherapy