NINDS Clinical Research Collaboration Chronic Migraine Treatment Trial

Status: Completed
Location: See all (39) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: Accepts Healthy Volunteers
View:

• History of chronic migraine for at least 6 months

• Age ≥ 18 years and age of migraine onset 60 or younger

• EKG performed in the last 12 months

Locations
United States
Arizona
Mayo Clinic 5777 E Mayo Blvd
Phoenix
Paradigm Clinical, Inc. 1324 W. Prince Rd
Tuscon
California
Dr. Stephen David Forner - 1405 Magnolia Avenue, Suite B
Chico
Shanti Clinical Trials, 1880 West Washington Street
Colton
NervPro Research, 15825 Laguna Canyon Road, Suite 202
Irvine
Mercy Medical Group- CHWMF 3000 Q Street, Neurology
Sacramento
Florida
Health Sciences America, LLC, 1515 N Federal Hwy, Suite 105
Boca Raton
Southeast Clinical Research, LLC, 304 NE 1st Street
Chiefland
Scientific Clinical Research, Inc 1065 NE 125th Street , Ste 417
Miami
Neurology Associates of Ormond Beach 8 Mirror Lake Drive Suite A&B
Ormond Beach
Neurologique Foundation, Inc. 6 Fairfield Blvd. Suite 11
Ponte Vedra
Neurology Clinical Research, Inc, 3540 North Pine Island Rd
Sunrise
Georgia
Dr. B. Abraham, P.C. 3020 Highway 124
Snellville
Indiana
Ft. Wayne Neurological Center 7956 W. Jefferson Blvd.
Ft. Wayne
Kansas
MidAmerica Neuroscience Research Foundation, 8550 Marshall Dr, Suite 100
Lenexa
Kentucky
Trover Health System Center for Clinical Studies, 200 Clinic Drive
Madisonville
Massachusetts
New England Center for Clinical Research (NECCR), 52 Brigham St #7
New Bedford
New England Regional Headache Center, Inc 85 Prescott St, Ste 101
Worcester
Michigan
ClinSite, LLC 24 Frank Lloyd Wright Drive, Lobby M
Ann Arbor
North Carolina
Mission Neurology, Research Institute Mission Hospital, 509 Biltmore
Asheville
Guilford Neurologic Associates, 1126 North Church Street, Suite 200
Greensboro
New Jersey
Anderson & Collins Clinical Research 1 Ethel Road, Suite 106B
Edison
New York
Dent Neurologic Institute, 3980 Sheridan Drive
Amherst
Montefiore Headache Center 1575 Blondell Avenue Ste 225
Bronx
Island Neurological Associates, PC, 824 Old Country Road
Plainview
Schenectady Neurological Consultants 1401 Union Street
Schenectady
Ohio
ClinExcel Research 7908 Cincinnati-Dayton Rd, Ste J
West Chester
Pennsylvania
Abington Neurological Associates, Ltd., 1245 Highland Avenue, Ste 301
Abington
Neurology and Sleep Medicine PC, 701 Ostrum Street, Suite 302
Bethlehem
Jefferson Headache Center/Thomas Jefferson Univ. 111 South 11th Street, Suite 8130
Philadelphia
Tennessee
Progress Clinical Trials, 707 Kings Lane
Tullahoma
Texas
Texas Neurology, PA, 6301 Gaston Avenue, Suite 400 West Tower
Dallas
Houston Headache Clinic, 1213 Hermann Drive, Suite 820
Houston
Houston Sleep Center, Todd J. Swick, MD, PA, 7500 San Felipe, Suite 525
Houston
Protenium Clinical Research, LLC 1725 Chadwick Court Suite 200
Hurst
Utah
Starlight Clinical Research, 1325 W. South Jordan Pkwy, Ste 101
South Jordan
Washington
Swedish Pain & Headache Center 101 Madison St, Suite 200
Seattle
Wisconsin
Gundersen Clinic, Ltd, 1836 South Avenue, MS: EB3-002
La Crosse
West Virginia
West Virginia University 1 Medical Center Dr, Box 9180
Morgantown
Time Frame
Start Date: October 2008
Completion Date: September 2010
Participants
Target number of participants: 191
Treatments
Active Comparator: 1
Participants will receive propranolol and topiramate.
Placebo Comparator: 2
Participants will receive a placebo and topiramate.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS), Ortho-McNeil Janssen Scientific Affairs, LLC
Leads: Anne Lindblad

This content was sourced from clinicaltrials.gov

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