An Initial Study of FDG-PET/CT and MRI to Assess Thymic Function

Status: Completed
Location: See all (4) locations...
Intervention Type: Device
Study Type: Observational

The purpose of this study is to see if a positron emission tomography/computed tomography (PET/CT) scan and a magnetic resonance imaging (MRI) of the chest can assess changes in the thymus size and function. The researchers would like to monitor the thymus with a PET/CT scan and a MRI before and after the participants transplantation.

Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: No

• Patient's age is ≥18 or ≤65 years old.

• Patients must have a plan to receive a CD34-selected peripheral blood stem cell graft.

United States
New Jersey
Memorial Sloan Kettering Cancer Center
Basking Ridge
New York
Memorial Sloan-Kettering Cancer Center at Commack
Memorial Sloan Kettering Westchester
Memorial Sloan Kettering Cancer Center
New York
Time Frame
Start Date: August 2016
Completion Date: January 2020
Target number of participants: 3
PET/CT scans and MRI
Eligible patients will be enrolled onto the study, and will undergo 3 limited field of view (FOV) FDG-PET/CT scans and MRI of the chest: at baseline (within 4 weeks prior to transplantation), and approximately 3 months (+/-2 weeks) and 6 months (+/-2 weeks) after transplant. PET/CT and MR imaging can be completed on the same day. We will also offer the exams on other days if this is easier for the patient. The PET/CT and MR should be performed within 2 weeks of each other.
Leads: Memorial Sloan Kettering Cancer Center

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