Cortico-saving Treatments Proposed for CLIPPERS (Chronic Lymphocytic Inflammation With Pontine Perivascular Responsive to Steroids): a First Cohort
Status: Terminated
Location: See all (11) locations...
Intervention Type: Other
Study Type: Observational [Patient Registry]
SUMMARY
The primary objective of this study is to collect information about how CLIPPERS patients are currently being treated in France.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: No
View:
• Patient correctly informed about the study
• Symptoms and/or clinical signs indicating that the brain stem is affected
• MRI shows punctate gadolinium highlights and/or curvilinear bridge and/or middle cerebellar peduncles
• Clinical and radiological cortico sensitivity
• If a cerebral biopsy has been performed, presence of a lymphocytic, histiocytic or lympho-hysticytic infiltrate
Locations
Other Locations
France
CHU de Bordeaux - Groupe Hospitalier Pellegrin
Bordeaux
CH de Dax - Côte d'Argent
Dax
CHU de Limoges - Hôpital Dupuytren
Limoges
APHM - Hôpital La Timone Adultes
Marseille
CHU de Montpellier - Hôpital Saint-Eloi
Montpellier
CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes Cedex 9
CHU de Rouen - Hôpital Charles Nicolle
Rouen
CHRU de Strasbourg - Hôpital Civil
Strasbourg Cedex
CHRU de Toulouse - Hôpital de Rangueil
Toulouse Cedex 9
CHRU de Toulouse - Hôpital Purpan
Toulouse Cedex 9
CHRU de Tours - Hôpital Bretonneau
Tours
Time Frame
Start Date: March 25, 2015
Completion Date: March 25, 2016
Participants
Target number of participants: 3
Treatments
CLIPPERS patients
The population concerned by this study consists of patients diagnosed according to CLIPPERS criteria (see inclusion and exclusion criteria).~Intervention: Data entry
Authors
Dominique Figarella Branger, Sandrine Eimer, Elsa Kaphan, David Maltete, Pierre Labauge, Eric Thouvenot, Guillaume Taieb, David Brassat, Stephane Kremer, Laurent Magy, Michel Clanet, Jérome de Sèze, Romain Lefaucheur, Christine Tranchant, Giovanni Castelnovo, Jean Pelletier, Thierry Vincent, Bertrand Audoin, Nadège Limousin, Patrice Desbordes, Emmanuelle Uro-Coste, Dimitri Renaud, Nicolas de Champfleur
Sponsors
Leads: Centre Hospitalier Universitaire de Nīmes