Impact of Valproate on Angiogenesis and Histone Deacetylation in Bladder Cancer
The goal of this study is to test whether the drug valproic acid can cause changes in bladder tumors that might inhibit their growth.
• Patient over the age of 21
• Bladder tumor suspected or confirmed
• ECOG status 0 to 2
• Premedication Lab values:
• Absolute Neutrophil Count >750 cells/m3 AST/ALT less than 1.5xN Amylase less than 1.5xN Platelet Count > 125,000 PT/PTT > 1.3xN Hemoglobin > 8gm/dL Creatinine less than 1.5xN