Photobiomodulation Therapy With Different Wavebands for Hair Loss: A Systematic Review and Meta-Analysis.

Journal: Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.]
Treatment Used: Photobiomodulation Therapy
Number of Patients: 966
MediFind Summary

Summary: This review of the literature assessed the effect of photobiomodulation therapy for patients with hair loss.

Conclusion: For patients with hair loss, photobiomodulation therapies are effective.


Background: Photobiomodulation is a promising therapy for hair loss with negligible side effects. However, the reported effects of photobiomodulation therapy for hair loss are inconsistent.

Objective: To assess the curative effect of photobiomodulation therapy for the treatment of hair loss.

Methods: A systematic review of self-controlled studies and randomized controlled trials was conducted. ScienceDirect, PubMed, and Wiley Online Library were searched from the earliest date to May 30, 2021.

Results: Thirty-six studies (966 patients) were included. Two to 4 meta-analyses with different indices were performed separately on 4 groups of studies to test the effectiveness of the following hair loss treatments: ultraviolet light for alopecia areata (AA), red light for androgenetic alopecia (AGA), infrared light for AA, and infrared light for AGA. All meta-analyses showed that treatments were superior to control ( p < .05).

Conclusions: The meta-analyses strongly suggested that photobiomodulation therapies with ultraviolet and infrared light were effective for treating AA, and photobiomodulation therapies with red light and infrared light were effective for treating AGA.

Yuehou Zhang, Jianlong Su, Kui Ma, Xiaobing Fu, Cuiping Zhang

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