Low-Dose Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
Status: Recruiting
Location: See location...
Intervention Type: Radiation, Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: f
View:
• Patient at Mayo Clinic, Rochester, MN
• Age 50 years or older
• Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
• Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
• Ability to complete study questionnaires
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Department of Medicine Research Hub
DOMResearchHub@mayo.edu
507-266-1944
Time Frame
Start Date: 2025-12-19
Estimated Completion Date: 2027-10-01
Participants
Target number of participants: 165
Treatments
Experimental: Low-dose radiotherapy (LDRT)
Subjects will receive a total of six (6) low-dose radiotherapy (LDRT) treatments for hand osteoarthritis.
Active_comparator: Corticosteroid injection (CSI)
Subjects will receive standard of care corticosteroid injection (CSI) therapy for hand osteoarthritis.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic