European Study of Cerebral Aspergillosis Treated With Isavuconazole

Trial Information
Status: Recruiting
Location: See location...
Study Type: Observational

Study clinical context Cerebral aspergillosis (CA) is a rare location of invasive aspergillosis (IA), associated with a high morbidity and mortality. Since 2002, voriconazole is the recommended first line treatment of invasive aspergillosis. More recently, isavuconazole appeared to be not less effective than voriconazole in the treatment of filamentous IFI, with a better tolerance profile. The investigators aim to evaluate better the efficacy and the safety of isavuconazole in the treatment of cerebral aspergillosis by a descriptive, multicentric, international retrospective cohort study.

Am I eligible for this trial?
Participation Requirements
Healthy Volunteers:

• Proven or probable cerebral aspergillosis according to the EORTC criteria modified by adding diabetes in the host criteria

• In child or adult

• Treated by isavuconazole at least 7 days

• Diagnosed between March 2017 and June 2020

Where is this trial taking place?
Other Locations
Hôpital Necker-Enfants Malades
Who do I contact about this trial?
Fanny Lanternier, MD
01 44 49 52 62
When is this trial taking place?
Start Date: August 1, 2021
Estimated Completion Date: March 1, 2023
How many participants will be in this trial?
Target number of participants: 40
Who are the authors of this trial?

This content was sourced from

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