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Last Updated: 02/19/2023

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Real-World Evaluation of Eko Algorithms in a Point of Care Setting

Summary: The purpose of this research is to prospectively test and validate the utility of Eko AI plus EMAS (Eko Murmur Analysis Software) in a real world, point-of-care setting.

The Effect of Pulsed-field and Radiofrequency Ablation for Atrial Fibrillation on Platelet Activity, Coagulation and Inflammation

Summary: The aim of the study is to compare platelet activation, activation of the coagulation and inflammation cascade during catheter ablation for atrial fibrillation using radiofrequency or pulsed-field energy. Patients with atrial fibrillation and standard indication for ablation according to the current guidelines will be randomized to ablation either using radiofrequency of pulsed-field energy. The e...

The Investigation and Analysis of Atria of Patients With Non-paroxysmal Atrial Fibrillation Using High-desnity Mapping and Cardiac Magnetic Resonance Imaging

Summary: Cather ablation of non-paroxysmal atrial fibrillation is less effective compared to paroxysmal atrial fibrillation. Therefore, new techniques have been developed, such as high-density mapping to determine areas of focal and rotational activities. The aim is to assess the clinical efficacy of ablation focal and rotational activities, and to assess the relation between the areas of focal and rotatio...

Real-World Evaluation of Eko Murmur Analysis Software in a Point of Care Setting

Summary: The purpose of this research is to prospectively test and validate the utility of Eko AI plus EMAS murmur characterization in algorithm in a real world, point-of-care setting.

Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial Fibrillation (IMPRESSION)

Objective: To evaluate the efficacy and safety of intensive management of blood pressure and cholesterol. Study design: This study is a multi-center, randomized and controlled clinical trial with four equally sized treatment groups: amlodipine/atorvastatin (5/10mg tablet); amlodipine/atorvastatin (5/20mg tablet); amlodipine/atorvastatin (5/10mg tablet)+allisartan (240mg/tablet); amlodipine/atorvastatin (5/20...

EMPOWER-1: A Multi-site Clinical Cohort Study to Reduce Health Inequality: Identifying Ethnic Disparities in Treatment Failures for Medicines Prescribed to Treat Diseases That Cause Significant Mortality and Morbidity in the UK Population

Summary: Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the extent and basis of treatment failure in different patient populations. The vast majority of drug registration clinical trials have under-representation of ethnic minority pop...

Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery

Summary: The goal of this interventional clinical trial is compare between two different dose regimens of bisoprolol (beta-blocker) in CABG patients in terms of efficacy and safety.

STOP AF First Post-Approval Study, an Addendum to the Cryo Global Registry

Summary: The STOP AF First PAS is a prospective, global, multi-center, observational trial.

Strategies for Catheter Ablation of Persistent Atrial Fibrillation: a Randomized, Comparative Study

Summary: The objective of this study is to compare the efficacy of three different ablation strategies in patients with persistent AF: PV antral isolation alone (PVAI) PV antral isolation plus ablation of drivers (PVAI+drivers) PV antral isolation plus isolation of posterior wall (PVAI+box) All three strategies will employ contemporary catheter ablation technology using more efficient open irrigated tip co...

STOP Persistent AF Post-Approval Study, a Sub-study to the Cryo Global Registry

Summary: The STOP Persistent AF Post Approval Study (PAS) is a prospective, global, multicenter, observational trial.

A Pilot Randomized Study of the Use of The Sentinel Device for Cerebral Protection During Atrial Fibrillation Ablation

Summary: The purpose of the study is to see if the Sentinel® Cerebral Protection System may prevent occurrence of stroke during an ablation procedure for atrial fibrillation (AF). The secondary purpose of this study is to study if cognitive function after AF ablation differs between those treated with the Sentinel cerebral protection device and those who do not receive the device.

Cryo Global Registry, a Part of the Medtronic Cardiac Ablation Post-Market Study Platform

Summary: Cryo Global Registry a prospective, global, multi-center, observational Post-Market Registry

Showing 1-12 of 576

Last Updated: 02/19/2023