Validity of Parametric MRI Using VIRAD Scoring in the Diagnosis of Cancer Bladder
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Our aim in this prospective study is to evaluate the validity of the non-contrast biparametric MRI (bp-MRI), including T2-WI and DWI sequences, and the availability of an alternative to the mp-MRI, for the muscle invasiveness assessment of bladder cancer using VIRAD scoring in both techniques.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• 58 cases of patients who suspected to have cancer urinary bladder by clinical, histopathological examination and radiological imaging.
• All age groups . Both sex
Locations
Other Locations
Egypt
Assuit university
RECRUITING
Asyut
Contact Information
Primary
Hassan Megally, proff
hasanibrahim48@yahoo.com
01006209584
Backup
Marwa Makboul, lecturer
makboul@aun.edu.eg
0100654159
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 58
Treatments
Experimental: mpMRI and biparametric MRI
MRI images of the 58 patients with bladder tumors were transferred to a picture archiving communication system (PACS). The images were separated into two groups, namely set 1 (bp-MRI (non-contrast) protocol) and set 2 (mp-MRI protocol). Set 1 images has included three planes T2-WI and axial DWI sequences; set 2 images has included the DCE sequence in addition to set 1. Both of image sets were independently evaluated by a board-certified abdomi nal radiologist with 10 years of experience (reader 1) and general radiologist with 8 years of experience (reader 2). All lesions is scored in accordance with VI-RADS criteria in T2-WI, DWI, and DCE images separately, and the final VI-RADS score was determined. The lesions with VI-RADS scores 1-3 were evaluated as NMIBC, and VI-RADS scores 4 and 5 as MIBC .
Related Therapeutic Areas
Sponsors
Leads: Assiut University