Bullous pemphigoid is a skin disorder characterized by blisters.
Bullous pemphigoid is an autoimmune disorder that occurs when the body's immune system attacks and destroys healthy body tissue by mistake. Specifically, the immune system attacks the proteins that attach the top layer of skin (epidermis) to the bottom layer of skin.
This disorder usually occurs in older persons and is rare in young people. Symptoms come and go. The condition often goes away within 5 years.
In some cases, the condition is triggered by a medicine.
Most people with this disorder have itchy skin that may be severe. In most cases, there are blisters, called bullae.
Anti-inflammatory medicines called corticosteroids may be prescribed. They may be taken by mouth or applied to the skin. More powerful medicines may be used to help suppress the immune system if steroids do not work, or to allow lower steroid doses to be used.
Antibiotics in the tetracycline family may be useful. Niacin (a B complex vitamin) is sometimes given along with tetracycline.
Your provider may suggest self-care measures. These may include:
Janet Fairley is a Dermatologist in Iowa City, Iowa. Dr. Fairley has been practicing medicine for over 41 years and is rated as an Elite doctor by MediFind in the treatment of Bullous Pemphigoid. She is also highly rated in 24 other conditions, according to our data. Her top areas of expertise are Bullous Pemphigoid, Pemphigus, Pemphigus Vulgaris, and Pemphigus Foliaceus. She is licensed to treat patients in Iowa and Wisconsin. Dr. Fairley is currently accepting new patients.
Pascal Joly is in Rouen, France. Joly is rated as an Elite expert by MediFind in the treatment of Bullous Pemphigoid. They are also highly rated in 22 other conditions, according to our data. Their top areas of expertise are Pemphigus, Pemphigus Foliaceus, Pemphigus Vulgaris, and Bullous Pemphigoid.
Ron Feldman is a Dermatologist in Atlanta, Georgia. Dr. Feldman has been practicing medicine for over 17 years and is rated as an Elite doctor by MediFind in the treatment of Bullous Pemphigoid. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Bullous Pemphigoid, Cicatricial Pemphigoid, Pemphigus Foliaceus, and Pemphigus. He is licensed to treat patients in Georgia. Dr. Feldman is currently accepting new patients.
Bullous pemphigoid usually responds well to treatment. The medicine can often be stopped after several years. The disease sometimes returns after treatment is stopped.
Skin infection is the most common complication.
Complications resulting from treatment may also occur, especially from taking corticosteroids.
Contact your provider if you have:
Published Date : April 14, 2021
Published By : Elika Hoss, MD, Senior Associate Consultant, Mayo Clinic, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Dinulos JGH. Vesicular and bullous diseases. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 16.
Peña S, Werth VP. Bullous pemphigoid. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson IH, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 33.