Deep Brain Stimulation and Thalamotomy for the Treatment of Dystonia Acquired by Moyamoya Disease with Stroke.

Journal: Tremor And Other Hyperkinetic Movements (New York, N.Y.)
Treatment Used: Deep Brain Stimulation and Thalamotomy
Number of Patients: 1
Published:
MediFind Summary

Summary: The study researched the safety and effectiveness of deep brain stimulation and thalamotomy in patients with dystonia acquired by moyamoya disease with stroke.

Conclusion: Deep brain stimulation and thalamotomy may be potentially beneficial treatments for dystonia acquired by moyamoya disease with stroke.

Abstract

Background: Moyamoya disease (MMD) is a type of chronic cerebrovascular disease. Currently, revascularization surgery including direct/indirect procedure is recommended for symptomatic patients. However, some patients still respond poorly to the treatment or develop secondary symptoms. Case report: We report the first case of an MMD patient treated with deep brain stimulation (DBS) and thalamotomy. Symptoms of dystonia due to hemorrhage in the thalamus responded poorly to revascularization surgery, but were considerably alleviated by stereotactic neurosurgery. Discussion: Our case report provides a potential strategy for management of refractory symptomatic MMD patients with dystonia and also supports the combined efficacy of DBS with thalamotomies. Highlights: Approximately 30% of patients with Moyamoya disease (MMD) presenting movement symptoms do not respond well to revascularization surgery. We reported an MMD patient treated with deep brain stimulation (DBS) and thalamotomy with significant dystonia and dystonic tremor symptom amelioration. It indicates that DBS or stereotactic lesioning might be a potential treatment for the refractory movement symptoms of MMD.

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