A Phase 2b Randomized, Double-blind, Placebo-controlled, Parallel-Group Study to Assess Efficacy and Safety of Verekitug (UPB-101) in Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: Recruiting
Location: See all (311) locations...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
The purpose of this study is to assess the efficacy and safety of verekitug (UPB-101) in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), an inflammatory lung disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 85
Healthy Volunteers: f
View:
• Physician diagnosis of COPD for \>12 months.
• Current or former smokers with a smoking history of 10 pack-years or more.
• Post-bronchodilator FEV1/ Forced Vital Capacity (FVC) ratio \<0.70 and predicted post-bronchodilator FEV1 \>30% and ≤80%.
• Modified Medical Research Council dyspnea scale Grade ≥2.
• Background triple therapy (Inhaled Corticosteroid \[ICS\], Long-Acting Beta Agonist \[LABA\], Long-Acting Muscarinic Antagonist \[LAMA\]) for 3 months before randomization with a stable dose of medications for 1 or more months prior to Visit 1.
• Are ≥80% compliant with background therapy during the screening period.
Locations
United States
Arizona
Quality of Life Med Research
WITHDRAWN
Tucson
California
Kern Research Inc.
RECRUITING
Bakersfield
PulmoCrit Associates
NOT_YET_RECRUITING
Encino
Torrance Clinical Research Institute
RECRUITING
Lomita
Dream Team Clinical Research
RECRUITING
Pomona
Apex Clinical Research
NOT_YET_RECRUITING
San Diego
Allianz Research Institute
RECRUITING
Westminster
Colorado
Allianz Research Institute
RECRUITING
Aurora
Florida
D&H Doral Research Center, LLC
RECRUITING
Doral
Qway Research, LLC
RECRUITING
Hialeah
Finlay Medical Research
RECRUITING
Miami
Research Institute of South Florida
RECRUITING
Miami
Florida Institute for Clinical Research,LLC
RECRUITING
Orlando
Georgia
Velocity Clinical Research-Savannah - Internal Medicine
RECRUITING
Savannah
Iowa
The Iowa Clinic
RECRUITING
West Des Moines
Illinois
Christie Clinic, LLC
RECRUITING
Champaign
Maryland
Velocity Clinical Research-Rockville
RECRUITING
Rockville
Chesapeake Clinical Research, Inc
RECRUITING
White Marsh
Minnesota
HealthPartners
RECRUITING
Saint Paul
North Carolina
American Health Research, Inc.
RECRUITING
Charlotte
South Carolina
Velocity Clinical Research, Anderson
RECRUITING
Anderson
SleepMed Inc.
RECRUITING
Columbia
Velocity Clinical Research, Gaffney
RECRUITING
Greenville
Velocity Clinical Research, Spartanburg - Pulmonology
RECRUITING
Spartanburg
Velocity Clinical Research- Union
RECRUITING
Union
Texas
Elligo Health Research, Inc.
RECRUITING
Austin
El Paso Pulmonary Association
RECRUITING
El Paso
Synergy Groups Medical LLC
RECRUITING
Houston
Synergy Groups Medical LLC
RECRUITING
Houston
Victorium Clinical Research
RECRUITING
Houston
Metroplex Pulmonary and Sleep Center
RECRUITING
Mckinney
Synergy Groups Medical LLC
RECRUITING
Missouri City
Virginia
Velocity Clinical Research - Suffolk
RECRUITING
Suffolk
Other Locations
Argentina
CARE - Centro de Alergia y Enfermedades Respiratorias
NOT_YET_RECRUITING
Buenos Aires
Centro Respiratorio Quilmes
NOT_YET_RECRUITING
Buenos Aires
Cli-nica Adventista Belgrano - investigacion
NOT_YET_RECRUITING
Buenos Aires
Consultorios Médicos Dr. Doreski
NOT_YET_RECRUITING
Buenos Aires
Fundacion CIDEA
NOT_YET_RECRUITING
Buenos Aires
Hosp Zonal Espec en Agudos y Cronicos Dr. A. A. Cetrangolo - Intensive Respiratory Care
NOT_YET_RECRUITING
Buenos Aires
IADIN - Research
NOT_YET_RECRUITING
Buenos Aires
Centro de Medicina Respiratoria
NOT_YET_RECRUITING
Concepción Del Uruguay
Clinica Colombo - Cardiology
NOT_YET_RECRUITING
Córdoba
National University of Cordoba - Rusculleda Foundation - Instituto DAMIC
NOT_YET_RECRUITING
Córdoba
Hospital Español de Mendoza
NOT_YET_RECRUITING
Godoy Cruz
Framingham Centro Medico
NOT_YET_RECRUITING
La Plata
Centro Medico CIMEL CHAHIN CHAHIN
NOT_YET_RECRUITING
Lanús
Centro de Investigaciones Medicas Mar del Plata - internal medicine
NOT_YET_RECRUITING
Mar Del Plata
Fundacion Enfisema
NOT_YET_RECRUITING
Mar Del Plata
Fundacion Scherbovsky
NOT_YET_RECRUITING
Mendoza
Clinica Privada Monte Grande S.A
NOT_YET_RECRUITING
Monte Grande
Fundacion Estudios Clinicos (FECLIN)
NOT_YET_RECRUITING
Rosario
Instituto Médico Fundación Grupo Colaborativo Rosario Invest
NOT_YET_RECRUITING
Rosario
IERIM-Instituto de Enfermedades Respiratoria e Investigacion Médica
NOT_YET_RECRUITING
San Juan Bautista
Centro Medico Privado de Reumatologia - Servicio de Reumatología
NOT_YET_RECRUITING
San Miguel De Tucumán
Investigaciones en Patologias Respiratorias
NOT_YET_RECRUITING
San Miguel De Tucumán
Ibamedica
RECRUITING
Santa Fe
CEMER
NOT_YET_RECRUITING
Vicente López
Bulgaria
Specialized Hospital For Active Treatment Of Pulmonary Diseases Sv.Panteleymon EOOD
NOT_YET_RECRUITING
Dupnitsa
Medical Center Pulmo-2018 EOOD
NOT_YET_RECRUITING
Haskovo
Medical Center - Zdrave1
NOT_YET_RECRUITING
Kozloduy
Medical Center Medconsult Pleven, Lovech branch
RECRUITING
Lovech
MEDICAL CENTER HERA EOOD; Office of Pulmonology and Phtisiatrics
NOT_YET_RECRUITING
Montana
Dr. Filip Shterev IAPSMCPP EOOD
NOT_YET_RECRUITING
Plovdiv
Medical Center Etika Ambulatory For Specialized Outpatient Medical Care OOD
RECRUITING
Plovdiv
Multiprofile Hospital for Active Treatment St. Panteleimon - Plovdiv
NOT_YET_RECRUITING
Plovdiv
Medical Center Prolet EOOD - Pulmonary, Allergy Diseases
RECRUITING
Rousse
Specialized Hospital For Active Treatment Of Pneumo-Phthisiatric Diseases Dr. Dimitar Gramatikov-Ruse EOOD
NOT_YET_RECRUITING
Rousse
Diagnostic consultative center 1 -Sliven
NOT_YET_RECRUITING
Sliven
MHAT Sliven to MMA Sofia
NOT_YET_RECRUITING
Sliven
Acibadem City Clinic Tokuda University Hospital EAD
NOT_YET_RECRUITING
Sofia
DCC Convex EOOD
NOT_YET_RECRUITING
Sofia
First Multiprofile Hospital for Active Treatment - Sofia
NOT_YET_RECRUITING
Sofia
Medical Center Excelsior OOD, Base 1
RECRUITING
Sofia
Medical Center Excelsior OOD, Base 2
NOT_YET_RECRUITING
Sofia
Medical Center Hera
RECRUITING
Sofia
National Multiprofile Transport Hospital (NMTB) - Internal Diseases
RECRUITING
Sofia
Specialized Hospital For Active Treatment Of Pulmonary Diseases - Sofia EOOD
NOT_YET_RECRUITING
Sofia
Medical Center for Outpatient Care Preventsia 2000
RECRUITING
Stara Zagora
SHLTTRPD Sveta Petka Balgarska EOOD
RECRUITING
Velingrad
Chile
Bioreuma
NOT_YET_RECRUITING
Concepción
Ctro Respiratorio Integral CENRESIN
NOT_YET_RECRUITING
Quillota
Centro Investigación Maule
NOT_YET_RECRUITING
Talca
Centro de Investigación de Enfermedades Respiratorias e Inmunológicas
NOT_YET_RECRUITING
Viña Del Mar
Centro de Investigaciones Clínicas Viña del Mar
NOT_YET_RECRUITING
Viña Del Mar
Clinica Fundacion Medica San Cristobal
NOT_YET_RECRUITING
Vitacura
Georgia
LTD High Technology Hospital Medcenter
RECRUITING
Batumi
LTD MARNECOR - Internal Medicine
RECRUITING
Marneuli
LTD Clinic Rustavi
NOT_YET_RECRUITING
Rustavi
A. Aladashvili clinic LLC
RECRUITING
Tbilisi
Center of Allergy and Immunology - Allergy/Immunology-Reumatology
RECRUITING
Tbilisi
Ltd Diacor
RECRUITING
Tbilisi
LTD Israel-Georgian Medical Research Clinic Healthycore
RECRUITING
Tbilisi
Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic
RECRUITING
Tbilisi
Germany
Gemeinschaftspraxis Rolke / Rückert
NOT_YET_RECRUITING
Aschaffenburg
Pneumologie, Schlafmedizin und Onkologie am Diako
NOT_YET_RECRUITING
Augsburg
CIMS Studienzentrum Bamberg
NOT_YET_RECRUITING
Bamberg
Lungenpraxis Hohenzollerndamm
NOT_YET_RECRUITING
Berlin
MECS Research GmbH
NOT_YET_RECRUITING
Berlin
Studienpraxis Berlin-Brandenburg
RECRUITING
Berlin
Velocity Clinical Research Germany GmBH
NOT_YET_RECRUITING
Berlin
MECS GmbH
RECRUITING
Cottbus
Pneumostudien Darmstadt GmbH
NOT_YET_RECRUITING
Darmstadt
IKF Pneumologie GmbH & Co. KG
NOT_YET_RECRUITING
Frankfurt Am Main
Pneumologicum-Halle - Pulmonary
NOT_YET_RECRUITING
Halle
ME Clinical Respiratory Research
NOT_YET_RECRUITING
Hamburg
Pneumologische Praxis und Schlaflabor - Lutz Volgmann
NOT_YET_RECRUITING
Hanover
Velocity Clinical Research Germany GmbH
NOT_YET_RECRUITING
Lübeck
IKF Pneumologie GmbH & Co. KG
NOT_YET_RECRUITING
Mainz
Asklepios Lungenklinik Gauting GmbH - Zentrum für Pneumologie und Thoraxchirurgie
NOT_YET_RECRUITING
München
Ballenberger, Freytag, Wenisch
NOT_YET_RECRUITING
Neu-isenburg
Studienzentrum Dr.med. Christian Schlenska - Pneumologie/Allergologie/Innere Medizin
NOT_YET_RECRUITING
Peine
Framol-Med GmbH
NOT_YET_RECRUITING
Rheine
Gemeinschaftspraxis Franz, Weber
NOT_YET_RECRUITING
Witten
Hungary
Aranyklinika Kft
NOT_YET_RECRUITING
Bordány
ClinExpert Kft.
RECRUITING
Budapest
Pulmo Protect Kft.
NOT_YET_RECRUITING
Budapest
Debreceni Egyetem Klinikai Központ - Tüdőgyógyászati Klinika
NOT_YET_RECRUITING
Debrecen
Koch Róbert Kórház és Rendel?intézet
NOT_YET_RECRUITING
Edelény
Farkasgyepui Tudogyogyintezet
NOT_YET_RECRUITING
Farkasgyepű
Erzsebet Gondozohaz Kft.
NOT_YET_RECRUITING
Gödöllő
Bekes Varmegyei Kozponti Korhaz Pandy Kalman Tagkorhaz
NOT_YET_RECRUITING
Gyula
Szalay Janos Rendelointezet
NOT_YET_RECRUITING
Hajdúnánás
Kek Pont Aquagyogyaszat Kft.
RECRUITING
Kecskemét
Infer-Med Kft.
NOT_YET_RECRUITING
Pécs
Puspokladanyi Egeszsegugyi Szolgaltato Nonprotfit Kft
NOT_YET_RECRUITING
Püspökladány
India
JNMC
NOT_YET_RECRUITING
Belgaum
S.P Medical College and Group of Hospitals, Bikaner
NOT_YET_RECRUITING
Bikaner
Shri Mahant Indiresh Hospital
NOT_YET_RECRUITING
Dehradun
Medanta Medicity
NOT_YET_RECRUITING
Gurgaon
Astar Prime Hospitals - Internal Medicine
NOT_YET_RECRUITING
Hyderabad
Rajarshi Chhatrapati Shahu Maharaj (RCSM) Government Medical College & CPR Hospital
NOT_YET_RECRUITING
Kolhāpur
NRS Medical College
NOT_YET_RECRUITING
Kolkata
King George's Medical University
NOT_YET_RECRUITING
Lucknow
Fortis Hospital Mohali
NOT_YET_RECRUITING
Mohali
Shree Hospital & Critical Care Centre
NOT_YET_RECRUITING
Nagpur
A.C. Subba Reddy Government Medical College (ACSR) - Pulmonary
NOT_YET_RECRUITING
Nellore
Sir Ganga Ram Hospital (SGRH) - Gastroenterology and Hepatology
NOT_YET_RECRUITING
New Delhi
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS) - Pandit Bhagwat Dayal Sharma
NOT_YET_RECRUITING
Rohtak
Siddhartha Medical College
NOT_YET_RECRUITING
Vijayawada
Ireland
Cork University Hospital
NOT_YET_RECRUITING
Cork
Our Lady of Lourdes Hospital
NOT_YET_RECRUITING
Drogheda
Connolly Hospital
NOT_YET_RECRUITING
Dublin
St Vincent's University Hospital
NOT_YET_RECRUITING
Dublin
University College Hospital Galway - Pulmonology
NOT_YET_RECRUITING
Galway
University Hospital Limerick
NOT_YET_RECRUITING
Limerick
Tallaght University Hospital
NOT_YET_RECRUITING
Tallaght
Latvia
Daugavpils Regional Hospital
NOT_YET_RECRUITING
Daugavpils
Veselibas Centru apvieniba AS, Dubultu poliklinika
NOT_YET_RECRUITING
Jūrmala
Liepaja Regional Hospital
NOT_YET_RECRUITING
Liepāja
Pauls Stradins Clinical University Hospital - Center of Lung Diseases
NOT_YET_RECRUITING
Riga
SIA Profesora Skrides Sirds klīnika
NOT_YET_RECRUITING
Riga
Lithuania
Hospital of Lithuanian University of Health Sciences Kauno Klinikos
NOT_YET_RECRUITING
Kaunas
Lithuanian University of Health Sciences Kaunas Hospital
NOT_YET_RECRUITING
Kaunas
Republic Klaipeda Hospital
NOT_YET_RECRUITING
Klaipėda
Malaysia
Hospital Pulau Pinang
NOT_YET_RECRUITING
George Town
Institut Perubatan Respiratori
NOT_YET_RECRUITING
Kuala Lumpur
Universiti Malaya Medical Centre
NOT_YET_RECRUITING
Kuala Lumpur
Thomson Hospital Kota Damansara
NOT_YET_RECRUITING
Petaling Jaya
Universiti Teknologi MARA
NOT_YET_RECRUITING
Shah Alam
Mexico
Instituto Jalisciense de Metabolismo, SC - Research
NOT_YET_RECRUITING
Guadalajara
Centro Respiratorio de México
NOT_YET_RECRUITING
México
Hospital Universitario Dr. Jose Eleuterio Gonzalez - CIPTIR
NOT_YET_RECRUITING
Monterrey
Unidad Inv Clinica Medicina
NOT_YET_RECRUITING
Monterrey
Phylasis Clinicas Research S de RL de CV; Sucursal Toluca
NOT_YET_RECRUITING
Toluca
Philippines
De Asis Medical Clinic (Norzel Medical and Diagnostic Clinic)
NOT_YET_RECRUITING
Cebu
Perpetual succour hospital of Cebu INC
NOT_YET_RECRUITING
Cebu
CARE Clinical Trial Group Inc.
NOT_YET_RECRUITING
Dasmariñas
Iloilo Doctors' Hospital Inc.
NOT_YET_RECRUITING
Iloilo City
St. Paul's Hospital of Iloilo Inc. - Pulmonology
NOT_YET_RECRUITING
Iloilo City
Health Cube Medical Clinics
NOT_YET_RECRUITING
Mandaluyong
Marilao Saint Michael Family Hospital, Inc. - Research Room
NOT_YET_RECRUITING
Marilao
Asian Hospital and Medical Center - Medicine
NOT_YET_RECRUITING
Muntinlupa
Lung Center Of the Philippines - Medicine
NOT_YET_RECRUITING
Quezon City
Poland
Centrum Medycyny Oddechowej, Mroz Spolka Jawna
RECRUITING
Bialystok
ClinicMed Daniluk, Nowak Sp. Komandytowa
NOT_YET_RECRUITING
Bialystok
Centrum Medyczne Pratia Bydgoszcz
NOT_YET_RECRUITING
Bydgoszcz
Uniwersyteckie Centrum Kliniczne - Klinika Alergologii
NOT_YET_RECRUITING
Gdansk
Centrum Medyczne Pratia Katowice
NOT_YET_RECRUITING
Katowice
Centrum Medyczne ALL-MED
NOT_YET_RECRUITING
Krakow
Pratia MCM Kraków
NOT_YET_RECRUITING
Krakow
Clinical Best Solutions
NOT_YET_RECRUITING
Lublin
Twoja Przychodnia Nowosolskie Centrum Medyczne Sp. z o. o.
NOT_YET_RECRUITING
Nowa Sól
Specjalistyczna Przychodnia Lekarska Alergo - Med Sp. z o.o.
NOT_YET_RECRUITING
Poznan
EMED Centrum Uslug Medycznych Ewa Smialek
NOT_YET_RECRUITING
Rzeszów
Prywatny Gabinet Lekarski
NOT_YET_RECRUITING
Rzeszów
Velocity Skierniewice Sp. z o.o.
NOT_YET_RECRUITING
Skierniewice
RCMed Oddzial Sochaczew
NOT_YET_RECRUITING
Sochaczew
Twoja Przychodnia Szczecinskie Centrum Medyczne Sp. z o. o.
NOT_YET_RECRUITING
Szczecin
Republic of Korea
The Catholic University of Korea, Incheon St. Mary's Hospital
NOT_YET_RECRUITING
Incheon
Seoul National University Bundang Hospital - Pulmonology
NOT_YET_RECRUITING
Seongnam-si
Eunpyeong St. Mary's Hospital
NOT_YET_RECRUITING
Seoul
Konkuk University Medical Center
NOT_YET_RECRUITING
Seoul
Korea University Anam Hospital - Pulmonology
NOT_YET_RECRUITING
Seoul
Kyung Hee Universtiy Hospital
NOT_YET_RECRUITING
Seoul
Severance Hospital, Yonsei University Health System - Pulmonary
NOT_YET_RECRUITING
Seoul
The Catholic University of Korea, Seoul St. Mary's Hospital - Pulmonology
NOT_YET_RECRUITING
Seoul
Yonsei University, Wonju Severance Christian Hospital - Pulmonology
NOT_YET_RECRUITING
Wŏnju
Romania
Angisan Grup
RECRUITING
Bragadiru
Centrul Medical de Diagnostic si Tratament Ambulator Neomed - Multiple Specialties
RECRUITING
Brasov
Anima Specialty Medical Services
RECRUITING
Bucharest
Centrul Medical Sana
RECRUITING
Bucharest
Medsana CM Cotroceni Pulmonology
NOT_YET_RECRUITING
Bucharest
Rimmed Centru Medical Pulmonology
NOT_YET_RECRUITING
Bucharest
Fundatia Dr. Victor Babes
RECRUITING
Bucuresti
CM Pneumologie Dr Mincu Bogdan
NOT_YET_RECRUITING
Cluj-napoca
Sp Pneumoftizio Leon Daniello CJ
NOT_YET_RECRUITING
Cluj-napoca
Clintrial Medical Center
NOT_YET_RECRUITING
Dobrosloveni
Sp.Clinic Pneumo Constanta Pulmon 2
NOT_YET_RECRUITING
Palazu Mare
Sp Dr Victor Babes Timisoara Pulmon
NOT_YET_RECRUITING
Timișoara
Serbia
Clinical Hospital Center Bezanijska Kosa Clinic for Intern - Pulmology
NOT_YET_RECRUITING
Belgrade
Military Medical Academy
NOT_YET_RECRUITING
Belgrade
MSB General hospital - Clinical Research Center
NOT_YET_RECRUITING
Belgrade
Municipal Institute for Lung Diseases and Tuberculosis - Allegology and Clinical Immunology
NOT_YET_RECRUITING
Belgrade
University Clinical Center of Serbia, Clinic for Pulmonology- IV Department of General Pulmonology
NOT_YET_RECRUITING
Belgrade
Polyclinic Aleksandar Rahec Radojevic
NOT_YET_RECRUITING
Čačak
General Hospital Jagodina/Internal Medicine department
NOT_YET_RECRUITING
Jagodina
nstitute for Pulmonary Diseases of Vojvodina, Clinic for Pulmonary Oncology
NOT_YET_RECRUITING
Kamenitz
University Clinical Center of Kragujevac, Clinic for Pulmonology
NOT_YET_RECRUITING
Kragujevac
Clinical Center Nis,Clinic for Pulmonary Diseases - Pulmonary Diseases & Tuberculosis
NOT_YET_RECRUITING
Niš
General Hospital Uzice, Department for Pulmonology
NOT_YET_RECRUITING
Užice
General Hospital Valjevo - Department for Pulmology
NOT_YET_RECRUITING
Valjevo
Slovakia
FNsP F.D.R. Banska Bystrica - Pneumologie a ftizeologie
NOT_YET_RECRUITING
Banská Bystrica
PAFA, s.r.o.
NOT_YET_RECRUITING
Bratislava
Pneumomed s.r.o. - Pneumo-Alergo Centrum
NOT_YET_RECRUITING
Bratislava
INSPIRO s.r.o. - MUDr. Golubov Alexander - Pneumologia a ftizeologia
NOT_YET_RECRUITING
Humenné
MEDEKA s.r.o. - Pneumologia a ftizeologia
NOT_YET_RECRUITING
Košice
ZAPA JJ s.r.o. - Pneumologia a ftizeologia
RECRUITING
Levice
DIONEA, s.r.o. - Ambul. pneumologie
NOT_YET_RECRUITING
Nové Zámky
Plucna ambulancia Hrebenar s.r.o.
RECRUITING
Spišská Nová Ves
South Africa
Tiervlei Trial Center
NOT_YET_RECRUITING
Bellville
WWCT -Lakeview Hospital
NOT_YET_RECRUITING
Benoni
Canal Walk Clinical Trial Centre
NOT_YET_RECRUITING
Cape Town
Langeberg Clinical Trials
NOT_YET_RECRUITING
Cape Town
Practice Dr Visvakuren Naidoo - Clinical Trials
NOT_YET_RECRUITING
Durban
Aliwal Shoal Medical and Clinical Trials Center
NOT_YET_RECRUITING
Emkhomazi
Eden Heart Research Centre
NOT_YET_RECRUITING
Mossel Bay
Ryexo Clinical Research -Wilgers
NOT_YET_RECRUITING
Pretoria
FCRN Clinical Trial Centre
NOT_YET_RECRUITING
Vereeniging
MeDiNova Merc Clinical Research
NOT_YET_RECRUITING
Welkom
Spain
Vithas Xanit International Hospital - Gastroenterology
NOT_YET_RECRUITING
Benalmádena
Hospital San Pedro de Alcántara
NOT_YET_RECRUITING
Cáceres
C.A.P. Canet de Mar
NOT_YET_RECRUITING
Canet De Mar
Hospital Universitario Virgen de las Nieves
NOT_YET_RECRUITING
Granada
Hospital De Jerez De La Frontera
RECRUITING
Jerez De La Frontera
Hospital Universitario de Bellvitge - Neumología
NOT_YET_RECRUITING
L'hospitalet De Llobregat
Fundacion Jimenez Diaz
NOT_YET_RECRUITING
Madrid
Hospital Universitario La Paz - Neumologia
NOT_YET_RECRUITING
Madrid
Hospital Universitario Virgen de la Victoria
RECRUITING
Málaga
Hospital Quirónsalud Marbella
NOT_YET_RECRUITING
Marbella
Hospital Universitario Son Espases
NOT_YET_RECRUITING
Palma De Mallorca
Clinica Universidad de Navarra - Neumología
RECRUITING
Pamplona
Complejo Hospitalario de Navarra
NOT_YET_RECRUITING
Pamplona
Hospital Universitario Quironsalud Madrid
NOT_YET_RECRUITING
Pozuelo De Alarcón
Hospital Universitario Virgen del Rocio
NOT_YET_RECRUITING
Seville
Hospital Sierrallana - Neumologia
NOT_YET_RECRUITING
Torrelavega
Hospital Clinico Universitario De Valencia - Neumologia
NOT_YET_RECRUITING
Valencia
Taiwan
National Taiwan University Hospital - Yunlin Branch - Douliou
NOT_YET_RECRUITING
Douliu
KMU Chung-Ho Memorial Hospital
NOT_YET_RECRUITING
Kaohsiung City
National Taiwan University Hospital - Yunlin Branch - Douliou
NOT_YET_RECRUITING
Kaohsiung City
Kuang Tien General Hospital - XiangShang
NOT_YET_RECRUITING
Taichung
Taichung Veterans General Hospital - Chest Medicine
NOT_YET_RECRUITING
Taichung
Chi Mei Medical Center - YongKang - Pulmonary Medicine
NOT_YET_RECRUITING
Tainan City
Taipei Medical University - Taipei Medical University Hospital - Internal Medicine
NOT_YET_RECRUITING
Taipei
Chang Gung Medical Foundation - LinKou Chang Gung Memorial Hospital - Pulmonary
NOT_YET_RECRUITING
Taoyuan District
Thailand
Thammasat University Hospital - Pulmonary and Pulmonary Critic
NOT_YET_RECRUITING
Khlong Luang
Khon Kaen University, Srinagarind Hospital
NOT_YET_RECRUITING
Khon Kaen
Turkey
T.C. Saglik Bakanligi - Izmir Sehir Hastanesi
NOT_YET_RECRUITING
Alsancak
Hacettepe Universitesi Hastaneleri
NOT_YET_RECRUITING
Altındağ
T.C. Saglik Bakanligi - Ankara Etlik sehir Hastanesi
NOT_YET_RECRUITING
Altındağ
Uludag Universitesi (Uludag University)
NOT_YET_RECRUITING
Beşevler
Istanbul Uni Istanbul Tip Fakultesi
NOT_YET_RECRUITING
Fatih
Medical Park Kocaeli Hastanesi
NOT_YET_RECRUITING
Köseköy
Inonu Uni. Turgut Ozal Tip Merkezi
NOT_YET_RECRUITING
Malatya
Marmara University Pendik EAH
NOT_YET_RECRUITING
Pendik
Ozel Medical Park Samsun Hastanesi
NOT_YET_RECRUITING
Samsun
Karadeniz Teknik Uni Farabi Hastane
NOT_YET_RECRUITING
Trabzon
T.C. Saglik Bakanligi-S.B.U. Bursa Yuksek Ihtisas Egitim ve Arastirma Hastanesi
NOT_YET_RECRUITING
Yıldırım
Ukraine
KNP Cherkaska oblasna likarnia
NOT_YET_RECRUITING
Cherkasy
KNPTs inf.zakhv.Iv-Frank.obl.rady
NOT_YET_RECRUITING
Ivano-frankivsk
DU NNTs im. Yanovskoho
NOT_YET_RECRUITING
Kyiv
Klin.likarnia na zal.transporti №2
NOT_YET_RECRUITING
Kyiv
MTs Universalna klinika Oberih
NOT_YET_RECRUITING
Kyiv
MTs Klinika Hospodarskykh
NOT_YET_RECRUITING
Ternopil
Uzh.miska bahatoprofilna klin.lik.
NOT_YET_RECRUITING
Úzhgorod
Lik.z nevidkl. staniv ta ekstr.dop.
NOT_YET_RECRUITING
Uzhhorod
Medychnyi tsentr Puls
NOT_YET_RECRUITING
Vinnytsia
KNP Likarnia №1 Zhytom.misk.rady
NOT_YET_RECRUITING
Zhytomyr
United Kingdom
Royal Primary Care - Ashgate
NOT_YET_RECRUITING
Chesterfield
Lakeside Healthcare
NOT_YET_RECRUITING
Corby
NHS Tayside - Ninewells Hospital
NOT_YET_RECRUITING
Dundee
Synexus Midlands Clinical Research Centre
RECRUITING
Edgbaston
Panthera Biopartners - North London
RECRUITING
Enfield
Futuremeds - Glasgow
NOT_YET_RECRUITING
Glasgow
NHS Greater Glasgow & Clyde - Gartnavel General Hospital - Respiratory
NOT_YET_RECRUITING
Glasgow
Panthera Biopartners - Glasgow
RECRUITING
Glasgow
Velocity Clinical Research - High Wycombe
RECRUITING
High Wycombe
Leeds Teaching Hospitals NHS Trust - St James' University Hospital
NOT_YET_RECRUITING
Leeds
Medicines Evaluation Unit
NOT_YET_RECRUITING
Manchester
Futuremeds -Teesside
RECRUITING
Metropolitan Borough Of Wirral
FutureMeds Wirral
RECRUITING
Metropolitan Borough Of Wirral
Bioluminux Clinical Research
RECRUITING
Milton Keynes
FutureMeds - Newcastle
RECRUITING
Newcastle
Ashburton Surgery
NOT_YET_RECRUITING
Newton Abbot
Panthera Biopartners - Preston
NOT_YET_RECRUITING
Preston
Royal Berkshire Hospital
NOT_YET_RECRUITING
Reading
Panthera Biopartners - Manchester
RECRUITING
Rochdale
Velocity Romford
RECRUITING
Romford
Panthera Biopartners Sheffield 3 Skye Edge Avenue
RECRUITING
Sheffield
Panthera Biopartners - York
RECRUITING
York
Viet Nam
Nhan Dan Gia Dinh Hospital
NOT_YET_RECRUITING
Ho Chi Minh City
University Medical Center of Ho Chi Minh City
NOT_YET_RECRUITING
Ho Chi Minh City
Contact Information
Primary
Upstream Bio Clinical Trials Information (Privacy Notice: https://upstreambio.com/privacy-policy/)
clinicaltrials@upstreambio.com
888-446-3130
Time Frame
Start Date: 2025-07-02
Estimated Completion Date: 2028-07
Participants
Target number of participants: 666
Treatments
Experimental: Verekitug (UPB-101) 100 mg and Placebo
Participants will receive 0.5 milliliter (mL) of the formulated solution (containing 100 milligrams \[mg\] of verekitug \[UPB-101\]) and 2.0 mL of matching placebo subcutaneously in two separate injections every 12 weeks up to Week 96.
Experimental: Verekitug (UPB-101) 400 mg and Placebo
Participants will receive 2.0 mL of the formulated solution (containing 400 mg of verekitug \[UPB-101\]) and 0.5 mL of matching placebo subcutaneously in two separate injections every 24 weeks up to Week 96. Participants will also receive 2.0 mL and 0.5 mL of matching placebo subcutaneously in two separate injections at Weeks 12, 36, 60 and 84 visits.
Placebo_comparator: Placebo
Participants will receive 0.5 mL of matching placebo and 2.0 mL of matching placebo subcutaneously in two separate injections every 12 weeks up to Week 96.
Related Therapeutic Areas
Sponsors
Leads: Upstream Bio Inc.