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Last Updated: 10/19/2022

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  • Majority of doctors fall within this rating.
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Last Updated: 10/19/2022

Colorectal cancer (CRC), also known as colon cancer, is a cancer that occurs in the large intestine (colon) or rectum and is the third most diagnosed cancer in the U.S., appearing more frequently in older men and women over the age of 50. Colorectal cancer often begins with appearance of small, non-cancerous (benign) growths (polyps) in the lining of the colon that are without symptoms. Some of these polyps can eventually develop into tumors and become colorectal cancer. Not all polyps become cancerous. The risk of polyps developing into cancer depends on the type of polyps, of which there are two main types:   1) Adenomas are considered pre-cancerous because they sometimes become adenocarcinomas, which represent 96% of colorectal cancers. 2) Hyperplastic and inflammatory polyps occur more often and are usually non-cancerous. Additional risks for polyps becoming cancerous include their size, number, or whether they have abnormal cells. If a polyp does become cancerous, the cancer can spread into the lining of the colon or rectum, and eventually through other layers. Once inside the wall of the colon or rectum, the cancer can then spread into the blood vessels and lymph system (nodes) or other, distant parts of the body (metastasis).  A few other, less common colorectal cancers include: Carcinoid Tumors that arise from hormone-producing cells in the colon. Gastrointestinal Stromal Tumors (GISTs) that arise from special cells in the lining of the colon, and which can be either cancerous or non-cancerous (benign); however, GISTs do not commonly appear in the colon. Lymphomas, which are cancers that begin in lymph nodes. Sarcomas, which begin in the blood vessels, muscles, or connective tissues, and rarely appear as colorectal cancers. Colorectal cancer is classified based on the following stages: Stage 0 – Carcinoma in Situ: abnormal cells may be found in the lining (mucosa) of the colon or rectum. Stage I – Cancer has formed in the lining (mucosa) of the colon or rectal wall and has spread to the submucosa (outer layer) or the muscle layer. Stage II (IIA, IIB, IIC) – Cancer has spread through the muscle of the colon or rectum to the outer layer (serosa); Cancer has spread through the outer layer (serosa) to the lining of the abdomen (peritoneum); Cancer has spread through the outer layer (serosa) to other organs. Stage III (IIA, IIIB, IIIC) – Cancer has spread through the mucosa (inner layer), submucosa (outer layer), or muscle layer of colon or rectum, or through the colon or rectal wall to four-to-six lymph nodes; Cancer has spread through the mucosa (inner layer), submucosa (outer layer), or muscle layer of colon or rectum, or through the colon or rectal wall to the mucosa that lines the abdomen (peritoneum) and one-to-three lymph nodes, or four-to six lymph nodes, or seven or more lymph nodes; Cancer has spread to the mucosa lining the abdomen (peritoneum) and four-to six lymph nodes, or seven or more lymph nodes, or to nearby organs. Stage IV (IVA, IVB, IVC) – Cancer has spread to one area or organ not near the colon or rectum, such as liver, lung, ovary, or distant lymph node; Cancer has spread to more than one area or organ, such as liver, lung, ovary, or distant lymph node; Cancer has spread to the lining of the wall of the abdomen (peritoneum) and may have spread to other organs. The level of staging for colorectal cancer determines its treatment and outcomes (prognosis).

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MediFind is the industry authority on identifying the leading medical experts and latest research in order to help patients facing complex health challenges, including , make better health decisions. Leveraging our expertise in natural language processing and machine learning across thousands of diseases, we uncover physicians who are leading authorities on . MediFind identifies these experts using proprietary world-class models that assess over 2.5 million global doctors based on a range of variables, including research leadership, patient volume, peer standing, and connectedness to other experts. Learn more about our methodology by exploring how MediFind works.