The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma: A Retrospective Study
This study aimed to reduce radiation-induced thyroid injury without compromising control of the cervical region by optimizing the delineation of the cervical lymph node drainage area.
• The pathological diagnosis was newly diagnosed non-keratinizing squamous cell carcinoma nasopharyngeal carcinoma.
• The clinical stage is T1-4N0-3M0 (stage I\
‣ IVa, UICC/AJCC 8th edition);
• There is no history of hypothyroidism or hyperthyroidism before treatment;
• Using intensity-modulated radiotherapy technology,
• Complete radical dose radiotherapy;
• KPS≥70 points;
• Age 18-70 years old;
• Male or female who is not pregnant or lactating;
• Hematological examination: white blood cells \> 4×109/L, neutrophils \> 2×109/L, hemoglobin \> 90g/L, platelets \> 100×109/L;
⁃ Liver function: ALT, AST \< 1.5×ULN, ALP \< 2.5×ULN, bilirubin \< ULN.
⁃ Renal function: creatinine \> 60 ml/min;
⁃ The patient signs the informed consent form;