The Effect of Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to evaluate the effect of the treatment with levothyroxine on cardiac function in children with subclinical hypothyroidism.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 15
Healthy Volunteers: f
View:
• Age from 4 to 15 years.
• Both sexes.
• Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU/L with normal free T4 and ft3 in different measurement 4 - 6 weeks apart.
Locations
Other Locations
Egypt
Tanta University
RECRUITING
Tanta
Contact Information
Primary
Zeinab E Elshareef, MBBCH
zeinabibraheem26@gmail.com
00201001700194
Time Frame
Start Date: 2025-05-24
Estimated Completion Date: 2026-05-01
Participants
Target number of participants: 40
Treatments
Experimental: Treatment group
Children with subclinical hypothyroidism who will receive L-thyroxine treatment in a dose of 2μg/kg/d (the smallest dose can be given) and the dose will be titrated every 4 weeks until a normal thyroid-stimulating hormone (TSH) level is maintained.
No_intervention: No treatment group
Children with subclinical hypothyroidism who will receive no treatment.
Related Therapeutic Areas
Sponsors
Leads: Tanta University