Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

Journal: Indian Pediatrics
Treatment Used: Early Initiation of Steroid-sparing Drugs
Number of Patients: 0
Published:
MediFind Summary

Summary: This study reported on hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis (bleeding in lungs of unknown cause).

Conclusion: Early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects in children with idiopathic pulmonary hemosiderosis (bleeding in lungs of unknown cause).

Abstract

Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.

Authors
Priyankar Pal, Hriday De, Prabhas Giri, Nupur Ganguly, Alolika Mandal

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