Learn About Immune Thrombocytopenia

What is the definition of Immune Thrombocytopenia?

Immune thrombocytopenia is a disorder characterized by a blood abnormality called thrombocytopenia, which is a shortage of blood cells called platelets that are needed for normal blood clotting.

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What are the causes of Immune Thrombocytopenia?

The genetic cause of immune thrombocytopenia is unclear. This condition occurs when the body's own immune system malfunctions and attacks the body's tissues and organs (autoimmunity). Normally, the immune system produces proteins called antibodies, which attach to specific foreign particles and germs, marking them for destruction. In immune thrombocytopenia, the immune system abnormally destroys platelets and makes fewer platelets than normal. People with immune thrombocytopenia produce antibodies that attack normal platelets. The platelets are destroyed and eliminated from the body, resulting in a shortage of these cells in affected individuals. Some of these antibodies also affect the cells in the bone marrow that produce platelets (known as megakaryocytes), which leads to a decrease in platelet production, further reducing the number of platelets in the blood.

How prevalent is Immune Thrombocytopenia?

The incidence of immune thrombocytopenia is approximately 4 per 100,000 children and 3 per 100,000 adults. In adults with immune thrombocytopenia, women are affected more often than men.

Is Immune Thrombocytopenia an inherited disorder?

Immune thrombocytopenia and other autoimmune disorders can run in families, but the inheritance pattern is usually unknown. People with a first-degree relative (such as a parent or sibling) with immune thrombocytopenia likely have an increased risk of developing the disorder themselves.

Who are the top Immune Thrombocytopenia Local Doctors?
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Highly rated in
9
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Pediatrics
Pediatric Hematology Oncology

NewYork-Presbyterian Komansky Children's Hospital

525 E 68th St 
New York, NY 

James Bussel is a Pediatrics specialist and a Pediatric Hematologist Oncology expert in New York, New York. Bussel has been practicing medicine for over 47 years and is rated as an Elite expert by MediFind in the treatment of Immune Thrombocytopenia. He is also highly rated in 9 other conditions, according to our data. His top areas of expertise are Immune Thrombocytopenia, Blood Clots, Hemophagocytic Lymphohistiocytosis, and Leukemia. He is licensed to treat patients in New York.

Elite
Highly rated in
5
conditions

Qilu Hospital Of Shandong University

Jinan, CN 

Ming Hou practices in Jinan, China. Hou is rated as an Elite expert by MediFind in the treatment of Immune Thrombocytopenia. They are also highly rated in 5 other conditions, according to our data. Their top areas of expertise are Immune Thrombocytopenia, Purpura, Thrombocytopenia, and Blood Clots.

 
 
 
 
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Elite
Highly rated in
4
conditions

Imperial College London

London, ENG, GB 

Nichola Cooper practices in London, United Kingdom. Cooper is rated as an Elite expert by MediFind in the treatment of Immune Thrombocytopenia. She is also highly rated in 4 other conditions, according to our data. Her top areas of expertise are Immune Thrombocytopenia, Purpura, Thrombocytopenia, and Blood Clots.

What are the latest Immune Thrombocytopenia Clinical Trials?
ITALIAN ADULT IMMUNE THROMBOCYTOPENIA (ITP) REGISTRY Investigation on a Dynamic Cohort of Italian Patients With Active ITP
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An Open-label Study to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic Immune Thrombocytopenia
Who are the sources who wrote this article ?

Published Date: June 01, 2017Published By: National Institutes of Health

What are the Latest Advances for Immune Thrombocytopenia?
Efficacy and Safety of Avatrombopag in Patients with Chronic Immune Thrombocytopenia: A Systematic Literature Review and Network Meta-Analysis.
An Imperfect Marker: SLE and TTP-Like MAHA Without Low ADAMTS13.
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Diagnosis and management of severe neonatal thrombocytopenia due to maternal alloimmunization against fetal platelet antigens: case study and literature review.