Effect of Closed Tracheal Aspiration Associated With Expiratory Pause in Pediatrics: A Randomized, Crossover Clinical Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Introduction: Patients on mechanical ventilation suffer alterations in the viscoelastic characteristics of the mucus due to changes in the humidity and temperature of the inhaled air and in the respiratory volumes and flows. The literature has pointed out the use of mechanical ventilators as a tool for mobilizing secretions and closed-system aspiration associated with expiratory pause has been shown to be effective in mobilizing secretions.

Objectives: To assess whether there is a difference in the mass of aspirated secretion with the application of the expiratory pause during aspiration.

Methods: A crossover, randomized study. Applied to children aged 0 to 5 years and 11 months who are intubated for 24 hours with orotracheal tubes or tracheostomy. There will be an exclusion of patients who present with undrained pneumothorax, cranial hypertension or any other clinical situation that has a clinical contraindication to aspiration and patients whose parents do not agree to participate in the study. The technique will be during aspiration in the tube with where to apply or not the expiratory pause on the mechanical ventilator. This secretion will be weighed so that there is fidelity in the results.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 5
Healthy Volunteers: No
View:

• Patients aged 0 to 5 years and 11 months who have been on invasive mechanical ventilation for more than 24 hours through an orotracheal cannula or tracheostomy will be included in the study.

Locations
Other Locations
Brazil
Albert Eisntein Hospital
Recruiting
São Paulo
Time Frame
Start Date: April 22, 2022
Estimated Completion Date: December 2023
Participants
Target number of participants: 40
Treatments
Active Comparator: with pause- without pause
Start with an expiratory pause during aspiration and after 6hours the aspiration is performed without an expiratory pause
Active Comparator: without pause - with pause
Start without an expiratory pause during aspiration and after 6hours the aspiration is performed with an expiratory pause
Related Therapeutic Areas
Sponsors
Leads: Hospital Israelita Albert Einstein

This content was sourced from clinicaltrials.gov