Learn About Intestinal Pseudo-Obstruction

What is the definition of Intestinal Pseudo-Obstruction?

Intestinal pseudo-obstruction is a condition in which there are symptoms of blockage of the intestine (bowels) without any physical blockage.

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What are the alternative names for Intestinal Pseudo-Obstruction?

Primary intestinal pseudo-obstruction; Acute colonic ileus; Colonic pseudo-obstruction; Idiopathic intestinal pseudo-obstruction; Ogilvie syndrome; Chronic intestinal pseudo-obstruction; Paralytic ileus - pseudo-obstruction

What are the causes of Intestinal Pseudo-Obstruction?

In intestinal pseudo-obstruction, the intestine is unable to contract and push food, stool, and air through the digestive tract. The disorder most often affects the small intestine, but can also occur in the large intestine.

The condition may start suddenly or be a chronic or long-term problem. It is most common in children and older people. The cause of the problem is often unknown.

Risk factors include:

  • Cerebral palsy or other brain or nervous system disorders.
  • Chronic kidney, lung, or heart disease.
  • Staying in bed for long periods of time (bedridden).
  • Taking drugs that slow intestinal movements. These include narcotic (pain) medicines and drugs used when you are not able to keep urine from leaking out.
What are the symptoms of Intestinal Pseudo-Obstruction?

Symptoms include:

  • Abdominal pain
  • Bloating
  • Constipation
  • Nausea and vomiting
  • Swollen abdomen (abdominal distention)
  • Weight loss
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What are the current treatments for Intestinal Pseudo-Obstruction?

The following treatments may be tried:

  • Colonoscopy may be used to remove air from the large intestine.
  • Fluids can be given through a vein to replace fluids lost from vomiting or diarrhea.
  • Nasogastric suction involving a nasogastric (NG) tube placed through the nose into the stomach can be used to remove air from the bowel.
  • Neostigmine may be used to treat intestinal pseudo-obstruction that is only in the large bowel (Ogilvie syndrome).
  • Special diets often do not work. However, vitamin B12 and other vitamin supplements should be used for people with vitamin deficiency.
  • Stopping the medicines that may have caused the problem (such as narcotic drugs) may help.

In severe cases, surgery may be needed.

Who are the top Intestinal Pseudo-Obstruction Local Doctors?
Elite
Highly rated in
8
conditions

University Of Manchester

Manchester, ENG, GB 

Dipesh Vasant is in Manchester, United Kingdom. Vasant is rated as an Elite expert by MediFind in the treatment of Intestinal Pseudo-Obstruction. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Intestinal Pseudo-Obstruction, Irritable Bowel Syndrome, Colitis, and Swallowing Difficulty.

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Highly rated in
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University Of Bologna

Department Of Medical And Surgical Sciences, Centre For Chronic Intestinal Failure Clinical Nutrition And Metabolism Unit 
Bologna, IT 

Loris Pironi is in Bologna, Italy. Pironi is rated as an Elite expert by MediFind in the treatment of Intestinal Pseudo-Obstruction. They are also highly rated in 11 other conditions, according to our data. Their top areas of expertise are Intestinal Pseudo-Obstruction, Short Bowel Syndrome, Radiation Enteritis, and MELAS Syndrome.

 
 
 
 
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Elite
Highly rated in
17
conditions

University Of Ferrara

Department Of Translational Medicine 
Ferrara, IT 44121

Roberto De Giorgio is in Ferrara, Italy. De Giorgio is rated as an Elite expert by MediFind in the treatment of Intestinal Pseudo-Obstruction. He is also highly rated in 17 other conditions, according to our data. His top areas of expertise are Intestinal Pseudo-Obstruction, Short Bowel Syndrome, Mitochondrial Neurogastrointestinal Encephalopathy Disease, and MELAS Syndrome.

What is the outlook (prognosis) for Intestinal Pseudo-Obstruction?

Most cases of acute pseudo-obstruction get better in a few days with treatment. In chronic forms of the disease, symptoms can come back and get worse over many years.

What are the possible complications of Intestinal Pseudo-Obstruction?

Complications may include:

  • Diarrhea
  • Rupture (perforation) of the intestine
  • Vitamin deficiencies
  • Weight loss
When should I contact a medical professional for Intestinal Pseudo-Obstruction?

Call your provider if you have abdominal pain that does not go away or other symptoms of this disorder.

Digestive system organs
What are the latest Intestinal Pseudo-Obstruction Clinical Trials?
Improved Quality of Life in Children With Intestinal Failure - a Randomised Intervention Trial
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Congenital Muscle Disease Patient and Proxy Reported Outcome Study
What are the Latest Advances for Intestinal Pseudo-Obstruction?
Preliminary experience with double-tract reconstruction combined with π-shaped esophagojejunal anastomosis after total laparoscopic proximal gastrectomy for the treatment of adenocarcinoma of esophagogastric junction.
Fecal microbiota transplantation in the treatment of acute intestinal pseudo obstruction secondary to intracerebral hemorrhage: a case report and literature review.
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Clinical Observation of Treatment Efficacy in Critical Paralytic Ileus Disease with Integrated Traditional Chinese and Western Medicine: A Randomized Controlled Trial.
Who are the sources who wrote this article ?

Published Date : April 30, 2020
Published By : Bradley J. Winston, MD, board certified in gastroenterology and hepatology, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Camilleri M. Disorders of gastrointestinal motility. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 127.

Rayner CK, Hughes PA. Small intestinal motor and sensory function and dysfunction. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 99.