Clinical Trials

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Clinical Trial
  • Status: Recruiting
  • Phase: N/A
  • Intervention Type: Device
  • Participants: 500
  • Start Date: May 6, 2019
New Non-invasive Modalities for Assessing Retinal Structure and Function:Preliminary Investigation
Clinical Trial
  • Status: Recruiting
  • Phase: Phase 2/Phase 3
  • Intervention Type: Drug
  • Participants: 14
  • Start Date: March 26, 2019
Study of Efficacy of Befizal® 200 mg for the Treatment of Leber Hereditary Optic Neuropathy
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Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 3
  • Intervention Type: Drug, Genetic
  • Participants: 90
  • Start Date: March 12, 2018
Efficacy and Safety of Bilateral Intravitreal Injection of GS010: A Randomized, Double-Masked, Placebo-Controlled Trial in Subjects Affected With G11778A ND4 Leber Hereditary Optic Neuropathy for Up to One Year
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 3
  • Intervention Type: Genetic, Other
  • Participants: 61
  • Start Date: January 9, 2018
Long-term Follow-up of ND4 LHON Subjects Treated With GS010 Ocular Gene Therapy in the RESCUE or REVERSE Phase III Clinical Trials
Clinical Trial
  • Status: Active, not recruiting
  • Phase: N/A
  • Intervention Type: Drug
  • Participants: 120
  • Start Date: January 8, 2018
Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 2/Phase 3
  • Intervention Type: Drug
  • Participants: 159
  • Start Date: December 27, 2017
A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy
Clinical Trial
  • Status: Active, not recruiting
  • Intervention Type: Drug
  • Participants: 250
  • Start Date: September 2016
A Non-interventional Study of Clinical Experience in Patients Prescribed Raxone® for the Treatment of Leber's Hereditary Optic Neuropathy (LHON)
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 4
  • Intervention Type: Drug
  • Participants: 250
  • Start Date: May 2016
External Natural History Controlled, Open-Label Intervention Study to Assess the Efficacy and Safety of Long-Term Treatment With Raxone® in Leber's Hereditary Optic Neuropathy (LHON)
Clinical Trial
  • Status: Recruiting
  • Phase: N/A
  • Intervention Type: Procedure
  • Participants: 500
  • Start Date: January 2016
Bone Marrow Derived Stem Cell Ophthalmology Treatment Study II
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 1
  • Intervention Type: Drug
  • Participants: 30
  • Start Date: July 14, 2014
An Open-label Dose Escalation Study of an Adeno-associated Virus Vector (scAAV2-P1ND4v2) for Gene Therapy of Leber's Hereditary Optic Neuropathy (LHON) Caused by the G11778A Mutation in Mitochondrial DNA
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