Learn About Leukemia

What is the definition of Leukemia?

Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are produced.

The term leukemia means white blood. White blood cells (leukocytes) are used by the body to fight infections and other foreign substances. Leukocytes are made in the bone marrow.

Leukemia leads to an uncontrolled increase in the number of white blood cells.

The cancerous cells prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made. Life-threatening symptoms can then develop as normal blood cells decline.

The cancer cells can spread to the bloodstream and lymph nodes. They can also travel to the brain and spinal cord (the central nervous system) and other parts of the body.

Leukemia can affect children and adults.

Leukemias are divided into two major types:

  • Acute (which progresses quickly)
  • Chronic (which progresses more slowly)

The main types of leukemia are:

  • Acute lymphocytic leukemia (ALL)
  • Acute myelogenous leukemia (AML)
  • Chronic lymphocytic leukemia (CLL)
  • Chronic myelogenous leukemia (CML)
Bone marrow aspiration
Acute lymphocytic leukemia - photomicrograph
Auer rods
Chronic lymphocytic leukemia - microscopic view
Chronic myelocytic leukemia - microscopic view
Chronic myelocytic leukemia
Chronic myelocytic leukemia
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Who are the top Leukemia Local Doctors?
Elite
Highly rated in
30
conditions
Oncology
Hematology Oncology
Hematology

University of Texas System

Physicians Referral Service

1515 Holcombe Blvd 
Houston, TX 77030

Tapan Kadia is an Oncologist and a Hematologist Oncology doctor in Houston, Texas. Dr. Kadia has been practicing medicine for over 21 years and is rated as an Elite doctor by MediFind in the treatment of Leukemia. He is also highly rated in 30 other conditions, according to our data. His top areas of expertise are Acute Myeloid Leukemia, Myelodysplastic Syndrome, Leukemia, and Acute Myeloblastic Leukemia without Maturation. He is board certified in Internal Medicine, Hematology, and Medical Oncology and licensed to treat patients in Texas. Dr. Kadia is currently accepting new patients.

Elite
Highly rated in
12
conditions
Hematology Oncology
Oncology

University of California San Diego Health System

Moores Cancer Center

3855 Health Sciences Dr 
La Jolla, CA 92093

Thomas Kipps is a Hematologist Oncology specialist and an Oncologist in La Jolla, California. Dr. Kipps has been practicing medicine for over 43 years and is rated as an Elite doctor by MediFind in the treatment of Leukemia. He is also highly rated in 12 other conditions, according to our data. His top areas of expertise are Chronic B-Cell Leukemia, Chronic Lymphocytic Leukemia, Leukemia, and Richter Syndrome. He is board certified in Hematology/oncology, Internal Medicine, and Medical Oncology and licensed to treat patients in California. Dr. Kipps is currently accepting new patients.

 
 
 
 
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Learn more
Elite
Highly rated in
28
conditions
Hematology Oncology
Hematology
Oncology

Moffitt Cancer Center

Moffitt Cancer Center

12902 Usf Magnolia Drive 
Tampa, FL 33612

Jeffrey Lancet is a Hematologist Oncology specialist and a Hematologist in Tampa, Florida. Dr. Lancet has been practicing medicine for over 30 years and is rated as an Elite doctor by MediFind in the treatment of Leukemia. He is also highly rated in 28 other conditions, according to our data. His top areas of expertise are Acute Myeloid Leukemia, Myelodysplastic Syndrome, Leukemia, and Acute Myeloblastic Leukemia with Maturation. He is board certified in Hematology/oncology and licensed to treat patients in Florida. Dr. Lancet is currently accepting new patients.

What are the latest Leukemia Clinical Trials?
A Phase II, Open-label, Single Arm Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Twice Daily Midostaurin (PKC412) Combined With Standard Chemotherapy and as a Single Agent Post-consolidation Therapy in Children With Untreated FLT3-mutated AML
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An Open-Label Phase Ib/II Multi-Arm Study of OX40 Agonist Monoclonal Antibody (mAb), Anti-PDL1 mAb, Smoothened Inhibitor, Anti-CD33 mAb, Bcl-2 Inhibitor and Azacitidine as Single-Agents and/or Combinations for the Treatment of Patients With Acute Myeloid Leukemia (AML)
What are the Latest Advances for Leukemia?
The efficacy of alemtuzumab for pure red cell aplasia associated with autoimmune polyendocrine syndrome type 1.
The golden spice curcumin in cancer: A perspective on finalized clinical trials during the last 10 years.
Tired of the same old research?
Check Latest Advances
Molecular characterization of hepatitis B virus (HBV) isolated from a pediatric case of acute lymphoid leukemia, with a delayed response to antiviral treatment: a case report.
Who are the sources who wrote this article ?

Published Date : February 06, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Appelbaum FR. Acute leukemias in adults. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 95.

Hunger SP, Teachey DT, Grupp S, Aplenc R. Childhood leukemia. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 93.