Learn About Loiasis

What is the definition of Loiasis?
Loiasis is a form of filariasis (see this term), caused by the parasitic worm Loa loa, endemic to the forest and savannah regions of Central and Western Africa. Loiasis may either be asymptomatic or manifest as a large, transient area of localized, non-erythematous subcutaneous edema (Calabar swellings), adult worm migration through the sub-conjunctiva (''African eye worm'') and pruritus. Generalized itching, hives, muscle pains, arthralgias, fatigue, and adult worms visibly migrating under the surface of the skin may be observed. Severe complications such as encephalopathy have been reported in highly infected individuals receiving ivermectin during mass drug administration programs for the control of onchocerciasis and lymphatic filariasis (see these terms).
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What are the alternative names for Loiasis?
  • Loiasis
  • Mansonelliasis
  • African eye worm
  • Loa loa filariasis
  • Mansonella perstans infections
  • Mansonellosis
Who are the top Loiasis Local Doctors?
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What are the latest Loiasis Clinical Trials?
Randomized Clinical Trial, Double-blind, Single-dose Drug and Escalating Infection Intensities, Evaluating the Safety and Efficacy of Moxidectin 2 mg, Ivermectin-controlled, in Loa Loa Microfilaremic Patients
Summary: This study aims at evaluating the safety and efficacy of Moxidectin 2 mg in patients with low intensities of microfilariae of Loa loa.
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Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa
Summary: This study aims at evaluating the diagnosis performances of the LTS-2 DEC patch for onchocerciasis compared to the gold standard which are the skin snips. This study will be conducted in Cameroon in two different areas : Ngog-Mapubi and Bafia Health Districts (one area only endemic for onchocerciasis, and one area endemic for both loiasis and onchocerciasis).
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Loiasis?
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Summary: MBGapp: A Shiny application for teaching model-based geostatistics to population health scientists.
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update.
Summary: Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update.
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Loiasis (African eye worm): about a case.
Summary: Loiasis (African eye worm): about a case.