Summary: Background:~- The rare disease melorheostosis causes bones to thicken. This may lead to pain, and can affect bones, joints, and muscles. Researchers want to learn more about the disease and how it progresses.~Objective:~-To see what happens to people with melorheostosis over time and understand the causes of the disease.~Eligibility:~People 18 and over with melorheostosis.~Their unaffected relativ...