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Last Updated: 11/29/2022

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A Phase II Study of Topical Sodium Nitrite in Patients With Sickle Cell and Leg Ulcers

Summary: The investigators propose a Phase II study, prospective and placebo controlled, of a topical cream containing sodium nitrite compared to the current standard of care. Sodium nitrite is a local donor of nitric oxide, which is known to improve blood flow and decrease bacterial load in the ulcer bed. The primary objectives are to evaluate the safety of topical sodium nitrite cream treatment in patien...

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Last Updated: 11/29/2022