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Dr. Jan Am Smeitink

Radboud University Medical Center


Jan Smeitink is in Nijmegen, Netherlands. Dr. Smeitink is a global expert in Mitochondrial Complex 1 Deficiency. They have been an author on 217 peer reviewed articles in the past 15 years. In particular, they have been an author on 24 peer reviewed articles regarding Mitochondrial Complex 1 Deficiency.


Nijmegen, GE 6500H, NL

Latest Advances

  • Condition: Mitochondrial m.3243A>G Spectrum Disorders
  • Journal: Clinical pharmacology and therapeutics
  • Treatment Used: KH176
  • Number of Patients: 18
  • Published —
This study evaluated the tolerability, safety, pharmacokinetics, pharmacodynamics, and effectiveness of twice daily oral 100 mg KH176 in adult mitochondrial m.3243A>G Spectrum Disorders patients without cardiovascular involvement.

Clinical Trials


Nijmegen, GE 6500H, NL


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