Learn About Pigment-Dispersion Syndrome

What is the definition of Pigment-Dispersion Syndrome?
Pigment-dispersion syndrome is an eye disorder that occurs when pigment granules that normally adhere to the back of the iris (the colored part of the eye) flake off into the clear fluid produced by the eye (aqueous humor). These pigment granules may flow towards the drainage canals of the eye, slowly clogging them and raising the pressure within the eye (intraocular pressure or IOP). This rise in eye pressure can cause damage to the optic nerve (the nerve in the back of the eye that carries visual images to the brain). If the optic nerve becomes damaged, Pigment-dispersion syndrome becomes pigmentary glaucoma. This happens in about 30% of cases. While men and women are affected in equal numbers, men develop pigmentary glaucoma up to 3 times more often than women. Myopia (nearsightedness) appears to be an important risk factor in the development of Pigment-dispersion syndrome and is present in up to 80% of affected individuals. The condition may be sporadic or follow an autosomal dominant pattern of inheritance with reduced penetrance . At least one gene locus on chromosome 7 has been identified.
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What are the alternative names for Pigment-Dispersion Syndrome?
  • Pigment-dispersion syndrome
Who are the top Pigment-Dispersion Syndrome Local Doctors?
JS
Dr. Joel S. Schuman
Ophthalmology | General Surgery
Elite
Highly rated in
6
conditions
Ophthalmology
General Surgery

NYU Langone Health

NYU Ophthalmology Associates

222 E 41st St 
New York, NY 10017

Joel Schuman is an Ophthalmologist and a General Surgeon in New York, New York. Dr. Schuman has been practicing medicine for over 38 years and is rated as an Elite doctor by MediFind in the treatment of Pigment-Dispersion Syndrome. He is also highly rated in 6 other conditions, according to our data. His top areas of expertise are Glaucoma, Pigment-Dispersion Syndrome, Optic Glioma, and Amaurosis Fugax. He is licensed to treat patients in Pennsylvania. Dr. Schuman is currently accepting new patients.

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LP
Dr. Louis R. Pasquale
Ophthalmology
Elite
Highly rated in
8
conditions
Ophthalmology

Mount Sinai Health System

Mount Sinai Medical Center

17 E 102nd St 
New York, NY 10029

Louis Pasquale is an Ophthalmologist in New York, New York. Dr. Pasquale has been practicing medicine for over 36 years and is rated as an Elite doctor by MediFind in the treatment of Pigment-Dispersion Syndrome. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Glaucoma, Pigment-Dispersion Syndrome, Fish-Eye Disease, and Age-Related Macular Degeneration ARMD. He is licensed to treat patients in New York and Massachusetts. Dr. Pasquale is currently accepting new patients.

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Dr. Janey L. Wiggs
Ophthalmology | Medical Genetics
Elite
Highly rated in
4
conditions
Ophthalmology
Medical Genetics

Mass General Brigham

Main Campus

243 Charles St 
Boston, MA 2114

Janey Wiggs is an Ophthalmologist and a Medical Genetics doctor in Boston, Massachusetts. Dr. Wiggs has been practicing medicine for over 38 years and is rated as an Elite doctor by MediFind in the treatment of Pigment-Dispersion Syndrome. She is also highly rated in 4 other conditions, according to our data. Her top areas of expertise are Pigment-Dispersion Syndrome, Glaucoma, Fish-Eye Disease, and Optic Nerve Atrophy. She is licensed to treat patients in Massachusetts. Dr. Wiggs is currently accepting new patients.

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What are the latest Pigment-Dispersion Syndrome Clinical Trials?
A Randomized ( 1:1), Double-Masked, Multi-Center, Two-Treatment, Single-Period, Parallel Design, Mutiple Dose Bioequivalence Study With Clinical End-Point of Bimatoprost Ophthalmic Solution 0.01% of Mankind Pharma Limited With LUMIGAN (Bimatoprost Ophthalmic Solution) 0.01% of Allergan, Inc., in Subjects With Chronic Open-Angle Glaucoma Or Ocular Hypertension in Both Eyes
Status: Recruiting
Start Date: October 2, 2021
Intervention Type: Drug
Study Drugs: Bimatoprost
Phase: Phase 3
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Summary: This is a randomized, double-masked, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes.~Test Product - Bimatoprost Ophthalmic Solution, 0.01% of Mankind Pharma Limited, India~Reference Product - LUMIGAN® (Bimatopr...
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Non-inferiority of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Patients With Open-angle Glaucoma or Ocular Hypertension
Status: Recruiting
Start Date: November 6, 2021
Intervention Type: Other, Device
Study Drugs: Timolol
Phase: Not Applicable
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Summary: The purpose of this study is to evaluate the effect of microdrops vs. standard eyedrops of 0.5% timolol maleate in adults with primary open-angle glaucoma or ocular hypertension in terms of intraocular pressure-lowering efficacy and cardiovascular side effects.
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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Pigment-Dispersion Syndrome?
Six-month outcomes of combined conventional needle goniotomy and phacoemulsification in eyes with early to moderate primary open-angle and pseudoexfoliation glaucoma and ocular hypertension.
Condition: Primary Open-Angle and Pseudoexfoliation Glaucoma (POAG and PXG) and Ocular Hypertension (OHTN)
Journal: Indian journal of ophthalmology
Treatment Used: Combined Phacoemulsification and Goniotomy
Number of Patients: 30
Published: June 01, 2022
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Summary: Six-month outcomes of combined conventional needle goniotomy and phacoemulsification in eyes with early to moderate primary open-angle and pseudoexfoliation glaucoma and ocular hypertension.
Clinical profile and long term outcomes of eyes with choroidal detachment following trabeculectomy.
Condition: Choroidal Detachment (CD)
Journal: Indian journal of ophthalmology
Treatment Used: Trabeculectomy
Published: May 03, 2022
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Summary: Clinical profile and long term outcomes of eyes with choroidal detachment following trabeculectomy.
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Secondary open-angle glaucoma following YAG-laser vitreolysis.
Condition: Secondary Open-Angle Glaucoma
Journal: BMJ case reports
Treatment Used: Surgery with Baerveldt Glaucoma Valve (BGV)
Number of Patients: 1
Published: April 29, 2022
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Summary: Secondary open-angle glaucoma following YAG-laser vitreolysis.
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