Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin.

Journal: Pediatric Dermatology
Treatment Used: Ustekinumab and Acitretin
Number of Patients: 1
MediFind Summary

Summary: This case report describes a 5-year-old girl with pityriasis rubra pilaris (inflammatory skin disease; PRP) treated with ustekinumab and acitretin.

Conclusion: A girl with pityriasis rubra pilaris (inflammatory skin disease) was successfully treated with ustekinumab and acitretin.


Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease that occurs with phenotypic variability in adults of all ages as well as in children. Data on the treatment of PRP is limited. Here, we report a 5-year-old girl with widespread skin involvement and prominent palmoplantar hyperkeratosis who was initially treated for psoriasis. After reevaluation, a diagnosis of PRP was made, and the patient had an excellent therapeutic response to ustekinumab and acitretin.

Medek Katharina, Selhofer Sylvia, Buchner Matthias, Mrowietz Ulrich, Laimer Martin

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