Clinical Trials

Search for trials
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 12
  • Start Date: March 2021
A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of DCR-PHXC in Patients With Primary Hyperoxaluria Type 1 or 2 and Severe Renal Impairment, With or Without Dialysis
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 21
  • Start Date: January 21, 2020
ILLUMINATE-C: A Single Arm Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1 (PH1)
Search for trials
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 36
  • Start Date: October 28, 2019
A Phase 2 Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of DCR-PHXC Solution for Injection (Subcutaneous Use) in Patients With Primary Hyperoxaluria
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 18
  • Start Date: April 22, 2019
ILLUMINATE-B: An Open-Label Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 39
  • Start Date: November 27, 2018
ILLUMINATE-A: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study With an Extended Dosing Period to Evaluate the Efficacy and Safety of Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1
Clinical Trial
  • Status: Active, not recruiting
  • Phase: Phase 2
  • Intervention Type: Drug
  • Participants: 20
  • Start Date: April 4, 2018
A Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Administration of ALN-GO1 in Patients With Primary Hyperoxaluria Type 1
Clinical Trial
  • Status: Recruiting
  • Participants: 400
  • Start Date: May 2013
Rare Kidney Stone Consortium Biobank, Rare Diseases Clinical Research Network
Showing 1-7 of 7