A Phase 3, Open-label Study of Ifinatamab Deruxtecan Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (IDeate-Prostate01)
Status: Recruiting
Location: See all (274) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-2400) to treat mCRPC. The goal of this study is to learn if people who receive I-DXd live longer overall and live longer without the cancer growing or spreading than people who receive chemotherapy.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:
⁃ The main inclusion criteria include but are not limited to the following:
• Has histologically- or cytologically-confirmed adenocarcinoma of the prostate without small cell histology
• Has prostate cancer progression while on androgen deprivation therapy (ADT) (or post bilateral orchiectomy) within 6 months prior to Screening
• Has current evidence of distant metastatic disease (M1 disease) documented by either bone lesions on bone scan and/or soft tissue disease by computed tomography (CT)/magnetic resonance imaging (MRI)
• Has received prior treatment with 1 or 2 androgen receptor pathway inhibitors (ARPIs) and progressed during or after at least 8 weeks of treatment
• Has provided tumor tissue from a core or excisional biopsy from soft tissue not previously irradiated and obtained after disease progression on the most recent prior therapy
• Has recovered from adverse events (AEs) due to previous anticancer therapies
Locations
United States
Arizona
Mayo Clinic in Arizona - Phoenix ( Site 0044)
RECRUITING
Phoenix
California
City of Hope Comprehensive Cancer Center ( Site 0049)
RECRUITING
Duarte
City of Hope Lennar Foundation Cancer Center ( Site 0059)
RECRUITING
Irvine
Moores Cancer Center ( Site 0010)
RECRUITING
La Jolla
Cedars-Sinai Medical Center ( Site 0068)
RECRUITING
Los Angeles
UCLA Hematology/Oncology - Santa Monica ( Site 0002)
RECRUITING
Los Angeles
University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006)
RECRUITING
Orange
Stanford Cancer Center ( Site 0046)
RECRUITING
Palo Alto
Colorado
Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0053)
RECRUITING
Aurora
Connecticut
Yale-New Haven Hospital-Yale Cancer Center ( Site 0050)
RECRUITING
New Haven
Veterans Affairs Connecticut Healthcare System ( Site 0062)
RECRUITING
West Haven
Washington, D.c.
The GW Medical Faculty Associates ( Site 0057)
RECRUITING
Washington D.c.
Washington DC Veterans Affairs Medical Center ( Site 0056)
RECRUITING
Washington D.c.
Florida
Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077)
RECRUITING
Jacksonville
Georgia
Emory University School of Medicine- Grady Campus ( Site 0103)
RECRUITING
Atlanta
Winship Cancer Institute, Emory University ( Site 0003)
RECRUITING
Atlanta
Illinois
University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0063)
RECRUITING
Chicago
Kentucky
University of Kentucky Chandler Medical Center ( Site 0048)
RECRUITING
Lexington
Massachusetts
Beth Israel Deaconess Medical Center ( Site 0043)
RECRUITING
Boston
Dana Farber Cancer Institute ( Site 0012)
RECRUITING
Boston
Maryland
Greenebaum Comprehensive Cancer Center ( Site 0021)
RECRUITING
Baltimore
Michigan
University of Michigan ( Site 0005)
RECRUITING
Ann Arbor
Henry Ford Hospital ( Site 0035)
RECRUITING
Detroit
Cancer and Hematology Centers of Western Michigan ( Site 0015)
RECRUITING
Grand Rapids
Minnesota
Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078)
RECRUITING
Rochester
HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032)
RECRUITING
Saint Louis Park
HealthPartners Cancer Center at Regions Hospital ( Site 0052)
RECRUITING
Saint Paul
Montana
St. Vincent Frontier Cancer Center-Research ( Site 0037)
RECRUITING
Billings
Nebraska
Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island ( Site 0076)
RECRUITING
Grand Island
Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026)
RECRUITING
Omaha
New Jersey
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016)
RECRUITING
Hackensack
New Mexico
University of New Mexico Comprehensive Cancer Center ( Site 0022)
RECRUITING
Albuquerque
New York
Icahn School of Medicine at Mount Sinai ( Site 0009)
RECRUITING
New York
Great Lakes Cancer Care ( Site 0047)
RECRUITING
Williamsville
Ohio
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0061)
RECRUITING
Columbus
Oregon
VA Portland Health Care System ( Site 0038)
RECRUITING
Portland
Pennsylvania
Abramson Cancer Center - Penn Medicine ( Site 0079)
RECRUITING
Philadelphia
Perelman Center for Advanced Medicine ( Site 0067)
RECRUITING
Philadelphia
Tennessee
Memphis VA Medical Center ( Site 0072)
RECRUITING
Memphis
SCRI Oncology Partners ( Site 0074)
RECRUITING
Nashville
Texas
UT Southwestern Medical Center ( Site 0039)
RECRUITING
Dallas
University of Texas-MD Anderson Cancer Center ( Site 0055)
RECRUITING
Houston
Virginia
Blue Ridge Cancer Care ( Site 0024)
RECRUITING
Roanoke
Washington
Fred Hutchinson Cancer Center ( Site 0060)
RECRUITING
Seattle
VA Puget Sound Health Care System ( Site 0054)
RECRUITING
Seattle
Wisconsin
University Hospital and UW Health Clinics ( Site 0065)
RECRUITING
Madison
Medical College of Wisconsin ( Site 0008)
RECRUITING
Milwaukee
Other Locations
Argentina
Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 0136)
RECRUITING
Berazategui
Centro Medico Dra De Salvo ( Site 0132)
RECRUITING
Caba
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0131)
RECRUITING
La Rioja
Instituto Alexander Fleming ( Site 0125)
RECRUITING
Mar Del Plata
Instituto de Investigaciones Clinicas Mar del Plata ( Site 0129)
RECRUITING
Mar Del Plata
Centro Oncologico de Integracion Regional. COIR ( Site 0130)
RECRUITING
Mendoza
Sanatorio Parque ( Site 0126)
RECRUITING
Rosario
Centro de Diagnostico Investigación y Tratamiento Oncológico (CeDIT) ( Site 0135)
RECRUITING
Salta
Instituto San Marcos ( Site 0137)
RECRUITING
San Juan
Australia
Blacktown Hospital ( Site 0154)
RECRUITING
Blacktown
Gallipoli Medical Research Ltd ( Site 0153)
RECRUITING
Greenslopes
Macquarie University-MQ Health Clinical Trials Unit ( Site 0151)
RECRUITING
Macquarie University
Peter MacCallum Cancer Centre ( Site 0152)
RECRUITING
Melbourne
Fiona Stanley Hospital ( Site 0155)
RECRUITING
Murdock
Austria
Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0170)
RECRUITING
Linz
Uniklinikum Salzburg Universitaetsklinik für Innere Medizin III ( Site 0172)
RECRUITING
Salzburg
Klinikum Wels-Grieskirchen GmbH ( Site 0171)
RECRUITING
Wels
Brazil
Hospital Mario Penna ( Site 0179)
RECRUITING
Belo Horizonte
Hospital Universitário Evangélico Mackenzie ( Site 0181)
RECRUITING
Curitiba
Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0184)
RECRUITING
Porto Alegre
Hospital de Base de São José do Rio Preto ( Site 0176)
RECRUITING
São José Do Rio Preto
IBCC - Núcleo de Pesquisa e Ensino ( Site 0183)
RECRUITING
São Paulo
IPITEC ( Site 0189)
RECRUITING
São Paulo
Chile
Bradfordhill ( Site 0200)
RECRUITING
Santiago
FALP ( Site 0201)
RECRUITING
Santiago
China
Peking University First Hospital ( Site 1434)
RECRUITING
Beijing
Shanghai General Hospital ( Site 1449)
RECRUITING
Beijing
Jilin Province People's Hospital ( Site 1461)
RECRUITING
Changchun
Hunan Cancer Hospital ( Site 1411)
RECRUITING
Changsha
West China Hospital of Sichuan University ( Site 1451)
RECRUITING
Chengdu
West China Hospital, Sichuan University ( Site 1468)
RECRUITING
Chengdu
Chongqing University Three Gorges Hospital ( Site 1405)
RECRUITING
Chongqing
The First Affiliated Hospital of Chonqing Medical University ( Site 1406)
RECRUITING
Chongqing
The First Affiliated Hospital Of Fujian Medical University ( Site 1452)
RECRUITING
Fuzhou
Guangzhou First People's Hospital ( Site 1410)
RECRUITING
Guangzhou
Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1402)
RECRUITING
Guangzhou
Sun Yat-sen University Cancer Center ( Site 1409)
RECRUITING
Guangzhou
Sun Yat-Sen University Cancer Center ( Site 1467)
RECRUITING
Guangzhou
Zhejiang Cancer Hospital ( Site 1447)
RECRUITING
Hangzhou
The First Hospital of Jiaxing ( Site 1416)
RECRUITING
Jiaxing
Shandong Cancer Hospital ( Site 1421)
RECRUITING
Jinan
Jiangsu Province Hospital ( Site 1426)
RECRUITING
Nanjing
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 1425)
RECRUITING
Nanjing
Zhongda Hospital Southeast University ( Site 1427)
RECRUITING
Nanjing
Guangxi Medical University Cancer Hospital ( Site 1414)
RECRUITING
Nanning
The First Affiliated Hospital of Ningbo University ( Site 1419)
RECRUITING
Ningbo
Fudan University Shanghai Cancer Center ( Site 1400)
RECRUITING
Shanghai
Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1457)
RECRUITING
Shanghai
Shanghai Tenth People's Hospital ( Site 1441)
RECRUITING
Shanghai
Shanghai Tongji Hospital ( Site 1412)
RECRUITING
Shanghai
Zhongshan Hospital Fudan University ( Site 1430)
RECRUITING
Shanghai
First Affiliated Hospital Of Shanxi Medical University ( Site 1460)
RECRUITING
Taiyuan
The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 1469)
RECRUITING
Ürümqi
The First Affiliated Hospital of Wenzhou Medical University ( Site 1437)
RECRUITING
Wenzhou
Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1424)
RECRUITING
Wuhan
The first affiliated Hospital of Xi an Jiaotong University ( Site 1408)
RECRUITING
Xi'an
The Affiliated Hospital of Xuzhou Medical University ( Site 1438)
RECRUITING
Xuzhou
Henan Cancer Hospital ( Site 1472)
RECRUITING
Zhengzhou
The Fifth Affiliated Hospital of Sun Yat-Sen University ( Site 1459)
RECRUITING
Zhuhai
Colombia
Centro Cancerológico del Caribe (CECAC) ( Site 0227)
RECRUITING
Barranquilla
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0230)
RECRUITING
Bogota
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0229)
RECRUITING
Bogotá
Instituto Nacional De Cancerologia ( Site 0237)
RECRUITING
Bogotá
Instituto de Cancerología S.A.S ( Site 0234)
RECRUITING
Medellín
Oncologos Del Occidente ( Site 0231)
RECRUITING
Pereira
Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 0228)
RECRUITING
Valledupar
Denmark
Aalborg Universitetshospital, Syd ( Site 0293)
RECRUITING
Aalborg
Herlev and Gentofte Hospital ( Site 0290)
RECRUITING
Herlev
Odense Universitetshospital ( Site 0294)
RECRUITING
Odense
Vejle Sygehus ( Site 0291)
RECRUITING
Vejle
France
CHU Besançon ( Site 0305)
SUSPENDED
Besançon
Centre François Baclesse ( Site 0311)
RECRUITING
Caen
Clinique Francois Chenieux ( Site 0312)
RECRUITING
Limoges
Hôpital Privé Clairval ( Site 0303)
RECRUITING
Marseille
Centre Hospitalier Universitaire de Nîmes - Institut de Canc-Medical Oncology ( Site 0313)
RECRUITING
Nîmes
Hôpital Saint-Louis ( Site 0310)
RECRUITING
Paris
CHU de Rouen ( Site 0301)
RECRUITING
Rouen
Hôpital Foch ( Site 0309)
RECRUITING
Suresnes
Institut de Cancérologie de Lorraine Alexis Vautrin ( Site 0307)
RECRUITING
Vandœuvre-lès-nancy
Germany
Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0352)
RECRUITING
Berlin
Urologicum Duisburg ( Site 0361)
RECRUITING
Duisburg
Universitätsklinikum Frankfurt Goethe-Universität ( Site 0354)
RECRUITING
Frankfurt Am Main
Universitaetsklinik Hamburg-Eppendorf ( Site 0351)
RECRUITING
Hamburg
Universitaetsklinikum Schleswig Holstein ( Site 0360)
RECRUITING
Lübeck
klinikum rechts der isar der technischen universität münchen ( Site 0350)
RECRUITING
Munich
Klinikum Nuernberg Nord ( Site 0353)
RECRUITING
Nuremberg
Studienpraxis Urologie ( Site 0358)
RECRUITING
Nürtingen
Klinikum Stuttgart - Katharinenhospital ( Site 0355)
RECRUITING
Stuttgart
Greece
Henry Dunant Hospital ( Site 0385)
RECRUITING
Athens
Metropolitan General Hospital ( Site 0382)
RECRUITING
Athens
University General Hospital Attikon ( Site 0381)
RECRUITING
Chaidari Athens
General Oncology Hospital of Kifisia Agioi Anargyroi ( Site 0384)
RECRUITING
Kifissia
Athens Medical Center ( Site 0383)
RECRUITING
Marousi
Guatemala
Med Clinic ( Site 0403)
RECRUITING
Guatemala City
MEDI-K ( Site 0401)
RECRUITING
Guatemala City
Onco Go ( Site 0402)
RECRUITING
Guatemala City
Hong Kong Special Administrative Region
Queen Mary Hospital ( Site 0415)
RECRUITING
Hong Kong
Tuen Mun Hospital ( Site 0416)
RECRUITING
New Territories
Ireland
Cork University Hospital ( Site 0442)
RECRUITING
Cork
St Vincent's University Hospital ( Site 0441)
RECRUITING
Dublin
Tallaght University Hospital ( Site 0440)
RECRUITING
Dublin
Israel
Rambam Health Care Campus ( Site 0462)
RECRUITING
Haifa
Meir Medical Center ( Site 0464)
RECRUITING
Kfar Saba
Rabin Medical Center ( Site 0461)
RECRUITING
Petah Tikva
Sheba Medical Center ( Site 0460)
RECRUITING
Ramat Gan
Sourasky Medical Center ( Site 0463)
RECRUITING
Tel Aviv
Yitzhak Shamir Medical Center. ( Site 0466)
RECRUITING
Ẕerifin
Italy
Azienda USL 8 di Arezzo ( Site 0503)
RECRUITING
Arezzo
Humanitas Gavazzeni ( Site 0508)
RECRUITING
Bergamo
Azienda Ospedaliero Universitaria Policlinico Riuniti di Foggia ( Site 0510)
RECRUITING
Foggia
Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0500)
RECRUITING
Milan
Istituto Nazionale Tumori Regina Elena ( Site 0507)
RECRUITING
Rome
Istituto Clinico Humanitas ( Site 0504)
RECRUITING
Rozzano
Azienda Ospedaliero Universitaria Senese ( Site 0505)
RECRUITING
Siena
Azienda Ospedaliera Santa Maria Terni ( Site 0509)
RECRUITING
Terni
Centro Ricerche Cliniche di Verona ( Site 0506)
RECRUITING
Verona
Japan
University of Yamanashi Hospital ( Site 1506)
RECRUITING
Chūō
Harasanshin Hospital ( Site 1517)
RECRUITING
Fukuoka
Kyushu University Hospital ( Site 1515)
RECRUITING
Fukuoka
Gifu University Hospital ( Site 1527)
RECRUITING
Gifu
University of the Ryukyus Hospital ( Site 1519)
RECRUITING
Ginowan
Hamamatsu University Hospital ( Site 1520)
RECRUITING
Hamamatsu
Hiroshima University Hospital ( Site 1512)
RECRUITING
Hiroshima
Kagoshima City Hospital ( Site 1528)
RECRUITING
Kagoshima
Kagoshima University Hospital ( Site 1518)
RECRUITING
Kagoshima
Kanazawa Medical University Hospital ( Site 1507)
RECRUITING
Kahoku-gun
Shonan Kamakura General Hospital ( Site 1530)
RECRUITING
Kamakura
Hospital of the University of Occupational and Environmental Health, Japan ( Site 1510)
RECRUITING
Kitakyushu
Kobe University Hospital ( Site 1511)
RECRUITING
Kobe
Dokkyo Medical University Saitama Medical Center ( Site 1502)
RECRUITING
Koshigaya
National Hospital Organization Kumamoto Medical Center ( Site 1524)
RECRUITING
Kumamoto
Kurume University Hospital ( Site 1516)
RECRUITING
Kurume
University Hospital,Kyoto Prefectural University of Medicine ( Site 1525)
RECRUITING
Kyoto
The Jikei University Hospital ( Site 1504)
RECRUITING
Minato
Nagano Municipal Hospital ( Site 1526)
RECRUITING
Nagano
Nagasaki University Hospital ( Site 1523)
RECRUITING
Nagasaki
Nagoya University Hospital ( Site 1508)
RECRUITING
Nagoya
Niigata Cancer Center Hospital ( Site 1529)
RECRUITING
Niigata
Bell Land General Hospital ( Site 1509)
RECRUITING
Sakai
Toho University Sakura Medical Center ( Site 1503)
RECRUITING
Sakura
Hokkaido University Hospital ( Site 1500)
RECRUITING
Sapporo
Sapporo Medical University Hospital ( Site 1501)
RECRUITING
Sapporo
Tokyo Women's Medical University ( Site 1505)
ACTIVE_NOT_RECRUITING
Shinjuku
Tokushima University Hospital ( Site 1513)
RECRUITING
Tokushima
Ehime University Hospital ( Site 1514)
RECRUITING
Tōon
Yamaguchi University Hospital ( Site 1522)
RECRUITING
Ube
Oita University Hospital ( Site 1521)
RECRUITING
Yufu
Malaysia
Sarawak General Hospital ( Site 0526)
RECRUITING
Kuching
Sunway Medical Centre ( Site 0529)
RECRUITING
Petaling Jaya
Mexico
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0541)
RECRUITING
Guadalajara
Higiea Oncologia ( Site 0542)
RECRUITING
Mexico City
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran ( Site 0545)
RECRUITING
Mexico City
Hospital Universitario Dr. Jose Eleuterio Gonzalez ( Site 0540)
RECRUITING
Monterrey
Centro de Investigacion Clinica de Oaxaca ( Site 0543)
RECRUITING
Oaxaca City
Grupo Ollin Care ( Site 0544)
RECRUITING
Pachuca
Netherlands
Meander Medisch Centrum ( Site 0604)
RECRUITING
Amersfoort
Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 0602)
RECRUITING
Amsterdam
Martini Ziekenhuis ( Site 0621)
RECRUITING
Groningen
Ziekenhuisgroep Twente, locatie Almelo ( Site 0615)
RECRUITING
Hengelo
Tergooiziekenhuizen, locatie Hilversum ( Site 0619)
RECRUITING
Hilversum
Spaarne Gasthuis - Hoofddorp ( Site 0608)
RECRUITING
Hoofddorp
Maastricht UMC+ ( Site 0612)
RECRUITING
Maastricht
UMC St. Radboud ( Site 0601)
RECRUITING
Nijmegen
Erasmus Medisch Centrum ( Site 0611)
RECRUITING
Rotterdam
Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 0600)
RECRUITING
Schiedam
Haga Ziekenhuis locatie Leyweg ( Site 0607)
RECRUITING
The Hague
St. Antonius Ziekenhuis, locatie Utrecht ( Site 0620)
RECRUITING
Utrecht
VieCuri Medisch Centrum, locatie Venlo ( Site 0610)
RECRUITING
Venlo
Norway
Sykehuset Innlandet HF Gjøvik ( Site 0652)
RECRUITING
Gjøvik
Akershus Universitetssykehus-Onkologisk avdeling ( Site 0650)
RECRUITING
Lorenskog
Oslo universitetssykehus, Radiumhospitalet ( Site 0653)
RECRUITING
Oslo
St. Olavs Hospital-Kreftklinikken ( Site 0651)
RECRUITING
Trondheim
Peru
Unidad de Investigacion Oncologia Clínica Piura ( Site 0669)
RECRUITING
Castilla
Hospital Cayetano Heredia ( Site 0667)
RECRUITING
Lima
Instituto Nacional de Enfermedades Neoplásicas ( Site 0665)
RECRUITING
Lima
Instituto Neuro Cardiovascular de las Americas ( Site 0668)
RECRUITING
Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0666)
RECRUITING
Lima
Poland
Centrum Onkologii im prof Franciszka Lukaszczyka ( Site 0696)
RECRUITING
Bydgoszcz
Pratia Onkologia Katowice ( Site 0693)
RECRUITING
Katowice
Pratia MCM Krakow ( Site 0692)
RECRUITING
Krakow
Clinical Research Center Spółka z ograniczoną odpowiedzialnością MEDIC-R Sp.k ( Site 0688)
RECRUITING
Poznan
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 0686)
RECRUITING
Siedlce
Narodowy Instytut Onkologii im. Marii Skłodowskiej Curie ( Site 0685)
RECRUITING
Warsaw
Republic of Korea
Ulsan University Hospital ( Site 0793)
RECRUITING
Donggu
Chonnam National University Hwasun Hospital ( Site 0794)
RECRUITING
Hwasun Gun
The Catholic University of Korea St. Mary s Hospital ( Site 0795)
RECRUITING
Seocho-gu
Samsung Medical Center ( Site 0792)
RECRUITING
Seoul
Severance Hospital Yonsei University Health System ( Site 0790)
RECRUITING
Seoul
Asan Medical Center ( Site 0791)
RECRUITING
Songpagu
Singapore
National Cancer Centre Singapore ( Site 0760)
RECRUITING
Singapore
Tan Tock Seng Hospital ( Site 0761)
RECRUITING
Singapore
South Africa
Cancercare Rondebosch Oncology ( Site 0771)
RECRUITING
Cape Town
Wits Clinical Research ( Site 0776)
RECRUITING
Johannesburg
Curo Oncology Centre ( Site 0779)
RECRUITING
Pretoria
LIFE GROENKLOOF ( Site 0777)
RECRUITING
Pretoria
Wilgers Oncology Centre ( Site 0775)
RECRUITING
Pretoria
Spain
Hospital del Mar ( Site 0822)
RECRUITING
Barcelona
Hospital Vall D Hebron ( Site 0814)
RECRUITING
Barcelona
Hospital Universitario Reina Sofia ( Site 0816)
RECRUITING
Córdoba
Hospital Lucus Augusti ( Site 0813)
RECRUITING
Lugo
Hospital General Universitario Gregorio Marañón ( Site 0812)
RECRUITING
Madrid
Hospital Universitario Quiron Madrid ( Site 0823)
RECRUITING
Madrid
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA ( Site 0811)
RECRUITING
Majadahonda Madrid
Hospital Universitario Marqués de Valdecilla ( Site 0810)
RECRUITING
Santander
CHUS - Hospital Clinico Universitario ( Site 0815)
RECRUITING
Santiago De Compostela
Hospital Universitario Virgen de Valme ( Site 0819)
RECRUITING
Seville
Fundación Instituto Valenciano de Oncología ( Site 0821)
RECRUITING
Valencia
Sweden
Skånes Universitetssjukhus Malmö ( Site 0841)
RECRUITING
Malmo
Karolinska Universitetssjukhuset Solna ( Site 0843)
RECRUITING
Stockholm
Södersjukhuset ( Site 0844)
RECRUITING
Stockholm
Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 0840)
RECRUITING
Uppsala
Switzerland
Kantonspital Aarau ( Site 0857)
RECRUITING
Aarau
University Hospital Basel ( Site 0859)
RECRUITING
Basel
HFR Fribourg - Hôpital Cantonal ( Site 0858)
RECRUITING
Fribourg
Hopitaux Universitaires de Geneve HUG. ( Site 0856)
RECRUITING
Geneva
Stadtspital Triemli ( Site 0855)
RECRUITING
Zurich
Taiwan
Chang Gung Medical Foundation - Kaohsiung ( Site 0872)
RECRUITING
Kaohsiung City
Taichung Veterans General Hospital ( Site 0873)
RECRUITING
Taichung
Taipei Veterans General Hospital ( Site 0875)
RECRUITING
Taipei
National Taiwan University Hospital ( Site 0870)
RECRUITING
Taiwan
Thailand
Faculty of Medicine Siriraj Hospital ( Site 0885)
RECRUITING
Bangkoknoi
Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 0887)
RECRUITING
Dusit
Turkey
Adana Medical Park Seyhan Hastanesi ( Site 0906)
RECRUITING
Adana
Gazi University Health Research and Application Center Gazi Hospital ( Site 0903)
RECRUITING
Ankara
Hacettepe Universitesi Tip Fakultesi ( Site 0895)
RECRUITING
Ankara
Istanbul Universitesi Cerrahpasa ( Site 0896)
RECRUITING
Istanbul
Konya Necmettin Erbakan Universitesi ( Site 0905)
RECRUITING
Konya
Contact Information
Primary
Toll Free Number
Trialsites@msd.com
1-888-577-8839
Time Frame
Start Date: 2025-05-13
Estimated Completion Date: 2031-01-06
Participants
Target number of participants: 1440
Treatments
Experimental: I-DXd
Participants receive I-DXd 12mg/kg every 3 weeks (q3w)
Active_comparator: Docetaxel
Participants receive docetaxel 75 mg/m\^2 q3w and prednisone 10 mg/day or per approved product label
Related Therapeutic Areas
Sponsors
Collaborators: Daiichi Sankyo
Leads: Merck Sharp & Dohme LLC