Fecal Microbiota Transplantation in Refractory Clostridium Difficile Colitis

Who is this study for? Patients with Clostridium Difficile Infection
What treatments are being studied? Fecal Microbiota
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant stool from healthy donors to treat recurrent C. difficile colitis by incorporating the stool into capsules that are administered by the oral route.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:

• Study entry is open to adults (>18 years old) who have had three of more episodes of Clostridium difficile colitis within the previous 12 months.

Locations
United States
North Carolina
Duke University Medical Center
Recruiting
Durham
Contact Information
Primary
Gary M Cox, MD
gary.cox@duke.edu
919-668-3271
Time Frame
Start Date: April 2016
Estimated Completion Date: May 2023
Participants
Target number of participants: 10
Treatments
Experimental: fecal microbiota transplantation
fecal microbiota transplantation
Authors
Sponsors
Leads: Duke University

This content was sourced from clinicaltrials.gov

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