Application of Atomized Inhalation ICG in Thoracoscopic Surgery for Pulmonary Sequestration in Children: a Multicentre Prospective Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To investigate the safety and effectiveness of preoperative aerosol inhalation ICG solution for thoracoscopic accurate resection of congenital lung malformations in children.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 14
Healthy Volunteers: f
View:

• children with congenital lung malformations diagnosed by CT or MRI scan

Locations
Other Locations
China
Tongji Hospital
RECRUITING
Wuhan
Contact Information
Primary
Tianqi Zhu, MD
zhutianqi84@163.com
0086-13986295423
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2050-12-31
Participants
Target number of participants: 50
Treatments
Experimental: ICG for CLMs
Preoperative preparation ICG solution dissolved in 5ml of normal saline (dose 0.5mg/kg) was inhaled 30 minutes before surgery.~Operation method After entering the chest cavity, the fluorescence endoscope was switched to the fluorescence display mode, and the fluorescence-stained normal lung tissue and non-stained lesion tissue could be clearly displayed through the display screen, and the external boundary of the lesion was marked with an electric hook. The mediastinal pleura and pulmonary pleura were opened along the boundary of the lesion, and the lung tissue was split along the gap between the lesion and the lung tissue with an electric coagulation hook and an ultrasonic knife, and the lesion arteries and bronchi were freed. Smaller blood vessels could be cut by Ligasure or ultrasonic knife directly, and thicker blood vessels and bronchi should be cut by Hemolock until the lesion resection was completed.
Related Therapeutic Areas
Sponsors
Leads: Jiexiong Feng

This content was sourced from clinicaltrials.gov