Lhermitte-Duclos disease: A case report and literature review.

Journal: Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal Of Central South University. Medical Sciences
Treatment Used: Partial Resection
Number of Patients: 1
Published:
MediFind Summary

Summary: This case report describes a patient diagnosed with Lhermitte-Duclos disease (LDD), a rare brain tumor in the posterior fossa, treated with partial resection.

Conclusion: A patient with Lhermitte-Duclos disease (LDD), a rare brain tumor in the posterior fossa, treated with partial resection survived for 17 months.

Abstract

Lhermitte-Duclos disease (LDD) is a type of rare brain tumor located in posterior fossa. A patient with LDD located in the left cerebellum and vermis was admitted by the Department of Neurosurgery, Xiangya Hospital, Central South University. MRI scan showed slightly heterogeneous enhancement at the region close to vermis. The patient underwent partial resection on August 11, 2016 without postoperative chemoradiotherapy. The progress free survival was 11 months and the overall survival was 17 months. What the case reveals is that the partial resection is not beneficial to these patients with LDD as the residual lesion probably recurs in a short term after operation. The pathogenesis, diagnosis and treatment of LDD are explored and summarized in combination with relevant literature.

Authors
Zhiqiang Liu, Yanqing He, Jiaxin Fu, Jun Wu, Tao Song, Ying Wang, Tianxiang Huang

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