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Dr. Christopher L Bowlus

Regents Of The Univ Of Ca
Hepatology, Gastroenterology, Internal Medicine
Practicing approx. 31 years

Bio


Christopher Bowlus is an Internal Medicine specialist and a Hepatologist in Sacramento, California. Dr. Bowlus is a global expert in Sclerosing Cholangitis. He has been an author on 126 peer reviewed articles and participated in 1 clinical trial in the past 15 years. In particular, he has been an author on 44 peer reviewed articles regarding Sclerosing Cholangitis. Dr. Bowlus's top three areas of expertise are Cholangitis, Primary Biliary Cirrhosis, Sclerosing Cholangitis, and Cholestasis. He is licensed to treat patients in CA.

Contact

4860 Y St
Suite 2100
Sacramento, CA 95817, US

Latest Advances


  • Condition: Primary Sclerosing Cholangitis (PSC)
  • Journal: Journal of hepatology
  • Treatment Used: Obeticholic Acid (OCA)
  • Number of Patients: 76
  • Published —
This study investigated the safety and effectiveness of obeticholic acid (OCA) in the treatment of primary sclerosing cholangitis (liver disease; PSC).
  • Condition: Primary Sclerosing Cholangitis (PSC)
  • Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • Treatment Used: Tumor Necrosis Factor (TNF) Antagonists
  • Number of Patients: 141
  • Published —
This study evaluated the effects of tumor necrosis factor (TNF) antagonists (medicines that suppress the body's natural response to tumor necrosis factor, a protein produced by white blood cells that is involved in early inflammatory events) in patients with primary sclerosing cholangitis (chronic disease in which the bile ducts inside and outside the liver become inflamed and scarred, and eventually narrowed or blocked; PSC).
  • Condition: Primary Biliary Cholangitis (PBC)
  • Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • Treatment Used: Long-Term Obeticholic Acid (OCA)
  • Number of Patients: 17
  • Published —
This study determined the long-term effects of obeticholic acid (OCA) on liver damage and fibrosis in patients with primary biliary cholangitis (PBC), an autoimmune disease characterized by bile duct destruction that can progress to cirrhosis.
  • Condition: Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases
  • Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • Treatment Used: Vedolizumab
  • Number of Patients: 102
  • Published —
The study researched the outcomes of Vedolizumab in patients with primary sclerosing cholangitis and inflammatory bowel diseases.
  • Condition: Primary Biliary Cholangitis
  • Journal: Journal of autoimmunity
  • Treatment Used: Abatacept
  • Number of Patients: 16
  • Published —
This study tested the safety and efficacy of using biologics such as abatacept to treat patients with primary biliary cholangitis.

Clinical Trials


Clinical Trial
  • Status: Recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 75
  • Start Date: July 14, 2020
Long-term Safety and Tolerability Study of Linerixibat for the Treatment of Cholestatic Pruritus in Participants With Primary Biliary Cholangitis

All Publications
View All


  • Sponsor: American Association for the Study of Liver Diseases (AASLD)
  • Event Name: American Association for the Study of Liver Diseases: The Liver Meeting 2020
  • Published —
LONGITUDINAL CHANGES OF PRO‐C3 AND ELF ARE ASSOCIATED WITH HISTOLOGIC AND CLINICAL DISEASE PROGRESSION IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC)
  • Sponsor: American Association for the Study of Liver Diseases (AASLD)
  • Event Name: American Association for the Study of Liver Diseases: The Liver Meeting 2020
  • Published —
LONG‐TERM EFFICACY AND SAFETY OF OBETICHOLIC ACID IN PRIMARY BILIARY CHOLANGITIS: RESPONDER ANALYSIS OF OVER 5 YEARS OF TREATMENT IN THE POISE TRIAL

Contact

4860 Y St
Suite 2100
Sacramento, CA 95817, US

Affiliations

  • University Of California Davis Medical Center

Credentials

  • Graduate InstitutionSt. Louis College Of Physicians And Surgeons
    1990
  • Licenses
    Internal Medicine in CA
  • Board Certifications
    Gastroenterology
    Internal Medicine

Insurance

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