Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition

Status: Recruiting
Location: See location...
Intervention Type: Dietary Supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to determine whether advancing the timing of home parenteral nutrition from overnight to daytime regimens leads to improved glucose profiles and sleep quality, and other changes in plasma metabolic signatures.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 79
Healthy Volunteers: No
View:

• Adult male or non-pregnant female volunteers (age 18-79)

• Short bowel syndrome diagnosis

• Able and willing to give consent and comply with study procedures

• Currently on routine home parenteral nutrition (at least 6 months)

Locations
United States
Massachusetts
Massachusetts General Hospital
Recruiting
Boston
Contact Information
Primary
Hassan S Dashti, Ph.D., R.D.
hassan.dashti@mgh.harvard.edu
617-643-7167
Backup
Richa Saxena, Ph.D.
rsaxena@partners.org
Time Frame
Start Date: October 5, 2021
Estimated Completion Date: December 1, 2022
Participants
Target number of participants: 20
Treatments
Experimental: Nighttime cycled parenteral feeds followed by daytime cycled parenteral feeds
Patients will follow nighttime feeding regimen for one week, and then advance their feeds (approximately 12 hours earlier) to daytime feeding regimen for one week.
Authors
Hassan S Dashti
Related Therapeutic Areas
Sponsors
Collaborators: ASPEN Rhoads Research Foundation
Leads: Massachusetts General Hospital

This content was sourced from clinicaltrials.gov

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