HLA Antibodies in Systemic Lupus Erythematosus
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients Adults
• Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus
• Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants)
• With sera stored in the biobank
Locations
Other Locations
France
CHRU Amiens
RECRUITING
Amiens
Contact Information
Primary
Nicolas GUILLAUME, Pr
guillaume.nicolas@chu-amiens.fr
33+322087046
Time Frame
Start Date: 2025-02-10
Estimated Completion Date: 2027-05
Participants
Target number of participants: 30
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire, Amiens