What is the definition of Thrush?

Thrush is a yeast infection of the tongue and lining of the mouth.

What are the alternative names for Thrush?

Candidiasis - oral; Oral thrush; Fungal infection - mouth; Candida - oral

What are the causes for Thrush?

Certain germs normally live in our bodies. These include bacteria and fungi. While most germs are harmless, some can cause infection under certain conditions.

Thrush occurs in children and adults when conditions permit too much growth of a fungus called candida in your mouth. A small amount of this fungus normally lives in your mouth. It is most often kept in check by your immune system and other germs that also live in your mouth.

When your immune system is weak or when normal bacteria die, too much of the fungus can grow.

You are more likely to get thrush if you have one of the following:

  • You are in poor health.
  • You are very old. Young babies are also more likely to develop thrush.
  • You have HIV or AIDS.
  • You are receiving chemotherapy or drugs that weaken the immune system.
  • You are taking steroid medicine, including some inhalers for asthma and chronic obstructive pulmonary disease (COPD).
  • You have diabetes mellitus and your blood sugar is high. When your blood sugar is high, some of the extra sugar is found in your saliva and acts as food for candida.
  • You take antibiotics. Antibiotics kill some of the healthy bacteria that keep candida from growing too much.
  • Your dentures do not fit well.

Candida can also cause yeast infections in the vagina.

Thrush in newborns is somewhat common and easy to treat.

What are the symptoms for Thrush?

Symptoms of thrush include:

  • White, velvety sores in the mouth and on the tongue
  • Some bleeding when you brush your teeth or scrape the sores
  • Pain when swallowing

What are the current treatments for Thrush?

If you get mild thrush after taking antibiotics, eat yogurt or take over-the-counter acidophilus pills. This may help restore a healthy balance of germs in your mouth.

For a more severe case of thrush, your provider may prescribe:

  • Antifungal mouthwash (nystatin).
  • Lozenges (clotrimazole).
  • Antifungal medicines taken as a pill or syrup, these medicines include fluconazole (Diflucan) or itraconazole (Sporanox).

What is the outlook (prognosis) for Thrush?

Oral thrush can be cured. However, if your immune system is weak, thrush may come back or cause more serious problems.

What are the possible complications for Thrush?

If your immune system is weakened, candida can spread throughout your body, causing a serious infection.

This infection might affect your:

  • Brain (meningitis)
  • Esophagus (esophagitis)
  • Eyes (endophthalmitis)
  • Heart (endocarditis)
  • Joints (arthritis)

When should I contact a medical professional for Thrush?

Call your provider if:

  • You have thrush-like sores.
  • You have pain or difficulty swallowing.
  • You have symptoms of thrush and you are HIV positive, receiving chemotherapy, or you take medicines to suppress your immune system.

How do I prevent Thrush?

If you get thrush often, your provider may recommend taking antifungal medicine on a regular basis to keep thrush from coming back.

If you have diabetes mellitus, you can help prevent thrush by keeping good control of your blood sugar levels.

Candida - fluorescent stain
Mouth anatomy

REFERENCES

Daniels TE, Jordan RC. Diseases of the mouth and salivary glands. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 397.

Ericson J, Benjamin DK. Candida. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 261.

Lionakis MS, Edwards JE. Candida species. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 256.

  • Condition: Pseudomembranous Oral Candidiasis
  • Journal: European review for medical and pharmacological sciences
  • Treatment Used: 0.05% Chlorhexidine Plus 0.05% Cetylpyridinium Chloride Mouthwash
  • Number of Patients: 1
  • Published —
This case report describes a 50-year-old woman diagnosed with pseudomembranous oral candidiasis treated with a mouthwash containing 0.05% chlorhexidine plus 0.05% cetylpyridinium chloride.