What is the definition of Tieche-Jadassohn Nevus?

Tièche-Jadassohn nevus are rare blue moles that have several different types. Blue moles are more common in women and Asians, and mostly occur in late childhood or adolescence. Common blue moles are benign and do not change over the course of a lifetime. However, in rare instances, cellular blue moles can become a form of malignant melanoma. Blue moles are caused by incomplete migration of melanocytes, while the blue color is caused by the Tyndall effect, where shorter wavelengths of incident light are scattered by melanocytes (melanin-forming cells). Blue moles are usually blue because their melanocytes are deeper than those of brown moles.

What are the symptoms for Tieche-Jadassohn Nevus?

Symptoms of the common blue mole are the appearance of a single blue or bluish, smooth surfaced, round or oval macule, papule, or plaque, usually found on hands or feet, buttocks, scalp, face, or below the nail. Rarely, blue moles can appear in the vagina, cervix, spermatic cord, lymph nodes, prostate, and mouth. Common blue moles are usually 0.5-to-1 cm in diameter. Cellular blue moles are at least 1 cm and more nodular. While usually blue, these moles can also be grey, brown, or yellow.

What are the current treatments for Tieche-Jadassohn Nevus?

Blue moles usually require no treatment; however, those on the scalp can be surgically removed as a preventative measure. Blue moles larger than 1 cm that change appearance or suddenly appear in older adults should be examined to rule out melanoma. Blue moles are also removed for cosmetic reasons.
  • Condition: Cutaneous Melanoma Metastases and Rare Non-Melanoma Skin Cancer
  • Journal: Anticancer research
  • Treatment Used: Electrochemotherapy
  • Number of Patients: 68
  • Published —
This study tested the safety and efficacy of using electrochemotherapy to treat patients with cutaneous melanoma metastases and rare non-melanoma skin cancer.
  • Condition: Children with Blue Rubber Bleb Nevus Syndrome
  • Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
  • Treatment Used: Sirolimus
  • Number of Patients: 26
  • Published —
The study researched the use of Sirolimus in children with blue rubber bleb nevus syndrome.