Tracheoesophageal Fistula

Condition 101

What is the definition of Tracheoesophageal Fistula?

Tracheoesophageal fistula (TEF) is a life-threatening condition in which there is an abnormal connection between the esophagus and trachea (windpipe). The esophagus and trachea run next to each other through the chest cavity. The esophagus carries food and saliva to the stomach, while the trachea ca ...

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What are the alternative names for Tracheoesophageal Fistula?

  • Tracheoesophageal fistula with or without esophageal atresia
  • TE fistula
  • TEF

Is Tracheoesophageal Fistula an inherited disorder?

In most cases, tracheoesophageal fistula (TEF) is not inherited and there is only one affected person in a family. When TEF is isolated (i.e. does not occur with any other abnormalities), it is considered a multifactorial condition (caused by a combination of various genetic and environmental factors). However, in most isolated cases, no specific genetic changes or environmental factors have been proven to cause the condition. When TEF occurs as a feature of a genetic syndrome or chromosome abnormality, it may follow the inheritance pattern and recurrence risk for the underlying condition. In these cases, it may be caused by changes in single genes or chromosomes, or it may be multifactorial.

Data Source : GARD